Assessment of fertility in male rats after extended chemical castration with a GnRH antagonist

AAPS Journal

Volumn 6, Issue 1, 2004, Pages

  D'Souza, Susan S ^a   Selmin, Francesca ^b   Murty, Santos B ^c   Qiu, Wei ^a   Thanoo, B C ^d   DeLuca, Patrick P ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF MILAN   (Italy)

^c Murty Pharmaceuticals   (United States)

^d Oakwood Laboratories   (United States)

Author keywords

Chemical castration; GnRH antagonist; Orntide acetate; PLA microspheres; Return to fertility

Indexed keywords

DRUG VEHICLE; GONADORELIN ANTAGONIST; MICROSPHERE; ORNTIDE ACETATE; TESTOSTERONE; UNCLASSIFIED DRUG; DRUG DERIVATIVE; GONADORELIN; MALE CONTRACEPTIVE AGENT;

ANIMAL HOUSING; ARTICLE; BREEDING; CASTRATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG MONITORING; FEMALE; FEMALE FERTILITY; HORMONE INHIBITION; LITTER SIZE; MALE; MALE FERTILITY; NONHUMAN; PROGENY; RAT; STATISTICAL ANALYSIS; SUSTAINED DRUG RELEASE; TESTOSTERONE BLOOD LEVEL; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; FERTILITY; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; CASTRATION; CONTRACEPTIVE AGENTS, MALE; FERTILITY; GONADOTROPIN-RELEASING HORMONE; MALE; RATS; RATS, SPRAGUE-DAWLEY; TESTOSTERONE;

EID: 19544362193     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/ps060110     Document Type: Article

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