Stereoselective synthesis of methyl (Z)-(4,4-difluoro-2,3,4,5-tetrahydro- 1H-1-benzazepin-5-ylidene)acetate using a dianion Horner-Wadsworth-Emmons reagent

Chemical and Pharmaceutical Bulletin

Volumn 53, Issue 5, 2005, Pages 589-590

  Shimada, Yoshiaki ^a   Akane, Hiroaki ^a   Taniguchi, Nobuaki ^a   Matsuhisa, Akira ^a   Kawano, Noriyuki ^a   Tanaka, Akihiro ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Arginine vasopressin antagonist; Dianion; Horner Wadsworth Emmons reaction

Indexed keywords

ARGIPRESSIN; ARGIPRESSIN DERIVATIVE; BENZAZEPINE DERIVATIVE; METHYL (Z) (4,4 DIFLUORO 2,3,4,5 TETRAHYDRO 1H 1 BENZAZEPIN 5 YLIDENE)ACETATE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; HORNER WADSWORTH EMMONS REACTION; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; SYNTHESIS;

ACETATES; BENZAZEPINES; STEREOISOMERISM; TECHNOLOGY, PHARMACEUTICAL;

EID: 19644379621     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.53.589     Document Type: Article

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