Pharmacokinetic changes of a new carbapenem, DA-1131, after intravenous administration to spontaneously hypertensive rats and deoxycorticosterone acetate-salt-induced hypertensive rats

Drug Metabolism and Disposition

Volumn 27, Issue 6, 1999, Pages 710-716

  Kim, So H ^a   Kim, Won B ^b   Lee, Myung G ^a  

^a Seoul National University   (South Korea)

^b Dong A Pharmaceutical Company   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

6 (1 HYDROXYETHYL) 2 [2 (3 METHANESULFONYLAMINO 1 PROPENYL) 4 PYRROLIDINYLTHIO] 1 METHYL 1 CARBAPEN 2 EM 3 CARBOXYLIC ACID;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CREATININE CLEARANCE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG METABOLISM; DRUG STRUCTURE; DRUG TISSUE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERTENSION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION; URINARY EXCRETION;

ANIMALS; AREA UNDER CURVE; CARBAPENEMS; DESOXYCORTICOSTERONE; DIPEPTIDASES; HALF-LIFE; HYPERTENSION; INJECTIONS, INTRAVENOUS; KIDNEY; LIVER; MALE; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0033054516     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Beilin LT, Wade DN, Honour AJ and Cote TJ (1970) Vascular hyperreactivity with sodium loading and with deoxycorticosterone induced hypertension in the rat. Clin Sci 39:793-810.
2. Campbell BJ, Lin Y-C and Bird ME (1963) Renal aminopeptidase-and copper-activated peptide hydrolysis. J Biol Chem 238:3632-3639.
3. Chiou WL (1978) Critical evaluation of potential error in pharmacokinetic studies using the linear trapezoidal rule method for the calculation of the area under the plasma level-time curve. J Pharmacokinet Biopharm 6:539-546.
4. Chiou WL (1979) New calculation method for mean apparent drug volume of distribution and application to rationale dosage regimens. J Pharm Sci 68:1067-1069.
5. Chiou WL (1980) New calculation method of mean total body clearance of drugs and its application to dosage regimens. J Pharm Sci 69:90-91.
6. Choi SH, Kim GW, Kim JY, Lim GJ, Chung DY, Kim WB and Yang J (1996) Interaction of DA-1131, a new carbapenem antibiotic, with bacterial β-lactamases, in Annual Meeting of the Korea Society of Applied Pharmacology, p 237, Seoul National University, Seoul, South Korea, April 18-19, 1996 (Abstract),.
7. Eatman FB, Colbum WA, Boxenbaum HG, Posmanter HN, Weinfeld RE, Ronfeld R, Weissman L, Moore JD, Gibaldi M and Kaplan SA (1977) Pharmacokinetics of diazepam following multiple dose oral administration to healthy human subjects. J Pharmacokinet Biopharm 5:481-494.
8. Gibaldi M and Perrier D (1982) Pharmacokinetics, 2nd ed., Dekker, New York.
9. Han KS, Lee SH, Lee MG and Kim ND (1993) Pharmacokinetics and pharmacodynamics of bumetanide after intravenous and oral administration to spontaneously hypertensive rats and DOCA-salt-induced hypertensive rats. Biopharm Drug Dispos 14:533-548.
10. Iversen BM and Ofstad J (1987) The effect of hypertension on glomerular structures and capillary permeability in passive Heymann glomerulonephritis. Microvasc Res 34:137-151.
11. Jang SH, Lee MG and Kim ND (1994a) Pharmacokinetics and pharmacodynamics of furosemide after intravenous and oral administration to spontaneously hypertensive rats and DOCA-salt-induced hypertensive rats. Biopharm Drug Dispos 15:185-206.
12. Jang SH, Lee MH and Lee MG (1994b) Pharmacokinetics of acetaminophen after intravenous and oral administration to spontaneously hypertensive rats and normotensive Wistar rats. J Pharm Sci 83:810-814.
13. Kim GW, Chang MS, Lee KW, Chong YS and Yang J (1996a) Comparative in vitro antibacterial activity of DA-1131, a new carbapenem antibiotic (I), in Annual Meeting of the Korea Society of Applied Pharmacology, p 237, Seoul National University, Seoul, South Korea, April 18-19, 1996 (Abstract).
14. Kim SH, Choi YM and Lee MG (1993) Pharmacokinetics and pharmacodynamics of furosemide in protein-calorie malnutrition. J Pharmacokinet Biopharm 21:1-17.
15. Kim JY, Kim GW, Choi SH, We JS, Park HS and Yang J (1996b) Renal dehydropeptidase-1 (DHP-I) stability and pharmacokinetics of DA-1131, a new carbapenem antibiotic, in Annual Meeting of the Korea Society of Applied Pharmacology, Seoul National University, Seoul, South Korea, April 18-19, 1996 (Abstract). p 238.
16. Kim SH, Kim WB, Kwon JW and Lee MG (1999a) Nephroprotective effects of betamipron on a new carbapenem, DA-1131, in rabbits. Biopharm Drug Dispos 20:125-129.
17. Kim SH, Kim WB and Lee MG (1995) Stability, tissue metabolism, tissue distribution, and blood partition of DA-1131, a new carbapenem. Res Commun Mol Pathol Pharmacol 90:347-362.
18. Kim SH, Kim WB and Lee MG (1997a) Pharmacokinetics of a new carbapenem, DA-1131, after intravenous administration to rabbits with endotoxin-induced pyrexia. Res Commun Pharmacol Toxicol 2:121-128.
19. Kim SH, Kim WB and Lee MG (1998a) Interspecies pharmacokinetic scaling of a new carbapenem, DA-1131, in mice, rats, rabbits, and dogs, and prediction of human pharmacokinetics. Biopharm Drug Dispos 19:231-235.
20. Kim SH, Kim WB and Lee MG (1998b) Pharmacokinetics of a new carbapenem, DA-1131, after intravenous administration to rats with alloxan-induced diabetes mellitus. Biopharm Drug Dispos 19:303-308.
21. Kim SH, Kim WB and Lee MG (1998c) No effect of probenecid on the renal handling mechanism of a new carbapenem, DA-1131, in dogs. Res Commun Mol Pathol Pharmacol 101:85-92.
22. Kim SH, Kim WB and Lee MG (1999b) Effect of probenecid on the renal excretion mechanism of a new carbapenem, DA-1131, in rats and rabbits. Antimicrob Agents Chemother 43:96-99.
23. Kim SH, Kwon JW and Lee MG (1998d) Pharmacokinetics and tissue distribution of a new carbapenem, DA-1131, after intravenous administration to mice, rats, rabbits, and dogs. Biopharm Drug Dispos 19:219-229.
24. Kim SH, Kwon JW, Yang J and Lee MG (1997b) Determination of a new carbapenem derivative, DA-1131, in plasma and urine by high-performance liquid chromatography. J Chromatogr B 688:95-99.
25. Kim SH, Shim HJ, Kim WB and Lee MG (1998e) Pharmacokinetics of a new carbapenem, DA-1131, after intravenous administration to rats with uranyl nitrate-induced acute renal failure. Antimicrob Agents Chemother 42:1217-1221.
26. Kropp H, Sundelof JG, Hajdu R and Kahan FM (1982) Metabolism of thienamycin and related carbapenem antibiotics by the renal dipeptidase, dehydropeptidase-I. Antimicrob Agents Chemother 22:62-70.
27. Litterst CL, Mimnaugh EG, Reagan RI and Gram TE (1975) Comparison of in vitro drug metabolism by lung, liver and kidney of several common laboratory species. Drug Metab Dispos 3:259-265.
28. Lowry OH, Rosebrough NJ, Farr AL and Randall RJ (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193:265-275.
29. Mikami H, Ogashiwa M, Saino Y, Inoue M and Mitsuhashi S (1982) Comparative stability of newly introduced β-lactam antibiotics to renal dipeptidase. Antimicrob Agents Chemother 22:693-695.
30. Mouton JW and van den Anker JN (1995) Meropenem clinical pharmacokinetics. Clin Pharmacokinet 28:275-286.
31. Okamoto K and Aoki K (1963) Development of a strain of spontaneously hypertensive rats. Jpn Circ J 27:282-293.
32. Roman RJ, Kaldunski ML, Mattson DL, Mistry M and Nasjletti A (1988) Influence of eicosanoids on renal function of DOCA-salt hypertensive rats. Hypertension 12:287-294.
33. Sakane Y, Berry C, Hopkins MF, Singh K and Ghai RO (1993) Disposition of thiorphan in DOCA-salt and spontaneously hypertensive rats. Res Commun Chem Pathol Pharmacol 81:151-158.
34. Sladek CD and Blair ML (1984) Cholinergic stimulation of vasopressin release in spontaneously hypertensive rats. Hypertension 6:855-860.
35. Yoon EJ, Shim HJ, Lee JJ, Lee SD, Kim WB, Yang J and Lee MG (1997) Pharmacokinetics of DA-125, a new anthracycline, after intravenous administration to spontaneously hypertensive rats, and DOCA-salt-induced hypertensive rats. Drug Metab Dispos 25:66-74.