Polymorphism of the human immunodeficiency virus type 2 (HIV-2) protease gene and selection of drug resistance mutations in HIV-2-infected patients treated with protease inhibitors

Journal of Clinical Microbiology

Volumn 43, Issue 1, 2005, Pages 484-487

  Damond, F ^a,b   Brun Vezinet, F ^a,b   Matheron, S ^a   Peytavin, G ^a   Campa, P ^a   Pueyo, S ^b   Mammano, F ^b   Lastere, S ^a,b   Farfara, I ^a   Simon, F ^c   Chene, G ^b   Descamps, D ^a,b  

^a BICHAT HOSPITAL   (France)

^b INSERM   (France)

^c INSTITUT PASTEUR DE DAKAR   (Senegal)

Author keywords

[No Author keywords available]

Indexed keywords

INDINAVIR; NELFINAVIR; PROTEINASE; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR;

ADULT; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; FOLLOW UP; GENE MUTATION; GENOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LONGITUDINAL STUDY; MALE; PRIORITY JOURNAL;

ADULT; DRUG RESISTANCE, VIRAL; FEMALE; HIV INFECTIONS; HIV PROTEASE; HIV PROTEASE INHIBITORS; HIV-2; HUMANS; MALE; MUTATION; POLYMORPHISM, GENETIC;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2;

EID: 19944429697     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.43.1.484-487.2005     Document Type: Article

References (22)

1. Bock, P. J., and D. M. Markovitz. 2001. Infection with HIV-2. AIDS 15:S35-S45.
2. Bossi, P., M. Mouroux, A. Yvin, F. Bricaire, H. Agut, J.-M. Huraux, C. Katlama, and V. Calvez. 1999. Polymorphism of the human immunodeficiency virus type 1 (HIV-1) protease gene and response of HIV-1-infected patients to a protease inhibitor. J. Clin. Microbiol. 37:2910-2912.
3. Cane, P. A., A. de Ruiter, P. Rice, M. Wiselka, R. Fox, and D. Pillay. 2001. Resistance associated mutations in subtype C HIV-1 protease inhibitor treated and untreated patients, Antivir. Ther. 6(Supp. 1):114.
4. Colson, P., M. Henry, C. Tourres, D. Lozachmeur, H. Gallais, J. A. Gastaut, J. Moreau, and C. Tamalet. 2004. Polymorphism and drug-selected mutations in the protease gene of human immunodeficiency virus type 2 from patients living in southern France. J. Clin. Microbiol. 42:570-577.
5. Condra, J. H., W. A. Schleif, O. M. Blahy, L. J. Gabryelski, D. J. Graham, J. C. Quintero, A. Rhodes, H. L. Robbins, E. Roth, M. Shivaprakash, et al. 1995. In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors. Nature 374:569-571.
6. Damond, F., M. Gueudin, S. Pueyo, I. Farfara, D. L. Robertson, D. Descamps, G. Chène, S. Matheron, P. Campa, F. Brun-Vézinet, and F. Simon. 2002. Plasma RNA viral load in human immunodeficiency virus type 2 subtype A and subtype B infections. J. Clin. Microbiol. 40:3654-3659.
7. Damond, F., M. Worobey, P. Campa, I. Farfara, G. Collin, S. Matheron, F. Brun-Vezinet, D. L. Robertson, and F. Simon. 2004. The identification of a highly divergent HIV-2 in France and a proposai for a new HIV-2 classification. AIDS Res. Hum. Retrovir. 20:666-672.
8. D'Aquila, R. T., J. M. Schapiro, F. Brun-Vézinet, B. Clotet, B. Conway, L. M. Demeter, C. Loveday, R. M. Grant, V. A. Johnson, D. R. Kuritzkes, R. W. Shafer, and D. D. Richman. 2002. Drug resistance mutations in HIV-1. Top. HIV Med. 10:21-25.
9. Kanki, P. J., and K. M. De Cock. 1994. Epidemiology and natural history of HIV-2. AIDS 8:S85-S93.
10. Kimura, M. 1980. A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. J. Mol. Evol. 16:111-120.
11. Kozal, M. J., N. Shah, N. Shen, R. Yang, R. Fucini, T. C. Merigan, D. D. Richman, D. Morris, E. Hubbell, M. Chee, and T. R. Gingeras. 1996. Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays. Nat. Med. 2:753-759.
12. Masquelier, B., G. Peytavin, C. Leport, C. Droz, S. Duran, R. Verdon, J. M. Besnier, G. Chene, F. Raffi, and F. Brun-Vezinet. 2002. Mechanisms of early virologic failure in antiretroviral-naive patients starting protease inhibitor-containing regimens: the APROVIR Study. J. Infect. Dis. 186:1503-1507.
13. Matheron, S., G. Mendoza-Sassi, F. Simon, R. Olivares, J. P. Coulaud, and F. Brun-Vezinet. 1997. HIV-1 and HIV-2 AIDS in African patients living in Paris. AIDS 11:934-936.
14. Matheron, S., S. Pueyo, F. Damond, F. Simon, A. Lepretre, P. Campa, R. Salamon, G. Chene, and F. Brun-Vezinet. 2003. Factors associated with clinical progression in HIV-2 infected-patients: the French ANRS cohort. AIDS 17:2593-2601.
15. Myers, G., B. Foley, J. W. Mellors, B. T. Korber, K. T. Jeang, and S. Wain-Hobson. 1996. Human retroviruses and AIDS 1996: a compilation and analysis of nucleic acid and amino acid sequences. Theoretical Biology and Biophysic Group, Los Alamos National Laboratory, Los Alamos, N.M.
16. Palmer, S., R. W. Shafer, and T. C. Merigan. 1999. Highly drug-resistant HIV-1 clinical isolates are cross-resistant to many antiretroviral compounds in current clinical development. AIDS 13:661-667.
17. Patick, A. K., M. Duran, Y. Cao, et al. 1996. Personal communication.
18. Pieniazek, D., D. Ellenberger, L. M. Janini, A. C. Ramos, J. Nkengasong, M. Sassan-Morokro, D. J. Hu, I. M. Coulibally, E. Ekpini, C. Bandea, A. Tanuri, A. E. Greenberg, S. Z. Wiktor, and M. A. Rajfield. 1999. Predominance of human immunodeficiency virus type 2 subtype B in Abidjan, Ivory Coast. AIDS Res. Hum. Retrovir. 15:603-608.
19. Pieniazek, D., M. Rayfield, D. Hu, J. Nkengasong, V. Soriano, W. Heneine, C. Zeh, S. Agwale, C. Wambebe, L. Odama, S. Wiktor, and M. Kalish. 2004. HIV-2 protease sequences of subtypes A and B harbor multiple mutations associated with protease inhibitor resistance in HIV-1. AIDS 18:495-502.
20. Rodés, B., A. Holguín, V. Soriano, M. Dourana, K. Mansinho, F. Antunes, and J. González-Lahoz. 2000. Emergence of drug resistance mutations in human immunodeficiency virus type 2-infected subjects undergoing antiretroviral therapy. J. Clin. Microbiol. 38:1370-1374.
21. Soriano, V., P. Gomes, W. Heneine, A. Holguin, M. Doruana, R. Antunes, K. Mansinho, W. M. Switzer, C. Araujo, V. Shanmugam, H. Lourenco, J. Gonzalez-Lahoz, and F. Antunes. 2000. Human immunodeficiency virus type 2 (HIV-2) in Portugal: clinical spectrum, circulating subtypes, virus isolation, and plasma viral load. J. Med. Virol. 61:111-116.
22. van der Ende, M. E., C. Guillon, P. H. Boers, T. D. Ly, R. A. Gruters, A. D. Osterhaus, and M. Schutten. 2000. Antiviral resistance of biologic HIV-2 clones obtained from individuals on nucleoside reverse transcriptase inhibitor therapy. J. Acquir. Immune Defic. Syndr. 25:11-18.