Lack of association between occult hepatitis B virus DNA viral load and aminotransferase levels in patients with hepatitis C virus-related chronic liver disease

Journal of Gastroenterology and Hepatology (Australia)

Volumn 19, Issue 12, 2004, Pages 1343-1347

  Fujiwara, Kei ^a   Tanaka, Yasuhito ^a   Orito, Etsuro ^a   Ohno, Tomoyoshi ^a   Kato, Takanobu ^a   Sugauchi, Fuminaka ^a   Suzuki, Seiji ^a   Hattori, Yuko ^a   Sakurai, Mayumi ^a   Hasegawa, Izumi ^a   Ozasa, Takashi ^a   Kanie, Futoshi ^b   Kano, Hideyuki ^b   Ueda, Ryuzo ^a   Mizokami, Masashi ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b Nagoya Life Insurance Medical Clinic   (Japan)

Author keywords

Aminotransferase; Hepatitis C virus; Occult hepatitis B virus infection; Real time detection polymerase chain reaction

Indexed keywords

AMINOTRANSFERASE; HEPATITIS B CORE ANTIGEN; VIRUS DNA;

ADULT; ANTIGEN DETECTION; ARTICLE; BLOOD SAMPLING; CHRONIC LIVER DISEASE; CLINICAL ARTICLE; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HEPATITIS B VIRUS; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; MALE; OUTPATIENT; PREVALENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; VIRUS DETECTION; VIRUS LOAD;

EID: 19944428114     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2004.03439.x     Document Type: Article

References (25)

1. Brechot C, Degos F, Lugassy C et al. Hepatitis B virus DNA in patients with chronic liver disease and negative tests for hepatitis B surface antigen. N. Engl. J. Med. 1985; 312: 270-6.
2. Yotsuyanagi H, Yasuda K, Iino S et al. Persistent viremia after recovery from self-limited acute hepatitis B. Hepatology 1998; 27: 1377-82.
3. Mason AL, Xu L, Guo L, Kuhns M, Perrillo RP. Molecular basis for persistent hepatitis B virus infection in the liver after clearance of serum hepatitis B surface antigen. Hepatology 1998; 27: 1736-42.
4. Cacciola I, Pollicino T, Squadrito G, Cerenzia G, Orlando ME, Raimondo G. Occult hepatitis B virus infection in patients with chronic hepatitis C liver disease. N. Engl. J. Med. 1999; 341: 22-6.
5. De Maria N, Colantoni A, Friedlander L et al. The impact of previous HBV infection on the course of chronic hepatitis C. Am. J. Gastroenterol. 2000; 95: 3529-36.
6. Kazemi-Shirazi L, Petermann D, Muller C. Hepatitis B virus DNA in sera and liver tissue of HBsAg negative patients with chronic hepatitis C. J. Hepatol. 2000; 33: 785-90.
7. Wang JT, Wang TH, Sheu JC, Shih LN, Lin JT, Chen DS. Detection of hepatitis B virus DNA by polymerase chain reaction in plasma of volunteer blood donors negative for hepatitis B surface antigen. J. Infect. Dis. 1991; 163: 397-9.
8. Marusawa H, Uemoto S, Hijikata M et al. Latent hepatitis B virus infection in healthy individuals with antibodies to hepatitis B core antigen. Hepatology 2000; 31: 488-95.
9. Uchida T, Kaneita Y, Gotoh K et al. Hepatitis C virus is frequently coinfected with serum marker-negative hepatitis B virus: probable replication promotion of the former by the latter as demonstrated by in vitro cotransfection. J. Med. Virol 1997; 52: 399-405.
10. Koike K, Kobayashi M, Gondo M, Hayashi I, Osuga T, Takada S. Hepatitis B virus DNA is frequently found in liver biopsy samples from hepatitis C virus-infected chronic hepatitis patients. J. Med. Virol. 1998; 54: 249-55.
11. Sagnelli E, Coppola N, Scolastico C et al. Isolated anti-HBc in chronic hepatitis C predicts a poor response to interferon treatment. J. Med. Virol. 2001; 65: 681-7.
12. Brechot C, Thiers V, Kremsdorf D, Nalpas B, Pol S, Paterlini-Brechot P. Persistent hepatitis B virus infection in subjects without hepatitis B surface antigen: clinically significant or purely 'occult'? Hepatology 2001; 34: 194-203.
13. Chazouilleres O, Mamish D, Kim M et al. 'Occult' hepatitis B virus as source of infection in liver transplant recipients. Lancet 1994; 343: 142-6.
14. Uemoto S, Sugiyama K, Marusawa H et al. Transmission of hepatitis B virus from hepatitis B core antibody-positive donors in living related liver transplants. Transplantation 1998; 65: 494-9.
15. Sakamaki H, Sato Y, Mori SI et al. Hepatitis B virus reactivation in a patient with chronic GVHD after allogeneic peripheral blood stem cell transplantation. Int. J. Hematol. 2001; 74: 342-6.
16. Lau JY, Mizokami M, Ohno T, Diamond DA, Kniffen J, Davis GL. Discrepancy between biochemical and virological responses to interferon-alpha in chronic hepatitis C. Lancet 1993; 342: 1208-9.
17. Ohno T, Mizokami M, Wu RR et al. New hepatitis C virus (HCV) genotyping system that allows for identification of HCV genotypes 1a, 1b, 2a, 2b, 3a, 3b, 4, 5a, and 6a. J. Clin. Microbiol. 1997; 35: 201-7.
18. Abe A, Inoue K, Tanaka T et al. Quantitation of hepatitis B virus genomic DNA by real-time detection PCR. J. Clin. Microbiol. 1999; 37: 2899-903.
19. Fukuda R, Ishimura N, Niigaki M et al. Serologically silent hepatitis B virus coinfection in patients with hepatitis C virus-associated chronic liver disease: clinical and virological significance. J. Med. Virol. 1999; 58: 201-7.
20. Kobyashi M, Chayama K, Arase Y et al. Progressive and sufficient decrease of hepatitis B core antibody can predict the disappearance of hepatitis B virus DNA in Japanese patients with hepatitis B surface antigen clearance. J. Gastroenterol. 2000; 35: 753-7.
21. Yotsuyanagi H, Yasuda K, Moriya K et al. Frequent presence of HBV in the sera of HBsAg-negative, anti-HBc-positive blood donors. Transfusion 2001; 41: 1093-9.
22. Zervou EK, Dalekos GN, Boumba DS, Tsianos EV. Value of anti-HBc screening of blood donors for prevention of HBV infection: results of a 3-year prospective study in Northwestern Greece. Transfusion 2001; 41: 652-8.
23. Komori M, Yuki N, Nagaoka T et al. Long-term clinical impact of occult hepatitis B virus infection in chronic hepatitis B patients. J. Hepatol. 2001; 35: 798-804.
24. Shin CM, Lo SJ, Miyamura T, Chen SY, Lee YH. Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein in HuH-7 cells. J. Virol. 1993; 67: 5823-32.
25. Schuttler CG, Fiedler N, Schmidt K, Repp R, Gerlich WH, Schaefer S. Suppression of hepatitis B virus enhancer 1 and 2 by hepatitis C virus core protein. J. Hepatol. 2002; 37: 855-62.