Evaluation of [ 123I]IBZM pinhole SPECT for the detection of striatal dopamine D 2 receptor availability in rats

NeuroImage

Volumn 24, Issue 3, 2005, Pages 822-831

  Scherfler, Christoph ^a   Scholz, Sonja W ^a   Donnemiller, Eveline ^a   Decristoforo, Clemens ^a   Oberladstätter, Michael ^a   Stefanova, Nadia ^a   Diederen, Eric ^a   Virgolini, Irene ^a   Poewe, Werner ^a   Wenning, Gregor K ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

123I IBZM; Dopamine D 2 and D 3 receptor system; Huntington's disease; MRI coregistration; Pinhole SPECT; Quinolinic acid animal model; Single photon emission computed tomography; Small animal imaging

Indexed keywords

AMPHETAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; IODINE 123; N [(1 ETHYL 2 PYRROLIDINYL)METHYL] 3 IODO 6 METHOXYSALICYLAMIDE; PHOSPHOPROTEIN DARPP 32; QUINOLINIC ACID; RADIOLIGAND; 3 IODO 2 HYDROXY 6 METHOXY N ((1 ETHYL 2 PYRROLIDINYL)METHYL)BENZAMIDE; 3-IODO-2-HYDROXY-6-METHOXY-N-((1-ETHYL-2-PYRROLIDINYL)METHYL)BENZAMIDE; BENZAMIDE DERIVATIVE; DIAGNOSTIC AGENT; DOPAMINE RECEPTOR BLOCKING AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NERVE PROTEIN; PHOSPHOPROTEIN; PYRROLIDINE DERIVATIVE; RADIOPHARMACEUTICAL AGENT;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; BRAIN REGION; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION ANALYSIS; COST EFFECTIVENESS ANALYSIS; DOSE RESPONSE; HUNTINGTON CHOREA; IMAGING; IMMUNOHISTOCHEMISTRY; LOCOMOTION; MALE; MEASUREMENT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTICAL DENSITY; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR OCCUPANCY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TIME; ANIMAL; BRAIN LEVEL; CHEMICALLY INDUCED DISORDER; COMPUTER ASSISTED DIAGNOSIS; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; METHODOLOGY; MOTOR ACTIVITY; NEOSTRIATUM; NERVE CELL; PATHOLOGY; PHYSIOLOGY; SCINTILLATION CAMERA; SCINTISCANNING; STATISTICAL MODEL; TISSUE DISTRIBUTION; WISTAR RAT;

ANIMALS; BENZAMIDES; BRAIN CHEMISTRY; DOPAMINE AND CAMP-REGULATED PHOSPHOPROTEIN 32; DOPAMINE ANTAGONISTS; GAMMA CAMERAS; HUNTINGTON DISEASE; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; LINEAR MODELS; MALE; MOTOR ACTIVITY; NEOSTRIATUM; NERVE TISSUE PROTEINS; NEURONS; PHOSPHOPROTEINS; PYRROLIDINES; QUINOLINIC ACID; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D2; RECEPTORS, N-METHYL-D-ASPARTATE; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 19944429544     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2004.10.005     Document Type: Article

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