Oral administration of geranylgeranylacetone blunts the endothelial dysfunction induced by ischemia and reperfusion in the rat heart

Journal of Cardiovascular Pharmacology

Volumn 45, Issue 6, 2005, Pages 555-562

  Zhu, Zhen ^a   Takahashi, Naohiko ^a   Ooie, Tatsuhiko ^a   Shinohara, Tetsuji ^a   Yamanaka, Kunitoshi ^a   Saikawa, Tetsunori ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

Geranylgeranylacetone; Ischemia reperfusion; Isolated rat heart; Nitric oxide; Phosphatidylinositol 3 kinase; Rho kinase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACETYLCHOLINE; ADRENOMEDULLIN; ANTIULCER AGENT; ENDOTHELIN 1; HEAT SHOCK PROTEIN 72; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; RHO KINASE; TEPRENONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DRUG EFFECT; ENDOTHELIUM INJURY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; ISOLATED HEART; LEUKOCYTE ACTIVATION; MALE; NONHUMAN; PERFUSION PRESSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY;

ADMINISTRATION, ORAL; ANIMALS; DITERPENES; ENDOTHELIUM, VASCULAR; MALE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 19544379701     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.fjc.0000159879.04444.22     Document Type: Article

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