Pharmacokinetic changes of DA-7867, a new oxazolidinone, after intravenous and oral administration to rats with short-term and long-term diabetes mellitus induced by streptozotocin

European Journal of Pharmaceutical Sciences

Volumn 25, Issue 2-3, 2005, Pages 337-345

  Bae, Soo K ^a   Yang, Si H ^a   Lee, Shin J ^a   Kwon, Jong W ^b   Kim, Won B ^b   Lee, Duk C ^c   Lee, Myung G ^a  

^a Seoul National University   (South Korea)

^b Dong A Pharmaceutical Company   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

Author keywords

DA 7867; Diabetes mellitus; Pharmacokinetics; Rats; Streptozotocin

Indexed keywords

[N 3 [4 [2 (1 METHYL 5 TETRAZOLYL)PYRIDIN 5 YL] 3 FLUOROPHENYL] 2 OXO 5 OXAZOLIDINYL]METHYLACETAMIDE; DA 7867; OXAZOLIDINONE DERIVATIVE; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DRUG CLEARANCE; DRUG EXCRETION; DRUG HALF LIFE; DRUG TISSUE LEVEL; DRUG URINE LEVEL; KIDNEY CLEARANCE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; URINARY EXCRETION; URINE FLOW RATE;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; DIABETES MELLITUS, EXPERIMENTAL; INJECTIONS, INTRAVENOUS; MALE; METABOLIC CLEARANCE RATE; OXAZOLIDINONES; RATS; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN; TIME FACTORS;

EID: 19444382183     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2005.03.009     Document Type: Article

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