Electroneutral K+/H+ exchange in mitochondrial membrane vesicles involves Yol027/Letm1 proteins

Biochimica et Biophysica Acta - Biomembranes

Volumn 1711, Issue 1, 2005, Pages 41-48

  Froschauer, Elisabeth ^a   Nowikovsky, Karin ^a   Schweyen, Rudolf J ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

BCECF; Cation proton exchange; Inner mitochondrial membrane; K+ H+ antiport; PBFI; Submitochondrial particle

Indexed keywords

CARRIER PROTEIN; FLUORESCENT DYE; MAGNESIUM ION; MUTANT PROTEIN; NIGERICIN; POTASSIUM ION; PROTEIN LETM1; PROTEIN YO1027; PROTON; QUININE; UNCLASSIFIED DRUG;

ARTICLE; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GENE; HUMAN VERSUS NONHUMAN DATA; ION EXCHANGE; MEMBRANE TRANSPORT; MEMBRANE VESICLE; MITOCHONDRIAL MEMBRANE; NONHUMAN; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTON TRANSPORT; STOICHIOMETRY; SUBMITOCHONDRIAL PARTICLE; TRANSPORT KINETICS; WILD TYPE; YEAST;

CALCIUM-BINDING PROTEINS; CYTOPLASMIC VESICLES; HYDROGEN; MEMBRANE PROTEINS; MITOCHONDRIA; POTASSIUM; POTASSIUM-HYDROGEN ANTIPORTERS; SACCHAROMYCES CEREVISIAE PROTEINS; YEASTS;

CINCHONA PUBESCENS;

EID: 19444366152     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2005.02.018     Document Type: Article

References (21)

1. E. Blachy-Dyson, and M. Forte VDAC channels IUBMB Life 52 2001 113 118
2. P. Bernardi Mitochondrial transport of cations: channels, exchangers and permeability transition Physiol. Rev. 79 1999 1127 1155
3. + cycle Biochim. Biophys. Acta 1606 2003 23 41
4. + uniports and exchangers J. Bioenerg. Biomembranes 26 1994 519 526
5. P. Mitchell Coupling of phosphorylation to electron and hydrogen transfer by a chemio-osmotic type of mechanism Nature 191 1961 144 148
6. + antiporter by matrix protons J. Biol. Chem. 265 1990 2538 2545
7. + antiport in mitochondria J. Bioenerg. Biomembranes 20 1988 193 209
8. + antiporter from rat liver mitochondria J. Biol. Chem. 265 1990 15316 15322
9. + homeostasis with a potential role in the Wolf-Hirschhorn syndrome J. Biol. Chem. 279 2004 30307 30315
10. K.S. Dimmer, S. Fritz, F. Fuchs, M. Messerschmitt, N. Weinbach, W. Neupert, and B. Westermann Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae Mol. Biol. Cell 13 2002 847 853
11. 2+-binding protein, flanks the Wolf-Hirschhorn syndrome (WHS) critical region and is deleted in most WHS patients Genomics 60 1999 218 225
12. M. Zollino, R. Lecce, R. Fischetto, M. Murdolo, F. Faravelli, A. Selicorni, C. Butte, L. Memo, G. Capovilla, and G. Neri Mapping the Wolf-Hirschhorn syndrome phenotype outside the currently accepted WHS critical region and defining a new critical region, WHSCR-2 Am. J. Hum. Genet. 72 2003 590 597
13. T. Vernet, D. Dignard, and D.Y. Thomas A family of yeast expression vectors containing the phage f1 intergenic region Gene 52 1987 225 233
14. M. Kolisek, G. Zsurka, J. Samaj, J. Weghuber, R.J. Schweyen, and M. Schweigel Mrs2p is an essential component of the major electrophoretic Mg2+ influx system in mitochondria EMBO J. 22 2003 1235 1244
15. T. Brauner, D.F. Hulser, and R.J. Strasser Comparative measurements of membrane potentials with microelectrodes and voltage-sensitive dyes Biochim. Biophys. Acta 771 1984 208 216
16. + antiport activity by hydrogen ions Arch. Biochem. Biophys. 288 1991 358 367
17. + exchange in yeast mitochondria: sensitivity to inhibitors, solubilization and reconstitution of the activity in proteoliposomes Biochim. Biophys. Acta 1108 1992 169 176
18. + antiporters Biochim. Biophys. Acta 1144 1993 367 373
19. + exchanger J. Biol. Chem. 261 1980 1529 1535
20. + transport in rat liver mitochondria J. Biol. Chem. 261 1986 1529 1535
21. + antiporters Arch. Biochem. Biophys. 1988 417 427