Chiral discrimination in binding of enantiomers of 2-(aminoalkoxy)- substituted 4-(2-thienyl)pyrimidines and 4,6-bis(2-thienyl)pyrimidines with duplex DNA

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 11, 2005, Pages 2720-2723

  Strekowski, Lucjan ^a   Cegla, Marek T ^a   Honkan, Vidya ^a   Buczak, Henryk ^a   Winkeljohn, W Rucks ^a   Baumstark, Alfons L ^a   Wilson, W David ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

B DNA; Chirality; Nonclassical intercalators

Indexed keywords

DOUBLE STRANDED DNA; INTERCALATING AGENT; PYRIMIDINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; CHIRALITY; DNA BINDING; DRUG DNA BINDING; DRUG SYNTHESIS; ENANTIOMER; HYDROPHILICITY; HYDROPHOBICITY; MOLECULAR MODEL; PROTON NUCLEAR MAGNETIC RESONANCE;

DNA; MAGNETIC RESONANCE SPECTROSCOPY; PYRIMIDINES; STEREOISOMERISM;

EID: 19544379175     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.04.004     Document Type: Article

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