Synthesis, in vivo and in vitro biological activity of novel azaline B analogs

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 11, 2005, Pages 2894-2897

  Samant, Manoj P ^a   Gulyas, Jozsef ^a   Hong, Doley J ^b   Croston, Glenn ^b   Rivier, Catherine ^a   Rivier, Jean ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b Ferring Pharmaceuticals AS   (Denmark)

Author keywords

Azaline B; Degarelix; GnRH antagonists; Structure activity relationships

Indexed keywords

AZALINE B DERIVATIVE; GONADORELIN ANTAGONIST; LUTEINIZING HORMONE; UNCLASSIFIED DRUG;

ARTICLE; CASTRATION; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; HORMONE INHIBITION; HUMAN; HUMAN CELL; IC 50; MALE; NONHUMAN; RAT;

ANIMALS; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GONADOTROPIN-RELEASING HORMONE; HUMANS; MALE; RATS;

EID: 19544383599     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.03.085     Document Type: Article

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