Intermolecular conformational coupling and free energy exchange enhance the catalytic efficiency of cardiac muscle SERCA2a following the relief of phospholamban inhibition

Biochemistry

Volumn 44, Issue 21, 2005, Pages 7713-7724

  Mahaney, James E ^a   Albers, R Wayne ^b   Waggoner, Jason R ^c   Kutchai, Howard C ^d   Froehlich, Jeffrey P ^e  

^a EDWARD VIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF VIRGINIA   (United States)

^e UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC MUSCLE; INTERMOLECULAR CONFORMATIONAL COUPLING; PHOSPHOLAMBAN (PLB); PHOSPHORYLATION;

CATALYSIS; CELLS; CHEMICAL ACTIVATION; CONFORMATIONS; FREE ENERGY; KINETIC THEORY; OLIGOMERS;

MUSCLE;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CALCIUM; CYCLIC AMP; EGTAZIC ACID; HEART ENZYME; PHOSPHOLAMBAN; PROTEIN SERCA2A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CALCIUM TRANSPORT; CATALYSIS; CONFORMATION; ENERGY TRANSFER; ENZYME ACTIVATION; ENZYME INHIBITION; HEART MUSCLE; HYDROLYSIS; INSECT CELL; KINETICS; MATHEMATICAL ANALYSIS; MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; RABBIT; SARCOPLASMIC RETICULUM; STEADY STATE;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIBODIES, MONOCLONAL; CALCIUM; CALCIUM RADIOISOTOPES; CALCIUM-BINDING PROTEINS; CALCIUM-TRANSPORTING ATPASES; CATALYSIS; CELL LINE; DOGS; EGTAZIC ACID; ENZYME ACTIVATION; INTRACELLULAR MEMBRANES; ISOENZYMES; MOTHS; MUSCLE, SKELETAL; MYOBLASTS, CARDIAC; MYOCARDIUM; PHOSPHORYLATION; PROTEIN CONFORMATION; RABBITS; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THERMODYNAMICS;

INSECTA;

EID: 19644369427     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048011i     Document Type: Article

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