Structure and solid-state chemistry of anhydrous and hydrated crystal forms of the trimethoprim-sulfamethoxypyridazine 1:1 molecular complex

Journal of Pharmaceutical Sciences

Volumn 89, Issue 4, 2000, Pages 478-489

  Bettinetti, Giampiero ^a   Caira, Mino R ^b   Callegari, Athos ^a   Merli, Marcello ^a   Sorrenti, Milena ^a   Tadini, Carla ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Anhydrous and hydrated crystal forms; Anhydrous hydrate interconversion; Computer generated x ray powder patterns; Crystal structure; Mechanical activation; Metastable eutectic; Thermal anlysis; Trimethoprim sulfamethoxypyridazine molecular complex

Indexed keywords

SULFAMETHOXYPYRIDAZINE; TRIMETHOPRIM;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DRUG FORMULATION; DRUG GRANULATION; DRUG STABILITY; DRUG STRUCTURE; HYDROGEN BOND; SOLID STATE; STRUCTURE ANALYSIS; THERMAL ANALYSIS;

EID: 0033812553     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6017(200004)89:4<478::AID-JPS5>3.0.CO;2-5     Document Type: Article

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