Ouabain treatment is associated with upregulation of phosphatase inhibitor-1 and Na+/Ca2+-exchanger and β-adrenergic sensitization in rat hearts

Biochemical and Biophysical Research Communications

Volumn 318, Issue 1, 2004, Pages 219-226

  El Armouche, Ali ^a   Jaeckel, Elmar ^b   Boheler, Kenneth R ^d   Boknik, Peter ^c   Hertle, Boris ^a   Neumann, Joachim ^c   Eschenhagen, Thomas ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c UNIVERSITY OF MÜNSTER   (Germany)

^d NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Adrenergic signaling; Cardiac glycosides; Gene expression; Na+ Ca2+ exchanger; Protein phosphatase inhibitor 1; Rat

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CALCIUM 45; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; MESSENGER RNA; OUABAIN; PHOSPHOLAMBAN; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; RYANODINE RECEPTOR; SODIUM CALCIUM EXCHANGE PROTEIN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DENSITY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG SENSITIVITY; HEART FAILURE; HEART MUSCLE; HEART PAPILLARY MUSCLE; INFUSION; INOTROPISM; MALE; MUSCLE RELAXATION; NONHUMAN; OSMOTIC MINIPUMP; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SENSITIZATION; SIGNAL TRANSDUCTION; UPREGULATION;

ADRENERGIC BETA-AGONISTS; ANIMALS; CALCIUM; CALCIUM-BINDING PROTEINS; CALCIUM-TRANSPORTING ATPASES; CALSEQUESTRIN; CARDIOTONIC AGENTS; CARRIER PROTEINS; ENDORIBONUCLEASES; GTP-BINDING PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOPROTERENOL; MALE; MYOCARDIUM; OUABAIN; PHOSPHOPROTEIN PHOSPHATASE; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA; RECEPTORS, ADRENERGIC, BETA; RNA, MESSENGER; RNA-BINDING PROTEINS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SODIUM-CALCIUM EXCHANGER; UP-REGULATION;

RATTUS NORVEGICUS; STROPHANTHUS GRATUS;

EID: 1942489062     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.04.015     Document Type: Article

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