Expression of integrin α5β1 and the relationship to collagen and elastin content in human suprarenal and infrarenal aortas

Vascular and Endovascular Surgery

Volumn 39, Issue 3, 2005, Pages 245-251

  Cheuk, Bernice L Y ^a,b   Cheng, Stephen W K ^a,b  

^a Queen Mary Hospital ^*

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; ELASTIN; LIGAND; MATRIX PROTEIN; VERY LATE ACTIVATION ANTIGEN 5; COLLAGEN TYPE 1;

ADULT; AORTA; AORTA MEDIA; ARTERY COMPLIANCE; ARTICLE; CELL DENSITY; DISEASE PREDISPOSITION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFRARENAL AORTA; KIDNEY; MALE; NORMAL HUMAN; ORGAN DONOR; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SMOOTH MUSCLE FIBER; SUPRARENAL AORTA; SURGICAL ANATOMY; WESTERN BLOTTING; ABDOMINAL AORTA; CYTOLOGY; METABOLISM; MIDDLE AGED; SMOOTH MUSCLE;

AORTA, ABDOMINAL; BLOTTING, WESTERN; COLLAGEN TYPE I; ELASTIN; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INTEGRIN ALPHA5BETA1; MALE; MIDDLE AGED; MUSCLE, SMOOTH;

EID: 19444372269     PISSN: 15385744     EISSN: None     Source Type: Journal    
DOI: 10.1177/153857440503900305     Document Type: Article

References (24)

1. Baxter BT, Davis VA, Minion DJ, et al: Abdominal aortic aneurysms are associated with altered matrix proteins of the nonaneurysmal aortic segments. J Vasc Surg 19:797, 1994.
2. Caro CG, Fitz-Gerald JM, Schroter RC: Atheroma and arterial wall shear: Observation, correlation and proposal of a shear dependent mass transfer mechanism for atherogenesis. Proc R Soc Lond B Biol Sci 177: 109-159, 1971.
3. Zarins CK, Giddens DP, Bharadvaj BK, et al: Carotid bifurcation atherosclerosis: Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress. Circ Res 53:502-514, 1983.
4. Lopez-Candales A, Holmes DR, Liao S, et al: Decreased vascular smooth muscle cell density in medial degeneration of human abdominal aortic aneurysms. Am J Pathol 150:993-1007, 1997.
5. Yamamoto K, Yamamoto M: Cell adhesion receptors for native and denatured type I collagens and fibronectin in rabbit arterial smooth muscle cells in culture. Exp Cell Res 214:258-263, 1994.
6. Clyman RI, McDonald KA, Kramer RH: Integrin receptors on aortic smooth muscle cells mediate adhesion to fibronectin, laminin, and collagen. Circ Res 67:175-186, 1990.
7. Hynes RO, Lander AD: Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons. Cell 68:303-322, 1992.
8. Helmer ME: VLA proteins in the integrin family: Structures, functions, and their roles on leukocytes. Ann Rev Immunol 8:365-400, 1990.
9. Nisato RE, Tille JC, Jonczyk A, et al: Alpha v beta 3 and alpha v beta 5 integrin antagonists inhibit angiogenesis in vitro. Angiogenesis 6:105-119, 2003.
10. Zutter MM, Santoro SA, Staatz WD, et al: Re-expression of the α2β1 integrin abrogates the malignant phenotype of breast carcinoma cells. Proc Natl Acad Sci USA 92:7411-7415, 1995.
11. Cheuk BLY, Cheng SWK: Differential expression of integrin α5β1 in human abdominal aortic aneurysm and healthy aortic tissues and its significance in pathogenesis. J Surg Res 15:176-182, 2004.
12. Wassef M, Baxter BT, Chisholm RL, et al: Pathogenesis of abdominal aortic aneurysms: A multidisciplinary research program supported by the National Heart, Lung, and Blood Institute. J Vasc Surg 34:730-738, 2001.
13. Hance KA, Tataria M, Ziporin SJ, et al: Monocyte chemotactic activity in human abdominal aortic aneurysms: Role of elastin degeneration peptides and the 67-kD cell surface elastin receptor. J Vasc Surg 35:254-261, 2002.
14. Huffman MD, Curci JA, Moore G, et al: Functional importance of connective tissue repair during the development of experimental abdominal aortic aneurysms. Surgery 158:429-438, 2000.
15. Kunecki M, Nawrocka A: Elastin-laminin receptor and abdominal aortic aneurysms. New subject to study? A review. Pathol Bio (Paris) 49:333-338, 2001.
16. Lacouture ME, Schaffer JL, Klickstein LB: A comparison of type I collagen, fibronectin, and vitronectin in supporting adhesion of mechanically strained osteoblasts. J Bone Miner Res 17:481-492, 2002.
17. Hynes RO: Integrins: Versatility, modulation, and signaling in cell adhesion. Cell 69:11-24, 1992.
18. Halloran BG, Davis VA, McManus BM, et al: Localization of aortic disease is associated with intrinsic differences in aortic structure. J Surg Res 59:17-22, 1995.
19. Godfrey M, Nejezchleb PA, Schaefer GB, et al: Elastin and fibrillin mRNA and protein levels in the ontogeny of normal human aorta. Connect Tissue Res 29:61-69, 1993.
20. Daugherty A, Cassis LA: Mechanisms of abdominal aortic aneurysm formation. Curr Atheroscler Rep 4:222-227, 2002.
21. Chrysant SG: Vascular remodeling: The role of angiotensin-converting enzyme inhibitors. Am Heart J 135:21-30, 1998.
22. Silver FH: Relationship between hierarchical structure and mechanical properties of the arteries. In: Functional Abnormalities of Aorta, ed. by Boudoulas H, Toutouzas PK, Wooley CF. Armonk, NY: Futura, 1996, pp 133-149.
23. Dobrin PB: Mechanical behavior of vascular smooth muscle in cylindrical segments of arteries in vitro. Ann Biomed Eng 12:497-510, 1984.
24. Clark EA, Brugge JS: Integrin and signal transduction pathways: The road taken. Science 268:233-239, 1995.