Chiral synthesis and pharmacological evaluation of NPS 1407: A potent, stereoselective NMDA receptor antagonist

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 21, 2000, Pages 2411-2415

  Moe, Scott T ^a   Smith, Daryl L ^a   DelMar, Eric G ^a   Shimizu, Scot M ^a   Van Wagenen, Bradford C ^a   Balandrin, Manuel F ^a   Chien, Yongwei ^a   Raszkiewicz, Joanna L ^a   Artman, Linda D ^a   White, H Steve ^b   Mueller, Alan L ^a  

^a NPS Pharmaceutical Inc   (United States)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 1,1 BIS(3 FLUOROPHENYL)BUTANE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CHIRALITY; DRUG POTENCY; DRUG SYNTHESIS; MOUSE; NEUROPROTECTION; NONHUMAN; RACEMIC MIXTURE; STEREOCHEMISTRY;

ANIMALIA;

EID: 0034613595     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00470-4     Document Type: Article

References (27)