Characterization of CD8+ T cells and microenvironment in oral lesions of human immunodeficiency virus-infected persons with oropharyngeal candidiasis

Infection and Immunity

Volumn 73, Issue 6, 2005, Pages 3659-3667

  McNulty, Kelly M ^a   Plianrungsi, Jananya ^a   Leigh, Janet E ^a   Mercante, Donald ^a   Fidel Jr , Paul L ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADDRESSIN; ANTIRETROVIRUS AGENT; CD4 ANTIGEN; CD8 ANTIGEN; CELL ADHESION MOLECULE; DIMER; HOMING RECEPTOR; INTEGRIN; MESSENGER RNA; PROTEINASE INHIBITOR; RNA; T LYMPHOCYTE RECEPTOR; UVOMORULIN;

ARTICLE; CANDIDIASIS; CONTROLLED STUDY; FLOW CYTOMETRY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE MIGRATION; MAJOR CLINICAL STUDY; MICROENVIRONMENT; MOUTH LESION; OROPHARYNX; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

CANDIDIASIS, ORAL; CD8-POSITIVE T-LYMPHOCYTES; CELL ADHESION MOLECULES; HIV INFECTIONS; HUMANS; INTEGRINS; MOUTH MUCOSA; PHARYNGEAL DISEASES; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA;

EID: 19744375842     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.6.3659-3667.2005     Document Type: Article

References (46)

1. Allen, C. M., A. Saffer, R. K. Meister, F. M. Beck, and S. Bradway. 1994. Comparison of a lesion-inducing isolate and a non-lesional isolate of Candida albicans in an immunosuppressed rat model of oral candidiasis. J. Oral Pathol. Med. 23:133-139.
2. Ashman, R. B., C. S. Farah, S. Wanasaengsakul, Y. Hu, G. Pang, and R. Clancy. 2004. Innate versus adaptive immunity in Candida albicans infection. Immunol. Cell Biol. 82:196-204.
3. + cells also demonstrate stain-specific immunopathological effects. Microbiology 145:1631-1640.
4. Bos, J. D., M. B. Teunissen, I. Cairo, S. R. Krieg, M. L. Kapsenberg, P. K. Das, and J. Borst. 1990. T-cell receptor gamma delta bearing cells in normal human skin. J. Investig. Dermatol. 94:37-42.
5. Camerini, V., C. Panwala, and M. Kronenberg. 1993. Regional specialization of the mucosal immune system. J. Immunol. 151:1765-1775.
6. 7 integrin. Nature 372:190-193.
7. Chakir, J., L. Cote, C. Coulombe, and N. Deslauriers. 1994. Differential pattern of infection and immune response during experimental oral candidiasis in BALB/c and DBA/2 (H-2d) mice. Oral Microbiol. Immunol. 9:88-94.
8. Clift, R. A. 1984. Candidiasis in the transplant patient. Am. J. Med. 77(Suppl. 4D):34-38.
9. Deslauriers, N., L. Cote, S. Montplaisir, and L. De Repentigny. 1997. Oral carriage of Candida albicans in murine AIDS. Infect. Immun. 65:661-667.
10. Dodd, C. L., D. Greenspan, M. H. Katz, J. L. Westenhouse, D. W. Feigal, and J. S. Greenspan. 1991. Oral candidiasis in HIV infection: pseudomembranous and erythematous candidiasis show similar rates of progression to AIDS. AIDS 5:1339-1343.
11. + T lymphocytes in recovery from oropharyngeal candidiasis. Infect. Immun. 70:724-731.
12. Farah, C. S., S. Elahi, G. Pang, T. Gotjamanos, G. J. Seymour, R. L. Clancy, and R. B. Ashman. 2001. T Cells augment monocyte and neutrophil function in host resistance against oropharyngeal candidiasis. Infect. Immun. 69:6110-6118.
13. Fichtenbaum, C. J., and W. Powderly. 1998. Refractory mucosal candidiasis in patients with human immunodeficiency virus infection. Clin. Infect. Dis. 26:556-565.
14. Fidel, P. L., Jr. 2002. Distinct protective host defenses against oral and vaginal candidiasis. Med. Mycol. 40:359-375.
15. Fidel, P. L., Jr., N. A. Wolf, and M. A. KuKuruga. 1996. T lymphocytes in the murine vaginal mucosa are phenotypically distinct from those in the periphery. Infect. Immun. 64:3793-3799.
16. Fischer, A., J. J. Ballet, and C. Griscelli. 1978. Specific inhibition of in vitro Candida-induced lymphocyte proliferation by polysaccharide antigens present in serum of patients with chronic mucocutaneous candidiasis. J. Clin. Investig. 62:1005-1013.
17. Fisher-Hoch, S. P., and L. Hutwagner. 1995. Opportunistic candidiasis: an epidemic of the 1980s. Clin. Infect. Dis. 21:897-904.
18. Greenspan, J. S., C. E. Barr, J. J. Sciubba, and J. R. Winkler. 1992. Oral manifestations of HIV infection: definitions, diagnostic criteria and principles of therapy. Oral Surg. Oral Med. Oral Pathol. 73:142-144.
19. Hogg, N., and C. Berlin. 1995. Structure and function of adhesion receptors in leukocyte trafficking. Immunol. Today 16:327-330.
20. Imam, N., C. C. J. Carpenter, K. H. Mayer, A. Fisher, M. Stein, and S. B. Danforth. 1990. Hierarchical pattern of mucosal Candida infections in HIV-seropositive women. Am. J. Med. 89:142-146.
21. Klein, R. S., C. A. Harris, C. B. Small, B. Moll, M. Lesser, and G. H. Friedland. 1984. Oral candidiasis in high-risk patients as the initial manifestation of the acquired immunodeficiency syndrome. N. Engl. J. Med. 311:354-357.
22. Knight, L., and J. Fletcher. 1971. Growth of Candida albicans in saliva: stimulation by glucose associated with antibiotics, corticosteriods and diabetes mellitus. J. Infect. Dis. 123:371-377.
23. Laskaris, G., M. Hadjivassiliou, and J. Stratigos. 1992. Oral signs and symptoms in 160 Greek HIV-infected patients. J. Oral Pathol. Med. 21:120-123.
24. Lefrancois, L. 1991. Extrathymic differentiation of intraepithelial lymphocytes: generation of a separate and unequal T-cell repertoire? Immunol. Today 12:436-438.
25. Leigh, J. E., M. Barousse, R. K. Swoboda, T. Myers, S. Hager, N. A. Wolf, J. L. Cutright, J. Thompson, J. D. Sobel, and P. L. Fidel, Jr. 2001. Candida-specific systemic cell-mediated immune reactivities in HIV-infected persons with and without mucosal candidiasis. J. Infect. Dis. 183:277-285.
26. Leigh, J. E., C. Steele, F. L. Wormley, Jr., W. Luo, R. A. Clark, W. Gallaher, and P. L. Fidel, Jr.1998. Th1/Th2 cytokine expression in saliva of HIV-positive and HIV-negative individuals: a pilot study in HIV-positive individuals with oropharyngeal candidiasis. J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 19:373-380.
27. Macher, A. M. 1988. The pathology of AIDS. Public Health Rep. 103:246-254.
28. Myers, T. A., J. E. Leigh, A. Arribas, S. Hager, R. A. Clark, E. Lilly, and P. L. Fidel, Jr. 2003. Immunohistochemical evaluation of T cells in oral lesions from human immunodeficiency virus-positive persons with oropharyngeal candidiasis. Infect. Immun. 71:956-963.
29. Nagai, Y., N. Takeshita, and T. Saku. 1992. Histopathologic and ultrastructural studies of oral mucosa with Candida infection. J. Oral. Pathol. Med. 21:171-175.
30. Nandi, D., and J. P. Allison. 1991. Phenotypic analysis and gamma/delta-T cell receptor repertoire of murine T cells associated with the vaginal epithelium. J. Immunol. 147:1773-1778.
31. Odds, F. C. 1988. Chronic mucocutaneous candidosis, p. 104-110. In Candida and candidosis. University Park Press, Baltimore, MD.
32. - skin intraepithelial lymphocytes in radiation bone marrow chimeras. J. Immunol. 151:3000-3006.
33. Patton, L. L., R. G. McKaig, R. P. Strauss, and J. J. Enron. 1998. Oral manifestations of HIV in a southeast USA population. Oral Dis. 4:164-169.
34. Reichart, P. A., L. P. Samaranayake, and H. P. Philipsen. 2000. Pathology and clinical correlates in oral candidiasis and its variants: a review. Oral Dis. 6:85-91.
35. Rocha, B., P. Vassalli, and D. Guy-Grand. 1994. Thymic and extrathymic origins of gut intraepithelial lymphocyte populations in mice. J. Exp. Med. 180:681-686.
36. Romagnoli, P., N. Pimpinelli, M. Mori, P. A. Reichart, L. R. Eversole, and G. Ficarra. 1997. Immunocompetent cells in oral candidiasis of HIV-infected patients: an immunohistochemical and electron microscopical study. Oral Dis. 3:99-105.
37. Romani, L., S. Mocci, C. Bietta, L. Lanfaloni, P. Puccetti, and F. Bistoni. 1991. Th1 and Th2 cytokine secretion patterns in murine candidiasis: association of Th1 responses with acquired resistance. Infect. Immun. 59:4647-4654.
38. Salmi, M., and S. Jalkanen. 1997. How do lymphocytes know where to go: current concepts and enigmas of lymphocyte homing. Adv. Immunol. 64:139-218.
39. Samaranayake, L. P. 1992. Oral mycoses in HIV infection. Oral Surg. Oral Med. Oral Pathol. 73:171-180.
40. Samaranayake, Y. H., and L. P. Samaranayake. 2001. Experimental oral candidiasis in animal models. Clin. Microbiol. Rev. 14:398-429.
41. Schiavon, V., P. Roth, W. E. Bolton, J. P. Farcet, A. Bensussan, and L. Boumsell. 1996. Lymphocytes subsets in normal individuals: analysis by four color immunofluorescence and flow cytometry on whole blood. Tissue Antigens 48:312-318.
42. Slavinsky, J., III, T. Myers, R. K. Swoboda, J. E. Leigh, S. Hager, and P. L. Fidel, Jr.2002. Th1/Th2 cytokine profiles in saliva of HIV-positive smokers with oropharyngeal candidiasis. Oral Microbiol. Immunol. 17:38-43.
43. Steele, C., J. E. Leigh, R. K. Swoboda, and P. L. Fidel, Jr.2000. Growth inhibition of Candida by human oral epithelial cells. J. Infect. Dis. 182:1479-1485.
44. Terres, A. M., J. M. Pajares, D. O'Toole, S. Ahern, and D. Kelleher. 1998. H. pylori infection is associated with downregulation of E-cadherin, a molecule involved in epithelial cell adhesion and proliferation control. J. Clin. Pathol. 51:410-412.
45. Wormley, F. L., Jr., J. Chaiban, and P. L. Fidel, Jr.2001. Cell adhesion molecule and lymphocyte activation marker expression during experimental vaginal candidiasis. Infect. Immun. 69:5072-5079.
46. Wozniak, K. L., J. E. Leigh, S. Hager, R. K. Swoboda, and P. L. Fidel, Jr.2002. A comprehensive study of Candida-specific antibodies in saliva of HIV-infected persons with oropharyngeal candidiasis. J. Infect. Dis. 185:1269-1276.