-
2
-
-
0038449870
-
The stages of drug development and the human genome project: Drug discovery
-
Preskorn SH. The stages of drug development and the human genome project: Drug discovery. J Psychiatr Pract 2000;6:341-4.
-
(2000)
J Psychiatr Pract
, vol.6
, pp. 341-344
-
-
Preskorn, S.H.1
-
3
-
-
32644487797
-
The rationale for and clinical implications of dose-response curves
-
Series of columns published
-
The rationale for and clinical implications of dose-response curves. Series of columns published in the Journal of Psychiatric Practice (www.preskorn.com/column3.html).
-
Journal of Psychiatric Practice
-
-
-
5
-
-
2442640236
-
Classification of neuropsychiatric medications by principal mechanism of action: A meaningful way to anticipate pharmacodynamically mediated drug interactions (Part II)
-
Preskorn SH. Classification of neuropsychiatric medications by principal mechanism of action: A meaningful way to anticipate pharmacodynamically mediated drug interactions (Part II). J Psychiatr Pract 2004;10:177-81.
-
(2004)
J Psychiatr Pract
, vol.10
, pp. 177-181
-
-
Preskorn, S.H.1
-
6
-
-
0038110524
-
Antipsychotic drug development in the prehuman-genome era: A full circle
-
Preskorn SH. Antipsychotic drug development in the prehuman-genome era: A full circle. J Psychiatr Pract 2001;7:209-13.
-
(2001)
J Psychiatr Pract
, vol.7
, pp. 209-213
-
-
Preskorn, S.H.1
-
7
-
-
0029801375
-
Pharmacodynamics and drug action: Concentration-related pharmacodynamic effects of thioridazine and its metabolites in humans
-
Hartigan-Go K, Bateman DN, Nyberg G, et al. Pharmacodynamics and drug action: Concentration-related pharmacodynamic effects of thioridazine and its metabolites in humans. Clin Pharmacol Ther 1996;60:543-53.
-
(1996)
Clin Pharmacol Ther
, vol.60
, pp. 543-553
-
-
Hartigan-Go, K.1
Bateman, D.N.2
Nyberg, G.3
-
8
-
-
0033052403
-
Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current
-
Drolet B, Vincent F, Rail J, et al. Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current. J Pharmacol Exp Ther 1999;288:1261-8.
-
(1999)
J Pharmacol Exp Ther
, vol.288
, pp. 1261-1268
-
-
Drolet, B.1
Vincent, F.2
Rail, J.3
-
9
-
-
0000193336
-
Thioridazine hydrochloride (Mellaril): Its effect on the electrocardiogram and a report of two fatalities with electrocardiographic abnormalities
-
Kelly HG, Fay JE, Laverty SG. Thioridazine hydrochloride (Mellaril): Its effect on the electrocardiogram and a report of two fatalities with electrocardiographic abnormalities. Can Med Assoc J 1963;89:546-54.
-
(1963)
Can Med Assoc J
, vol.89
, pp. 546-554
-
-
Kelly, H.G.1
Fay, J.E.2
Laverty, S.G.3
-
10
-
-
0014005168
-
The effect of thioridazine hydrochloride and chlorpromazine on the electrocardiogram
-
Huston JR, Bell GE. The effect of thioridazine hydrochloride and chlorpromazine on the electrocardiogram. JAMA 1966;198:134-8.
-
(1966)
JAMA
, vol.198
, pp. 134-138
-
-
Huston, J.R.1
Bell, G.E.2
-
11
-
-
0013974028
-
Thioridazine (Mellaril)-induced ventricular tachycardia controlled with an artificial pacemaker
-
Schoonmaker FW, Osteen RT, Greenfield JC, Jr. Thioridazine (Mellaril)-induced ventricular tachycardia controlled with an artificial pacemaker. Ann Intern Med 1966;65:1076-8.
-
(1966)
Ann Intern Med
, vol.65
, pp. 1076-1078
-
-
Schoonmaker, F.W.1
Osteen, R.T.2
Greenfield Jr., J.C.3
-
12
-
-
84856358274
-
Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs
-
Fowler NO, McCall D, Chou TC, et al. Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs. Am J Cardiol 1976;37:223-30.
-
(1976)
Am J Cardiol
, vol.37
, pp. 223-230
-
-
Fowler, N.O.1
McCall, D.2
Chou, T.C.3
-
13
-
-
0020575732
-
Thioridazine-induced torsade de pointes: Successful therapy with isoproterenol
-
Kemper AJ, Dunlap R, Pietro DA. Thioridazine-induced torsade de pointes: Successful therapy with isoproterenol. JAMA 1983;249:2931-4.
-
(1983)
JAMA
, vol.249
, pp. 2931-2934
-
-
Kemper, A.J.1
Dunlap, R.2
Pietro, D.A.3
-
15
-
-
0028198351
-
Complete heart block and torsade de pointes associated with thioridazine poisoning
-
Hulisz DT, Dasa SL, Black LD, et al. Complete heart block and torsade de pointes associated with thioridazine poisoning. Pharmacotherapy 1994;14:239-45.
-
(1994)
Pharmacotherapy
, vol.14
, pp. 239-245
-
-
Hulisz, D.T.1
Dasa, S.L.2
Black, L.D.3
-
16
-
-
0036263960
-
Thioridazine and sudden death in psychiatric in-patients
-
Reilly JG, Avis SA, Ferrier IN, et al. Thioridazine and sudden death in psychiatric in-patients. Br J Psychiatry 2002;180:515-22.
-
(2002)
Br J Psychiatry
, vol.180
, pp. 515-522
-
-
Reilly, J.G.1
Avis, S.A.2
Ferrier, I.N.3
-
17
-
-
0032699804
-
Pharmacokinetic interaction of fluvoxamine and thioridazine in schizophrenic patients
-
Carrillo JA, Ramos SI, Herraiz AG, et al. Pharmacokinetic interaction of fluvoxamine and thioridazine in schizophrenic patients. J Clin Psychopharmacol 1999;19:494-9.
-
(1999)
J Clin Psychopharmacol
, vol.19
, pp. 494-499
-
-
Carrillo, J.A.1
Ramos, S.I.2
Herraiz, A.G.3
-
18
-
-
0003155654
-
Antidepressants
-
Levy RH, Thummel KE, Trager WF, et al. Philadelphia: Lippincott, Williams & Wilkins
-
Shad MU, Preskorn SH. Antidepressants. In: Levy RH, Thummel KE, Trager WF, et al., eds. Metabolic drug interactions. Philadelphia: Lippincott, Williams & Wilkins; 2000: 563-77.
-
(2000)
Metabolic Drug Interactions
, pp. 563-577
-
-
Shad, M.U.1
Preskorn, S.H.2
-
19
-
-
0031025875
-
Clinically relevant pharmacology of selective serotonin reuptake inhibitors: An overview with emphasis on pharmacokinetics and effects on oxidative drug metabolism
-
Preskorn SH. Clinically relevant pharmacology of selective serotonin reuptake inhibitors: An overview with emphasis on pharmacokinetics and effects on oxidative drug metabolism. Clin Pharmacokinet 1997;32(Suppl 1):1-21.
-
(1997)
Clin Pharmacokinet
, vol.32
, Issue.SUPPL. 1
, pp. 1-21
-
-
Preskorn, S.H.1
-
20
-
-
0037773113
-
Fatal drug-drug interactions as a differential consideration in apparent suicides
-
Preskorn SH. Fatal drug-drug interactions as a differential consideration in apparent suicides. J Psychiatr Pract 2002;8:233-8.
-
(2002)
J Psychiatr Pract
, vol.8
, pp. 233-238
-
-
Preskorn, S.H.1
-
21
-
-
0038787512
-
Clinical pharmacology case conference: A suicide attempt?
-
Preskorn SH. Clinical pharmacology case conference: A suicide attempt? J Psychiatr Pract 2002;8:306-10.
-
(2002)
J Psychiatr Pract
, vol.8
, pp. 306-310
-
-
Preskorn, S.H.1
-
22
-
-
0030921915
-
Fatality associated with combined fluoxetine-amitriptyline therapy
-
Preskorn SH, Baker B. Fatality associated with combined fluoxetine-amitriptyline therapy (letter). JAMA 1997;277:682.
-
(1997)
JAMA
, vol.277
, pp. 682
-
-
Preskorn, S.H.1
Baker, B.2
-
23
-
-
16344365275
-
Drug-drug interactions: Proof of relevance (Part I)
-
Preskorn SH. Drug-drug interactions: Proof of relevance (Part I). J Psychiatr Pract 2005;11:116-22.
-
(2005)
J Psychiatr Pract
, vol.11
, pp. 116-122
-
-
Preskorn, S.H.1
-
24
-
-
32644454752
-
The case studies section
-
Series of columns published
-
The case studies section. Series of columns published in the Journal of Psychiatric Practice (can be accessed at www .preskorn.com/column1.html).
-
Journal of Psychiatric Practice
-
-
-
25
-
-
0038276038
-
Reproducibility of the in vivo effect of the selective serotonin reuptake inhibitors on the in vivo function of cytochrome P450 2D6: An update (part I)
-
Preskorn SH. Reproducibility of the in vivo effect of the selective serotonin reuptake inhibitors on the in vivo function of cytochrome P450 2D6: An update (part I). J Psychiatr Pract 2003;9:150-8.
-
(2003)
J Psychiatr Pract
, vol.9
, pp. 150-158
-
-
Preskorn, S.H.1
-
26
-
-
0038311587
-
Reproducibility of the in vivo effect of the selective serotonin reuptake inhibitors on the in vivo function of cytochrome P450 2D6: An update (part II)
-
Preskorn SH. Reproducibility of the in vivo effect of the selective serotonin reuptake inhibitors on the in vivo function of cytochrome P450 2D6: An update (part II). J Psychiatr Pract 2003;9:228-36.
-
(2003)
J Psychiatr Pract
, vol.9
, pp. 228-236
-
-
Preskorn, S.H.1
-
27
-
-
19244365446
-
Oral erythromycin and the risk of sudden death from cardiac causes
-
Ray WA, Murray KT, Meredith S, et al. Oral erythromycin and the risk of sudden death from cardiac causes. N Engl J Med 2004;351:1089-96.
-
(2004)
N Engl J Med
, vol.351
, pp. 1089-1096
-
-
Ray, W.A.1
Murray, K.T.2
Meredith, S.3
-
28
-
-
0029897864
-
Plasma levels of the enantiomers of thioridazine, thioridazine 2-sulfoxide, thioridazine 2-sulfone, and thioridazine 5-sulfoxide in poor and extensive metabolizers of dextromethorphan and mephenytoin
-
Eap CB, Guentert TW, Schaublin-Loidl M, et al. Plasma levels of the enantiomers of thioridazine, thioridazine 2-sulfoxide, thioridazine 2-sulfone, and thioridazine 5-sulfoxide in poor and extensive metabolizers of dextromethorphan and mephenytoin. Clin Pharmacol Ther 1996;59:322-31.
-
(1996)
Clin Pharmacol Ther
, vol.59
, pp. 322-331
-
-
Eap, C.B.1
Guentert, T.W.2
Schaublin-Loidl, M.3
-
29
-
-
0032756170
-
Effects of selective cytochrome P-450 inhibitors on the metabolism of thioridazine: In vitro studies
-
Daniel WA, Syrek M, Haduch A. Effects of selective cytochrome P-450 inhibitors on the metabolism of thioridazine: In vitro studies. Pol J Pharmacol 1999;51:435-42.
-
(1999)
Pol J Pharmacol
, vol.51
, pp. 435-442
-
-
Daniel, W.A.1
Syrek, M.2
Haduch, A.3
-
30
-
-
0036787071
-
The contribution of cytochrome P-450 isoenzymes to the metabolism of phenothiazine neuroleptics
-
Daniel WA, Syrek M, Haduch A. The contribution of cytochrome P-450 isoenzymes to the metabolism of phenothiazine neuroleptics. Eur Neuropsychopharmacol 2002;12:371-7.
-
(2002)
Eur Neuropsychopharmacol
, vol.12
, pp. 371-377
-
-
Daniel, W.A.1
Syrek, M.2
Haduch, A.3
-
31
-
-
0038469903
-
Thioridazine steady-state plasma concentrations are influenced by tobacco smoking and CYP2D6, but not by the CYP2C9 genotype
-
Berecz R, de la Rubia A, Dorado P, et al. Thioridazine steady-state plasma concentrations are influenced by tobacco smoking and CYP2D6, but not by the CYP2C9 genotype. Eur J Clin Pharmacol 2003;59:45-50.
-
(2003)
Eur J Clin Pharmacol
, vol.59
, pp. 45-50
-
-
Berecz, R.1
De La Rubia, A.2
Dorado, P.3
-
32
-
-
1642579574
-
A randomized evaluation of the effects of six antipsychotic agents on QTc, in the absence and presence of metabolic inhibition
-
Harrigan EP, Miceli JJ, Anziano R, et al. A randomized evaluation of the effects of six antipsychotic agents on QTc, in the absence and presence of metabolic inhibition. J Clin Psychopharmacol 2004;24:62-9.
-
(2004)
J Clin Psychopharmacol
, vol.24
, pp. 62-69
-
-
Harrigan, E.P.1
Miceli, J.J.2
Anziano, R.3
-
33
-
-
0036073564
-
Cytochrome p450 phenotyping/genotyping in patients receiving antipsychotics: Useful aid to prescribing?
-
Dahl ML. Cytochrome p450 phenotyping/genotyping in patients receiving antipsychotics: Useful aid to prescribing? Clin Pharmacokinet 2002;41:453-70.
-
(2002)
Clin Pharmacokinet
, vol.41
, pp. 453-470
-
-
Dahl, M.L.1
-
34
-
-
0035525466
-
The major fluvoxamine metabolite in urine is formed by CYP2D6
-
Spigset O, Axelsson S, Norstrom A, et al. The major fluvoxamine metabolite in urine is formed by CYP2D6. Eur J Clin Pharmacol 2001;57:653-8.
-
(2001)
Eur J Clin Pharmacol
, vol.57
, pp. 653-658
-
-
Spigset, O.1
Axelsson, S.2
Norstrom, A.3
-
35
-
-
0038096791
-
Effects of the CYP 2D6 genotype and cigarette smoking on the steady-state plasma concentrations of fluvoxamine and its major metabolite fluvoxamino acid in Japanese depressed patients
-
Gerstenberg G, Aoshima T, Fukasawa T, et al. Effects of the CYP 2D6 genotype and cigarette smoking on the steady-state plasma concentrations of fluvoxamine and its major metabolite fluvoxamino acid in Japanese depressed patients. Ther Drug Monit 2003;25:463-8.
-
(2003)
Ther Drug Monit
, vol.25
, pp. 463-468
-
-
Gerstenberg, G.1
Aoshima, T.2
Fukasawa, T.3
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