γ-Butyltelluro-2-butanol: A route to reactive 1,4-dianion intermediates

Tetrahedron Letters

Volumn 46, Issue 26, 2005, Pages 4423-4425

  Princival, Jefferson L ^a   De Barros, Simone M G ^a   Comasseto, João V ^b   Dos Santos, Alcindo A ^b  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

1,4 Dianion and diols; Tellurium lithium exchange

Indexed keywords

ALCOHOL DERIVATIVE; ALDEHYDE DERIVATIVE; ANION; GAMMA BUTYLTELLURO 2 BUTANOL; KETONE DERIVATIVE; LITHIUM; LITHIUM DERIVATIVE; PROTON; TELLURIUM; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; SYNTHESIS;

EID: 19544367557     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.05.002     Document Type: Article

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14. 2) δ (ppm) 251.43
15. -1) was added by means of a dropping funnel. The progress of reaction was monitored by TLC then diluted with water (20 mL) and a mixture of ethyl acetate-hexane 1:1 (50 mL). The phases were separated and the aqueous phase was washed with a mixture of ethyl acetate-hexane (1:1, 2 × 50 mL). The organic phases were combined, dried with magnesium sulfate, filtered and the solvents were removed under reduced pressure. The residue was purified by silica gel chromatography eluting with a mixture of hexane-ethyl acetate (15:1), to give 4-(butyltelluro)butan-2- ol (2) ; yield: 0.89 g, (70%)
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