Tamoxifen up-regulates catalase production, inhibits vessel wall neutrophil infiltration, and attenuates development of experimental abdominal aortic aneurysms

Journal of Vascular Surgery

Volumn 41, Issue 1, 2005, Pages 108-114

  Grigoryants, Vladimir ^a   Hannawa, Kevin K ^a   Pearce, Charles G ^a   Sinha, Indranil ^a   Roelofs, Karen J ^a   Ailawadi, Gorav ^a   Deatrick, Kristopher B ^a   Woodrum, Derek T ^a   Cho, Brenda S ^a   Henke, Peter K ^a   Stanley, James C ^a   Eagleton, Matthew J ^a   Upchurch Jr , Gilbert R ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMITROLE; CATALASE; ENZYME INHIBITOR; GELATINASE B; PANCREATIC ELASTASE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; SODIUM CHLORIDE; TAMOXIFEN;

ABDOMINAL AORTA; ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DIAMETER; ARTICLE; BLOOD VESSEL WALL; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SYNTHESIS; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PERFUSION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; UPREGULATION; WESTERN BLOTTING; ZYMOGRAPHY;

AMITROLE; ANIMALS; AORTIC ANEURYSM, ABDOMINAL; CATALASE; IMMUNOHISTOCHEMISTRY; MALE; MATRIX METALLOPROTEINASE 9; NEUTROPHIL INFILTRATION; PANCREATIC ELASTASE; RATS; RATS, SPRAGUE-DAWLEY; SELECTIVE ESTROGEN RECEPTOR MODULATORS; TAMOXIFEN; UP-REGULATION;

EID: 19944430654     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jvs.2004.09.033     Document Type: Article

References (27)

1. Ailawadi G, Eliason JL, Roelofs KJ, Sinha I, Hannawa KK, Kaldjian EP, et al. Gender differences in experimental aortic aneurysm formation. Arterioscler Thromb Vasc Biol 2004;24:2116-22.
2. H.G. Alcorn, S.K. Wolfson, K. Suttin-Tyrrell, L.H. Kuller, D. O'Leary Risk factors for abdominal aortic aneurysms in older adults enrolled in the Cardiovascular Health Study Arterioscler Thromb Vasc Biol 16 1996 963 970
3. B. Martin-McNulty, D.M. Tham, V.D. Cunha, J.J., W. Ho 17 β-estradiol attenuates development of angiotensin II-induced aortic abdominal aneurysm in apolipoprotein E-deficient mice Arterioscler Thromb Vasc Biol 23 2003 1627 1632
4. B.L. Riggs, L.C. Hartmann Selective estrogen-receptor modulators: mechanism of action and application to clinical practice N Engl J Med 348 2003 618 629
5. G.A. Figtree, Y. Lu, C.M. Webb, P. Collins Raloxifen acutely relaxes rabbit coronary arteries in vitro by an estrogen receptor-dependent and nitric oxide-dependent mechanism Circulation 100 1999 1095 1101
6. R.K. Dubey, Y.Y. Tyurina, TyurinVA, D.G. Gillespie, R.A. Branch, E.K. Jackson Estrogen and tamoxifen metabolites protect smooth muscle cell membrane phospholipids against peroxidation and inhibit cell growth Circ Res 84 1999 229 239
7. E.R. Kisanga, J. Gjerde, J. Schjott, G. Mellgren, E.A. Lien Tamoxifen administration and metabolism in nude mice and rats J Steroid Biochem 34 2003 361 367
8. S. Anidjar, J.L. Salzmann, D. Gentric, P. Lagneau, J.P. Camilleri, J.B. Michel Elastase-induced experimental aneurysms in rats Circulation 82 1990 973 981
9. A.E. Dikalova, M.B. Kadiiska, R.P. Mason An in vivo ESR spin-trapping study: free radical generation in rats from formate intoxication--role of the Fenton reaction Proc Natl Acad Sci 98 2001 13549 13553
10. G.R. Upchurch Jr, J.W. Ford, S.J. Weiss, B.S. Knipp, D.A. Peterson, R.W. Thompson Nitric oxide inhibition increases matrix metalloproteinase-9 expression by rat aortic smooth muscle cells in vitro J Vasc Surg 34 2001 76 83
11. S. Kobayashi, N. Inoue, H. Azumi, T. Seno, K. Hirata, S. Kawashima Expressional changes of the vascular antioxidant system in the atherosclerotic coronary arteries J Atheroscler Thromb 9 2002 184 190
12. D.G. Harrison Endothelial function and oxidant stress Clin Cardiol 20 Suppl II 1997 II-11 II-17
13. H. Cai, D.G. Harrison Endothelial dysfunction in cardiovascular disease: the role of oxidant stress Circ Res 87 2000 840 844
14. T.J. Guzik, N.J. West, E. Black, D. McDonald, C. Ratnatunga, R. Pillai Vascular superoxide production by NADPH oxidase: association with endothelial dysfunction and clinical risk factors Circ Res 86 2000 e85 e90
15. K.K. Griendling, FitzGerald Oxidative stress and cardiovascular injury Part I: Basic mechanisms and in vivo monitoring of ROS Circulation 108 2003 1912 1916
16. S. Ulker, D. McMaster, P.P. McKeown, U. Bayraktutan Impaired activity of antioxidant enzymes elicit endothelial dysfunction in spontaneous hypertensive rats despite enhanced vascular nitric oxide generation Cardiovasc Res 59 2003 488 500
17. S. Rajagopalan, X. Meng, S. Ramasamy, D.G. Harrison, Z.S. Galis Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro J Clin Invest 98 1996 2572 2579
18. G.M. Longo, W. Xiong, T.C. Greiner, Y. Zhao, N. Fiotti, B.T. Baxter Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms J Clin Invest 110 2002 625 632
19. F.J. Miller, W.J. Sharp, X. Fang, L.W. Oberley, T.D. Oberley, N.L. Weintraub Oxidative stress in human aortic aneurysms: a potential mediator of aneurysmal remodeling Arterioscler Thromb Vasc Biol 22 2002 560 565
20. S. Wassmann, U. Laufs, D. Stamenkovic, W. Linz, J.P. Stasch, K. Ahlbory Raloxifen improves endothelial dysfunction in hypertension by reduced oxidative stress and enhanced nitric oxide production Circulation 105 2002 2083 2087
21. S.H. Mehta, K.M. Dhandapani, L.M. De Sevilla, R.C. Webb, V.B. Mahesh, D.W. Brann Tamoxifen, a selective estrogen receptor modulator, reduces ischemic damage caused by middle cerebral artery occlusion in the ovariectomized female rat Neuroendocrinology 77 2003 44 50
22. W.M. Wu, B.F. Lin, Y.C. Su, J.L. Suen, B.L. Chiang Tamoxifen decreases renal inflammation and alleviates disease severity in autoimmune NZB/WF1 mice Scan J Immunol 52 2000 393 400
23. H.S. Rosario, S.W. Waldo, S.A. Becker, G.W. Schmid-Schonbein Pancreatic trypsin increases matrix metalloproteinase-9 accumulation and activation during acute intestinal ischemia-reperfusion in the rat Am J Pathol 164 2004 1707 1716
24. X.L. Ma, F. Gao, J. Chen, T.A. Christopher, B.L. Lopez, E.H. Ohlstein Endothelial protective and antishock effects of a selective estrogen receptor modulator in rats Am J Physiol Heart Circ Physiol 280 2001 H876 84
25. H. Yang, M. Shi, A. Richardson, J. Vijg, Z. Guo Attenuation of leukocyte-endothelium interaction by antioxidant enzymes Free Radic Biol Med 35 2003 266 276
26. D. Zanger, B. Yang, J. Ardans, M.A. Waclawiw, G. Csako, L.M. Wahl Divergent effects of hormone therapy on serum markers of inflammation in postmenopausal women with coronary artery disease on appropriate medical management J Am Col Cardiol 36 2000 1797 1802
27. Eliason JL, Ailawadi GA, Sinha I, Ford JW, Deogracias M, Roelofs KJ, et al. Neutrophil depletion inhibits experimental aortic aneurysm formation unrelated to MMP-2 and MMP-9. American Association of Vascular Surgery Annual Meeting, Chicago, Ill, June, 2003; Abstract LL1:44.