Neuroglial activation in Niemann-Pick Type C mice is suppressed by intracerebral transplantation of bone marrow-derived mesenchymal stem cells

Neuroscience Letters

Volumn 381, Issue 3, 2005, Pages 234-236

  Bae, Jae Sung ^a   Furuya, Shigeki ^b   Ahn, So Jeo ^c   Yi, Seong Joon ^a   Hirabayashi, Yoshio ^b   Jin, Hee Kyung ^a  

^a Kyungpook National University   (South Korea)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^c Kangwon National University   (South Korea)

Author keywords

Astroglia; Bone marrow derived mesenchymal stem cell; Inflammation; Microglia; Niemann Pick Type C disease; Transplantation

Indexed keywords

ANTIBODY; COLONY STIMULATING FACTOR 1; GLIAL FIBRILLARY ACIDIC PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BONE MARROW; BRAIN; CELL ACTIVATION; CELL FUNCTION; CEREBELLUM; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOWN REGULATION; GLIA CELL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MESENCHYMAL STEM CELL TRANSPLANTATION; MICROGLIA; MOUSE; NIEMANN PICK DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT OUTCOME;

ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; MACROPHAGE ACTIVATION; MESENCHYMAL STEM CELL TRANSPLANTATION; MICE; MICE, TRANSGENIC; NEUROGLIA; NIEMANN-PICK DISEASES;

EID: 19344367669     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.02.029     Document Type: Article

References (20)

1. F.C. Barone, and G.Z. Feuerstein Inflammatory mediators and stroke: new opportunities for novel therapeutics J. Cereb. Blood Flow Metab. 19 1999 819 834
2. M. Baudry, Y. Yao, D. Simmons, J. Liu, and X. Bi Postnatal development of inflammation in a murine model of Niemann-Pick type C disease: immunohistochemical observations of microglia and astroglia Exp. Neurol. 184 2003 887 903
3. M. Berry, and A.M. Butt Structure and function of glia in the central nervous system D.I. Graham P.L. Lantos Greenfield's Neuropathology vol. 1 1997 Arnold London 63 79
4. E.D. Carstea, J.A. Morris, K.G. Coleman, S.K. Loftus, D. Zhang, C. Cummings, J. Gu, M.A. Rosenfeld, W.J. Pavan, D.B. Krizman, J. Nagle, M.H. Polymeropoulos, S.L. Sturley, Y.A. Ioannou, M.E. Higgins, M. Comly, A. Cooney, A. Brown, C.R. Kaneski, E.J. Blanchette-Mackie, N.K. Dwyer, E.B. Neufeld, T.Y. Chang, L. Liscum, and D.A. Tagle Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis Science 277 1997 228 231
5. A.M. Depino, C. Earl, E. Kaczmarczyk, C. Ferrari, H. Besedovsky, A. del Rey, F.J. Pitossi, and W.H. Oertel Microglial activation with atypical proinflammatory cytokine expression in a rat model of Parkinson's disease Eur. J. Neurosci. 18 2003 2731 2742
6. A. Fukunaga, K. Uchida, K. Hara, Y. Kuroshima, and T. Kawase Differentiation and angiogenesis of central nervous system stem cells implanted with mesenchyme into ischemic rat brain Cell Transplant. 8 1999 435 441
7. E.C. Hirsch, T. Breidert, E. Rousselet, S. Hunot, A. Hartmann, and P.P. Michel The role of glial reaction and inflammation in Parkinson's disease Ann. N.Y. Acad. Sci. 991 2003 214 228
8. S. Hunot, and E.C. Hirsch Neuroinflammatory processes in Parkinson's disease Ann. Neurol. 53 2003 49 60
9. H.K. Jin, J.E. Carter, G.W. Huntley, and E.H. Schuchman Intracerebral transplantation of mesenchymal stem cells into acid sphingomyelinase-deficient mice delays the onset of neurological abnormalities and extends their life span J. Clin. Invest. 109 2002 1183 1191
10. H.K. Jin, and E.H. Schuchman Ex vivo gene therapy using bone marrow-derived cells: combined effects of intracerebral and intravenous transplantation in a mouse model of Niemann-Pick disease Mol. Ther. 8 2003 876 885
11. O. Lidman, M. Swanberg, L. Horvath, K.W. Broman, T. Olsson, and F. Piehl Discrete gene loci regulate neurodegeneration, lymphocyte infiltration, and major histocompatibility complex class II expression in the CNS J. Neurosci. 23 2003 9817 9823
12. S.K. Loftus, J.A. Morris, E.D. Carstea, J.Z. Gu, C. Cummings, A. Brown, J. Ellison, K. Ohno, M.A. Rosenfeld, D.A. Tagle, P.G. Pentchev, and W.J. Pavan Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene Science 277 1997 232 235
13. S. Murase, and Y. Hayashi Neuronal expression of macrophage colony stimulating factor in Purkinje cells and olfactory mitral cells of wild-type and cerebellar-mutant mice J. Mol. Histol. 34 2002 85 95
14. S.C. Patel, S. Suresh, U. Kumar, C.Y. Hu, A. Cooney, E.J. Blanchette-Mackie, E.B. Neufeld, R.C. Patel, R.O. Brady, Y.C. Patel, P.G. Pentchev, and W.Y. Ong Localization of Niemann-Pick C1 protein in astrocytes: implications for neuronal degeneration in Niemann-Pick type C disease Proc. Natl. Acad. Sci. U.S.A. 96 1999 1657 1662
15. P.G. Pentchev, M.E. Comly, H.S. Kruth, M.T. Vanier, D.A. Wenger, S. Patel, and R.O. Brady A defect in cholesterol esterification in Niemann-Pick disease (type C) patients Proc. Natl. Acad. Sci. U.S.A. 82 1985 8247 8251
16. R.F. Pereira, M.D. O'Hara, A.V. Laptev, K.W. Halford, M.D. Pollard, R. Class, D. Simon, K. Livezey, and D.J. Prockop Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta Proc. Natl. Acad. Sci. U.S.A. 95 1998 1142 1147
17. D. Prockop Marrow stromal cells as stem cells for nonhematopoietic tissues Science 276 1997 71 74
18. H. Suzuki, H. Franz, T. Yamamoto, Y. Iwasaki, and H. Konno Identification of the normal microglial population in human and rodent nervous tissue using lectin-histochemistry Neuropathol. Appl. Neurobiol. 14 1988 221 227
19. D. Woodbury, E.J. Schwarz, D.J. Prockop, and I.B. Black Adult rat and human bone marrow stromal cells differentiate into neurons J. Neurosci. Res. 61 2000 364 370
20. G. del Zoppo, I. Ginis, J.M. Hallenbeck, C. Iadecola, X. Wang, and G.Z. Feuerstein Inflammation and stroke: putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia Brain Pathol. 10 2000 95 112