Interrelation between long-chain fatty acid oxidation rate and carnitine palmitoyltransferase 1 activity with different isoforms in rat tissues

Life Sciences

Volumn 77, Issue 4, 2005, Pages 435-443

  Doh, Kyung Oh ^a   Kim, Yong Woon ^a   Park, So Young ^a   Lee, Suck Kang ^a   Park, Jae Sik ^b   Kim, Jong Yeon ^a  

^a Yeungnam University College of Medicine   (South Korea)

^b Kyungpook National University   (South Korea)

Author keywords

Carnitine palmitoyltransferase 1; Lipid oxidation; Long chain fatty acid

Indexed keywords

CARNITINE PALMITOYLTRANSFERASE; ISOENZYME; LONG CHAIN FATTY ACID; PALMITIC ACID;

ADIPOSE TISSUE; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; GASTROCNEMIUS MUSCLE; HEART; KIDNEY PARENCHYMA; LIVER; MALE; NONHUMAN; OXIDATION KINETICS; PROTEIN FUNCTION; RAT; STATISTICAL SIGNIFICANCE;

ADIPOSE TISSUE; ANIMALS; CARNITINE O-PALMITOYLTRANSFERASE; ISOENZYMES; KIDNEY; LIVER; MALE; MUSCLE, SKELETAL; MYOCARDIUM; ORGAN SPECIFICITY; OXIDATION-REDUCTION; PALMITATES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 19344362054     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.11.032     Document Type: Article

References (35)

1. J. An, D.M. Muoio, M. Shiota, Y. Fujimoto, G.W. Cline, G.I. Shulman, T.R. Koves, R. Stevens, D. Millington, and C.B. Newgard Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance Nature Medicine 10 2004 268 274
2. N. Alam, and E. Saggerson Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscle Biochemical Journal 334 1998 233 241
3. A. Astrup, A. Raven, B. Bultmann, and S. Toubro Fat metabolism in the predisposition to obesity Annals of the New York Academy of Science 827 1997 417 430
4. J.M. Brandt, F. Djouadi, and D.P. Kelly Fatty acids activate transcription of the muscle carnitine palmitoyl transferase I gene in cardiac myocytes via the peroxisome proliferator-activated receptor alpha Journal of Biological Chemistry 273 1998 23786 23792
5. R. Bressler, R. Gay, J.G. Copeland, J.J. Bahl, J. Bedotto, and S. Goldman Chronic inhibition of fatty acid oxidation: new model of diastolic dysfunction Life Sciences 44 1989 1897 1906
6. N.F. Brown, J.K. Hill, V. Esser, J.L. Kirkland, B.E. Corkey, D.W. Foster, and J.D. McGarry Mouse white adipocytes and 3T3-L1 cells display an anomalous pattern of carnitine palmitoyl transferase (CPT) I isoform expression during differentiation. Inter-tissue and inter-species expression of CPT I and CPT II enzymes Biochemical Journal 327 1997 225 231
7. N.F. Brown, B.C. Weis, J.E. Husti, D.W. Foster, and J.D. McGarry Mitochondrial carnitine palmitoyltransferse 1 isoform switching in the developing rat heart Journal of Biological Chemistry 270 1995 8952 8957
8. S.R. Colberg, J.A. Simoneau, F.L. Thaete, and D.E. Kelley Skeletal muscle utilization of free fatty acids in women with visceral obesity Journal of Clinical Investigation 95 1995 1846 1853
9. R.A. Coleman, T.M. Lewin, C.G. VanHorn, and M.R. Gonzalez-Baro Do long-chain acyl-CoA synthetases regulate fatty acid entry into synthetic versus degradative pathways? Journal of Nutrition 132 2002 2123 2126
10. G.R. Dagenais, R.G. Tancredi, and K.L. Zierler Free fatty acid oxidation by forearm muscle at rest, and evidence for an intramuscular lipid pool in the human forearm Journal of Clinical Investigation 58 1976 421 431
11. S. Eaton, K. Fukumoto, N.P. Duran, A. Pierro, L. Spitz, P.A. Quant, and K. Bartlett Carnitine palmitoyl tansferase 1 and the control of myocardial β-oxidation flux Biochemical Society Transaction 29 2001 245 250
12. B. Essen, E. Jansson, J. Henriksson, A.W. Taylor, and B. Saltin Metabolic characteristics of fiber types in human skeletal muscles Acta Physiologica Scandinavica 95 1975 153 165
13. V. Esser, N.F. Brown, A.T. Cowan, D.W. Foster, and J.D. McGarry Expression of a cDNA isolated from rat brown adipose tissue and heart identifies the product as the muscle isoform of carnitine palmitoyl transferase I (M-CPT I). M-CPT I is the predominant CPT I isoform expressed in both white (epididymal) and brown adipocytes Journal of Biological Chemistry 271 1996 6972 6977
14. V. Esser, C.H. Britton, B.C. Weis, D.W. Foster, and J.D. McGarry Cloning, sequencing, and expression of a cDNA encoding rat liver carnitine palmitoyl transferase I. Direct evidence that a single polypeptide is involved in inhibitor interaction and catalytic function Journal of Biological Chemistry 268 1993 5817 5822
15. W.G. Guder, S. Wagner, and G. Wirthenson Metabolic fuels along the nephron: pathways and intracellular mechanisms of interaction Kidney International 29 1986 41 45
16. D.E. Kelley, B. Goodpaster, R.R. Wing, and J.A. Simoneau Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss American Journal of Physiology 277 1999 E1130 E1141
17. J.Y. Kim, R.C. Hickner, R.L. Cortright, G.L. Dohm, and J.A. Houmard Lipid oxidation is reduced in obese human skeletal muscle American Journal of Physiology 279 2000 E1039 E1044
18. J.Y. Kim, R.C. Hickner, G.L. Dohm, and J.A. Houmard Long-and medium-chain fatty acid oxidation is increased in exercise-trained human skeletal muscle Metabolism 51 2002 460 464
19. J.Y. Kim, T.R. Koves, G.S. Yu, T. Gulick, R.L. Cortright, G.L. Dohm, and D.M. Muoio Evidence of a malonyl-CoA-insensitive carnitine palmitoyl transferase I activity in red skeletal muscle American Journal of Physiology 282 2002 E1014 E1022
20. W.E. Kraus, C.E. Torgan, and D.A. Taylor Skeletal muscle adaptation to chronic low-frequency motor nerve stimulation Exercise and Sport Sciences Reviews 22 1994 313 360
21. G.D. Lopaschuk, D.D. Belke, J. Gamble, T. Itoi, and B.O. Schonekess Regulation of fatty acid oxidation in the mammalian heart in health and disease Biochimica et Biophysica Acta 1213 1994 263 267
22. J.D. McGarry The mitochondrial carnitine palmitoyl transferase system: its broadening role in fuel homoeostasis and new insights into its molecular features Biochemical Society Transaction 23 1995 321 324
23. J.D. McGarry, and N.F. Brown The mitochondrial carnitine palmitoyl transferase system from concept to molecular analysis European Journal of Biochemistry 244 1997 1 14
24. J.D. McGarry, S.E. Mills, C.S. Long, and D.W. Foster Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyl transferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat Biochemical Journal 214 1983 21 28
25. J.D. McGarry, M.J. Stark, and D.W. Foster Hepatic malonyl CoA levels of fed, fasted and diabetic rats as measured using a simple radioisotopic assay Journal of Biological Chemistry 253 1978 8291 8293
26. D.G. Nicholls, and R.M. Locke Thermogenic mechanisms in brown fat Physiological Reviews 64 1984 1 64
27. M.J. Pagliassotti, E.C. Gayles, and J.O. Hill Fat and energy balance Annals of the New York Academy of Science 827 1997 431 448
28. H.R. Scholte, Y. Yu, J.D. Ross, I.I. Oosterkamp, A.M. Boonman, and H.F. Busch Rapid isolation of muscle and heart mitochondria, the ability of oxidative phosphorylation and attempts to stabilize the process in vitro by taurine, carnitine and other compounds Molecular and Cellular Biochemistry 174 1997 61 66
29. P. Schrauwen, K. Walder, and E. Ravussin Human uncoupling proteins and obesity Obesity Research 7 1999 97 105
30. W.C. Stanley, S.R. Meadows, K.M. Kivilo, B.A. Roth, and G.D. Lopaschuk β-hydroxybutyrate inhibits myocardial fatty acid oxidation in vivo independent of changes in malonyl-CoA content American Journal of Physiology 285 2003 H1626 H1631
31. F.R. Van der leji, K.B. Cox, V.N. Jackson, N.C.A. Huijkman, B. Barteld, J.R.G. Kuipers, T. Dijkhuizen, P. Terpstra, P.A. Wood, V.A. Zammit, and N.T. Price Structural and functional genomics of the CPT1B gene for muscle-type carnitine palmitoyl transferase I in mammals Journal of Biological Chemistry 277 2002 26994 27005
32. B.C. Weis, A.T. Cowan, N.F. Brown, D.W. Foster, and J.D. McGarry Use of a selective inhibitor of liver carntine palmitoyl transferase 1 activity allows quantification of its contribution to total CPT1 activity in rat heart Journal of Biological Chemistry 269 1994 26443 26448
33. N. Yamazaki, Y. Shinohara, A. Shima, and H. Terada High expression of a novel carnitine palmitoyl transferase I like protein in rat brown adipose tissue and heart: isolation and characterization of its cDNA clone FEBS Letters 363 1995 41 45
34. V.A. Zammit Carnitine acyltansferases: functional significance of subcellular distribution and membrane topololgy Progress in Lipid Research 38 1999 199 224
35. S. Zierz, and A.G. Engel Different sites of inhibition of carnitine palmitoyl transferase by malonyl-CoA, and by acetyl-CoA and CoA, in human skeletal muscle Biochemical Journal 245 1987 205 209