Rational design of highly potent HIV-1 fusion inhibitory proteins: Implication for developing antiviral therapeutics

Biochemical and Biophysical Research Communications

Volumn 332, Issue 3, 2005, Pages 831-836

  Ni, Ling ^a,b   Gao, George F ^a   Tien, Po ^a  

^a INSTITUTE OF MICROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

gp41; Heptad repeat regions; HIV 1 fusion inhibitors; Protein inhibitors

Indexed keywords

ANTIVIRUS AGENT; HUMAN IMMUNODEFICIENCY VIRUS 1 FUSION INHIBITORY PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS FUSION INHIBITOR; PROTEIN HR 212; PROTEIN HR121; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG POTENCY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IC 50; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; ANTI-HIV AGENTS; DRUG DESIGN; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMANS; MEMBRANE FUSION; MOLECULAR SEQUENCE DATA; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS; VIRAL FUSION PROTEINS;

EID: 19744363341     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.05.037     Document Type: Article

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