Relationship of number of medications to functional status, health, and quality of life for the frail home-based older adult

OTJR Occupation, Participation and Health

Volumn 24, Issue 4, 2004, Pages 151-160

  Classen, Sherrilene ^a   Mann, William ^a,b,c   Wu, Samuel S ^d   Tomita, Machiko R ^e  

^a UNIVERSITY OF FLORIDA   (United States)

^b Department of Occupational Therapy ^*  (United States)

^c Program in Rehabilitation Science

^d UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY AT BUFFALO   (United States)

Author keywords

Instrumental activities of daily living; Medication management; Older adults

Indexed keywords

ANALGESIC AGENT; ANTIBIOTIC AGENT; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CARDIOVASCULAR AGENT; CENTRAL NERVOUS SYSTEM AGENTS; DIURETIC AGENT; GASTROINTESTINAL AGENT; HORMONE; HORMONE DERIVATIVE; MINERAL; RESPIRATORY TRACT AGENT; SPASMOLYTIC AGENT; THYROID HORMONE; VITAMIN;

ADULT; AGE; AGED; ARTICLE; CHRONIC DISEASE; COGNITION; CONFIDENCE INTERVAL; DAILY LIFE ACTIVITY; FEMALE; FUNCTIONAL ASSESSMENT; GENDER; HEALTH STATUS; HIGH RISK POPULATION; HOME; HUMAN; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL THERAPY; POLYPHARMACY; QUALITY OF LIFE; SEX DIFFERENCE; STATISTICAL MODEL; UNITED STATES;

EID: 19944423137     PISSN: 15394492     EISSN: None     Source Type: Journal    
DOI: 10.1177/153944920402400405     Document Type: Article

References (51)

1. Administration on Aging. (2000). Percent of persons 60+ by race and Hispanic origin by state. Washington, DC: Author. Retrieved January 31, 2004, from http://www.aoa.gov/prof/Statistics/ Census2000/2000pop/percent60plusxrace- HO.asp.
2. Administration on Aging. (2002). A profile of older Americans: 2002. Washington, DC: Author. Retrieved on January 31, 2004, from http://www.aoa.gov/ prof/Statistics/profile/7.asp.
3. AdvancePCS Center for Healthier Aging. (2001, Winter). Health improvement report (pp. 1-8). Irving, TX: Author.
4. American Society of Health-System Pharmacists. (2000, December). American Society of Health-System Pharmacists snapshot of medication use in the U.S. research report. Bethesda, MD: Author.
5. Brawn, L. A., & Castleden, C. M. (1990). Adverse drug reactions: An overview of special consideration in the management of the elderly patient. Drug Safety, 5, 421-435.
6. Cadieux, R. J. (1989). Drug interactions in the elderly: How multiple drug use increases risks exponentially. Postgraduate Medicine, 86, 179-186.
7. Cameron, K., Richardson, A., & Werner, A. (2000/2001). A guide to medication and aging. Generations, 24(4), 8-21.
8. Carr, A. J., Higginson, I. J., & Robinson, P. G. (Eds.). (2003). Quality of life. London, England: BMJ Books.
9. Chutka, D. S., Evans, J. M., Fleming, K. C., & Mikkelson, K. G. (1995). Symposium on Geriatrics: Part One. Drug prescribing for elderly patients. Mayo Clinic Proceedings, 70, 685-693.
10. Cipolle, R. J., Strand, L. M., & Morley, P. C. (1998). Pharmaceutical care practice. New York: McGraw Hill.
11. Clark, F., Azen, S., Zemke, R., Jackson, J., Carlson, M., Mandel, D., et al. (1997). Occupational therapy for independent-living older adults: A randomized controlled trial. Journal of the American Medical Association, 278, 1321-1326.
12. Cook, T. D., & Campbell, D. T. (1979). Quasi-experimentation: Design and analysis issues for field settings. Boston: Houghton Mifflin.
13. Cooper, J. W. (1994). Drug-related problems in the elderly. Generations, 8(2), 11-19.
14. Doble, S. E., & Fisher, A. G. (1998) The dimensionality and validity of the Older Americans Resources and Services (OARS) Activities of Daily Living (ADL) scale. Journal of Outcome Measurement, 2(1), 4-24.
15. Enright, P. L., McBurnie, M. A., Bittner, V., Tracy, R. P., McNamara, R., Arnold, A., et al. (2003). The 6-min walk test: A quick measure of functional status in elderly adults. Chest, 123, 387-398.
16. Falvo, D. R., Holland, B., Brenner, J., & Benshoff, J. J. (1990). Medication use practices in the ambulatory elderly. Health Values: The Journal of Health Behavior, Education, & Promotion, 14(3), 10-17.
17. Flaherty, J. H., Perry, H. M., Lynchard, G. S., & Morley, J. E. (2000). Polypharmacy and hospitalization among home care patients. Journal of Gerontology, 55, M554-M559.
18. Gallagher, L. P. (2001). The potential for adverse drug reactions in elderly patients. Applied Nursing Research, 14, 220-224.
19. Giron, M. S., Wang, H. X., Bernsten, C., Thorslund, M., Winblad, B., & Fastbom, J. (2001). The appropriateness of drug use in the older nondemented and demented population. Journal of the American Geriatrics Society, 49, 277-283.
20. Hanlon, J. T., & Artz, M. B. (2001). Drug-related problems and pharmaceutical care: What are they, do they matter, and what's next? Medical Care, 39, 109-112.
21. Hanlon, J. T., Fillenbaum, G. G., Kuchibhatla, M., Artz, M. B., Boult, C., Gross, C. R., et al. (2002). Impact of inappropriate drug use on mortality and functional status in representative community dwelling elders. Medical Care, 40, 166-176.
22. Hohl, C. M., Dankoff, J., Colacone, A., & Afilalo, M. (2001). Polypharmacy, adverse drug-related events, and potential adverse drug interactions in elderly patients presenting to an emergency department. Annals of Emergency Medicine, 38, 666-671.
23. Hughes, C. M., McElnay, J. C., & Fleming, G. F. (2001). Benefits and risks of self medication. Drug Safety, 24, 1027-1037.
24. Iliffe, S., Haines, A., Gallivan, S., Booroff, A., Goldenberg, E., & Morgan, P. (1991). Assessment of elderly people in general practice: 2. Functional abilities and medical problems. British Journal of General Practitioners, 41(342), 3-5.
25. Kempen, G. I. J., Brilman, E. L., Ranchor, A. V., & Ormel, J. (1999). Morbidity and quality of life and the moderating effects of level of education in the elderly. Social Science and Medicine, 49, 143-149.
26. Klesges, L. M., Pahor, M., Short, R. I., Wan, J. Y., Williamson, J. D., & Guralnik, J. M. (2001). Financial difficulty in acquiring food among elderly disabled women: Results from the Women's Health and Aging Study. American Journal of Public Health, 91, 68-75.
27. Koh, N. Y., & Koo, W. H. (2002). Polypharmacy in palliative care: Can it be reduced? Singapore Medical Journal, 43, 279-283.
28. Law, M., LeClair, L., & Steinwender, S. (1998). Occupation, health and well-being. Canadian Journal of Occupational Therapy, 65, 81-91.
29. Leipzig, R., & Edelberg, H. (2001). Prescribing: Keys to maximizing benefit while avoiding adverse drug effects. Geriatrics, 56, 30-34.
30. Lyder, C., Fennie, K., Chen, C., & Fulmer, T. (2000). Appropriate prescribing for elders: Disease management alone is not enough. Generations, 24(4), 55-59.
31. Mann, W., Karuza, J., Hurren, D., & Tomita, M. (1993). Needs of home-based older persons for assistive devices: The University at Buffalo Rehabilitation Engineering Center on Aging Consumer Assessments Study. Technology and Disability, 2(1), 1-11.
32. Monane, M., Monane, S., & Semla, T. (1997). Optimum medication use in elders: Key to successful aging. Western Journal of Medicine, 167, 233-237.
33. Muraki, T., Nagao, T., & Ishikawa, Y. (2001). A preliminary investigation to explore the effects of daytime physical activity patterns on health-related WOL in healthy community-dwelling elderly subjects. Physical and Occupational Therapy in Geriatrics, 19(2), 51-62.
34. Njegovan, V. Hing, M. M., Mitchell, S. L., & Molnar, F. J. (2001). The hierarchy of functional loss associated with cognitive decline in older persons. Journal of Gerontology A: Behavioral Science Medical Science, 56, M639-M643.
35. Onder, G., Pendone, C., Landi, F., Cesari, M., Della Vedova, C., Bernabei, R., et al. (2002). Adverse drug reactions as cause of hospital admissions: Results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA). Journal of the American Geriatrics Society, 50, 1962-1968.
36. Ottenbacher, K. (1991). Statistical conclusion validity: Multiple inferences in rehabilitation research. American Journal of Physical and Medical Rehabilitation, 70, 317-322.
37. Pollak, N., Rheault, W., & Stoecker, J. L. (1996). Reliability and validity of the FIM for persons aged 80 years and above from a multilevel continuing care retirement community. Archives of Physical Medical Rehabilitation, 77, 1056-1061.
38. Portney, L. G., & Watkins, M. P. (2000). Foundations of clinical research: Applications to practice (2nd ed.). Upper Saddle River, NJ: Prentice Hall Health.
39. Rathore, S. S., Mehta, S. S., Boyko, W. L., Jr., & Schulman, K. A. (1998). Prescription medication use in older Americans: A national report card on prescribing. Family Medicine, 30, 733-739.
40. Rehabilitation Engineering Research Center on Aging Center for Assistive Technology. (2000). Consumer Assessment Study: Evaluating quality of life of home-based elders with disability. Buffalo, NY: State University of New York at Buffalo.
41. Reuben, D. B., Valle, L. A., Hays, R. D., & Siu, A. L. (1995). Measuring physical function in community-dwelling older persons: A comparison of self-administered, interviewer-administered, and performance-based measures. Journal of the American Geriatrics Society, 43, 17-23.
42. Rogers, J. C., & Holm, M. B. (1998). Evaluation of occupational performance areas. In M. E. Neistadt & E. B. Crepeau (Eds.), Willard and Spaceman's occupational therapy (9th ed., pp. 185-222). Philadelphia: Lippincott, Williams, and Wilkins.
43. Rubin, C. D., Sizemore, M. T., Loftis, P. A., & de Mola, N. L. (1993). A randomized controlled trial of outpatient geriatric evaluation and management in a large public hospital. Journal of the American Geriatrics Society, 41, 1023-1028.
44. Ruiz, J. G., Array, S., & Lowenthal, D. T. (1996). Avoiding over-medication of elderly patients. American Journal of Therapeutics, 3, 784-788.
45. Schmader, K. E., Hanlon, J. T., Fillenbaum, G. C., Huber, M., Pieper, C., & Horner, R. (1998). Medication use patterns among the demented, cognitively impaired and cognitively intact community-dwelling elderly people. Age and Ageing, 27, 493-501.
46. Spina, E., & Scordo, M. (2002). Clinically significant drug interactions with antidepressants in the elderly. Drugs Aging, 19, 299-320.
47. Stuck, A. E., Walthert, J. M., Nikolaus, T., Bula, C. J., Hohmann, C., & Beck, J. C. (1999). Risk factors for functional status decline in community-living elderly people: A systematic literature review. Social Science and Medicine, 48, 445-469.
48. Thomas, V. S., Rockwood, K., & McDowell, I. (1998). Multidimensionality in instrumental and basic activities of daily living. Journal of Clinical Epidemiology, 51, 315-321.
49. U.S. Census Bureau. (2002). Projections of the total resident population by 5-year age groups and sex with special age categories: Middle series, 1999 to 2000. Washington, DC: Author. Retrieved August 16, 2003, from http://www.census.gov/population/ projections/nation/summary/np-t3-a.txt.
50. Veehof, L. J., Stewart, R. E., Meyboom-de Jong, B., & Haaijer-Ruskamp, F. M. (1999). Adverse drug reactions and polypharmacy in the elderly in general practice. European Journal of Clinical Pharmacology, 55, 533-536.
51. Wald, N. J., & Law, M. R. (2003). A strategy to reduce cardiovascular disease by more than 80%. British Medical Journal, 326, 1419.