Site-directed mutations of human hemoglobin at residue 35β: A residue at the intersection of the α1β1, α1β2, and α1β2, interfaces

Protein Science

Volumn 10, Issue 9, 2001, Pages 1847-1855

  Kavanaugh, Jeffrey S ^a   Weydert, Jamie A ^a   Rogers, Paul H ^a   Arnone, Arthur ^a   Hui, Hilda L ^b   Wierzba, Anita M ^b   Kwiatkowski, Laura D ^b   Paily, Paul ^b   Noble, Robert W ^b   Bruno, Stefano ^c   Mozzarelli, Andrea ^c  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c UNIVERSITY OF PARMA   (Italy)

Author keywords

Hemoglobin; Ligand affinity; Ligand binding kinetics; Mutant; Single crystal microspectrophotometry; X ray crystallography

Indexed keywords

CARBON MONOXIDE; HEMOGLOBIN; OXYGEN;

ALLOSTERISM; AMINO ACID ANALYSIS; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DISSOCIATION; LIGAND BINDING; OXYGEN AFFINITY; PHOTOLYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN QUATERNARY STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

AMINO ACID SUBSTITUTION; BINDING SITES; CARBON MONOXIDE; CRYSTALLOGRAPHY, X-RAY; HEMOGLOBINS; HUMANS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; OXYGEN; PHOTOLYSIS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN SUBUNITS; THERMODYNAMICS; TYROSINE;

EID: 19244378820     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.16401     Document Type: Article

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