The fibrinolytic system attenuates vascular tone: Effects of tissue plasminogen activator (tPA) and aminocaproic acid on renal microcirculation

British Journal of Pharmacology

Volumn 141, Issue 6, 2004, Pages 971-978

  Heyman, Samuel N ^a,d   Hanna, Zohair ^a   Nassar, Taher ^a   Shina, Ahuva ^a   Akkawi, Sa'ed ^a   Goldfarb, Marina ^b   Rosen, Seymour ^c   Higazi, Abd Al Roof ^a,d  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b BIKUR CHOLIM HOSPITAL   (Israel)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HEBREW UNIVERSITY   (Israel)

Author keywords

Aminocaproic acid; Calcium; Hemodynamics; Kidney; Laser Doppler; Medulla; Microcirculation; Rat; Reteplase; Tissue plasminogen activator; Vascular smooth muscle

Indexed keywords

ALPHA 2 ANTIPLASMIN; AMINOCAPROIC ACID; ANTIFIBRINOLYTIC AGENT; CALCIUM ION; FIBRINOLYTIC AGENT; PHENYLEPHRINE; PLASMINOGEN ACTIVATOR INHIBITOR 1; RETEPLASE; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE; BLOOD VESSEL TONE; CALCIUM TRANSPORT; CELL CULTURE; CONTROLLED STUDY; FIBRINOLYSIS; HEMODYNAMICS; HUMAN; HUMAN CELL; INTERNALIZATION; KIDNEY BLOOD FLOW; KIDNEY CIRCULATION; KIDNEY CORTEX; KIDNEY MEDULLA; KRINGLE DOMAIN; MICROCIRCULATION; MICROTHROMBUS; MICROVASCULATURE; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR RING; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION; VASODILATATION;

6-AMINOCAPROIC ACID; ANIMALS; AORTA; CALCIUM; CELLS, CULTURED; FIBRINOLYTIC AGENTS; HEMODYNAMIC PHENOMENA; HUMANS; ISOMETRIC CONTRACTION; KIDNEY MEDULLA; MICROCIRCULATION; MUSCLE, SMOOTH, VASCULAR; PERFUSION; PLASMINOGEN INACTIVATORS; RATS; RATS, SPRAGUE-DAWLEY; RENAL CIRCULATION; TISSUE PLASMINOGEN ACTIVATOR; VASOCONSTRICTION;

EID: 1942472516     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705714     Document Type: Article

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