A sensitive and selective LC-MS-MS method for simultaneous determination of picroside-I and kutkoside (active principles of herbal preparation picroliv) using solid phase extraction in rabbit plasma: Application to pharmacokinetic study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 820, Issue 2, 2005, Pages 221-227

  Vipul, K ^a   Nitin, M ^a   Gupta, R C ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Hepatoprotectant; Kutkoside; LC MS MS; Picroside I; Rabbit plasma

Indexed keywords

BODY FLUIDS; EXTRACTION; IONIZATION; MASS SPECTROMETRY; MONITORING;

ELECTRO-SPRAY IONIZATION; MULTIPLE ELECTRON MONITORING (MEM); RABBIT PLASMA; SOLID PHASE EXTRACTION;

LIQUID CHROMATOGRAPHY;

ACETONITRILE; AMAROGENTIN; KUTKIN; KUTKOSIDE; PICROSIDE I;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; ELECTROSPRAY; EXTRACTION; FLOW RATE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PLASMA; PRIORITY JOURNAL; RABBIT; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION;

ANIMALS; CALIBRATION; CHROMATOGRAPHY, LIQUID; CINNAMATES; GLUCOSIDES; MASS SPECTROMETRY; RABBITS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

ORYCTOLAGUS CUNICULUS;

EID: 19444374103     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.03.032     Document Type: Article

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