Complex Formation and Vectorization of a Phosphorothioate Oligonucleotide with an Amphipathic Leucine- and Lysine-Rich Peptide: Study at Molecular and Cellular Levels

Biopolymers

Volumn 73, Issue 6, 2004, Pages 727-734

  Boukhalfa Heniche, Fatima Zohra ^a,b   Hernández, Belén ^a,b   Gaillard, Stéphane ^a,b   Coïc, Yves Marie ^c   Huynh Dinh, Tam ^c   Lecouvey, Marc ^a,b   Seksek, Olivier ^a,b   Ghomi, Mahmoud ^a,b  

^a CNRS   (France)

^b UNIVERSITÉ PARIS 13   (France)

^c INSTITUT PASTEUR   (France)

Author keywords

Amphipathic peptide; CD; Fluorescence imaging; Peptide nucleic acid interaction; Phosphorothioate oligodeoxynucleotide; Raman scattering; Vectorization

Indexed keywords

BINARY MIXTURES; COMPLEXATION; CONFORMATIONS; FLUORESCENCE; OLIGOMERS; RAMAN SCATTERING; SOLVENTS;

OPTICAL SPECTROSCOPY; VECTORIZATION;

BIOPOLYMERS;

LEUCINE; LYSINE; METHANOL; OLIGONUCLEOTIDE; PEPTIDE; PHOSPHOROTHIOIC ACID; WATER;

ARTICLE; CIRCULAR DICHROISM; COMPLEX FORMATION; CONTROLLED STUDY; FLUORESCENCE; GLIOMA CELL; HUMAN; HUMAN CELL; LIGHT ABSORPTION; PROTEIN CONFORMATION; RAMAN SPECTROMETRY; SOLUBILITY; SPECTROSCOPY;

BIOLOGICAL TRANSPORT; CIRCULAR DICHROISM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LEUCINE; LYSINE; MICROSCOPY, FLUORESCENCE; OLIGONUCLEOTIDES; OLIGOPEPTIDES; PHOSPHORIC ACID ESTERS; SPECTRUM ANALYSIS, RAMAN; THIONUCLEOTIDES; TUMOR CELLS, CULTURED;

EID: 1942499482     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/bip.20018     Document Type: Article

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