Renal effects of the cyclooxygenase-inhibiting nitric oxide donator AZD3582 compared with rofecoxib and naproxen during normal and low sodium intake

Clinical Pharmacology and Therapeutics

Volumn 77, Issue 5, 2005, Pages 437-450

  Huledal, Gunilla ^a   Jonzon, Bror ^b   Malmenäs, Maria ^b   Hedman, Ann ^b   Andersson, Lars I ^b   Odlind, Bo ^b   Brater, D Craig ^b  

^a ASTRAZENECA R AND D   (Sweden)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; IOHEXOL; NAPROXEN; NITRIC OXIDE DONOR; NITRONAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; PROSTAGLANDIN SYNTHASE INHIBITOR; ROFECOXIB; DIAGNOSTIC AGENT; LACTONE; NAPHTHALENE DERIVATIVE; POTASSIUM; RENIN; SODIUM; SULFONE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EFFECT; DRUG STRUCTURE; FEMALE; GLOMERULUS FILTRATION RATE; HEADACHE; HUMAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; SODIUM DEPLETION; SODIUM RESTRICTION; SODIUM URINE LEVEL; STATISTICAL SIGNIFICANCE; BLOOD; BLOOD PRESSURE; COMPARATIVE STUDY; DRUG ADMINISTRATION; METABOLISM; URINE;

ADULT; AREA UNDER CURVE; BLOOD PRESSURE; CYCLOOXYGENASE INHIBITORS; DIET, SODIUM-RESTRICTED; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; IOHEXOL; LACTONES; MALE; NAPHTHALENES; NAPROXEN; NITRIC OXIDE DONORS; POTASSIUM; RENIN; SODIUM; SULFONES;

EID: 19144373563     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clpt.2005.01.011     Document Type: Article

References (16)

1. S. Kaojarern, P. Chennavasin, S. Anderson, D.C. Brater Nephron site of effect of nonsteroidal anti-inflammatory drugs on solute excretion in humans Am J Physiol 244 1983 134 139
2. D.C. Brater Effects of nonsteroidal anti-inflammatory drugs on renal function focus on cyclooxygenase-2-selective inhibition Am J Med 107 1999 65S 71S
3. D.C. Brater, C. Harris, J.S. Redfern, B.J. Gertz Renal effects of COX-2 selective inhibitors Am J Nephrol 21 2001 1 15
4. G. Berndt, N. Grosser, J. Hoogstraate, H. Schroder A common pathway of nitric oxide release from AZD3582 and glyceryl trinitrate Eur J Pharm Sci 21 2004 331 335
5. S. Lohmander, D. McKeith, O. Svensson, M. Malmenäs, L. Bolin, A. Kalla A randomised placebo-controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis Ann Rheum Dis 64 2005 449 456
6. S.K. Swan, D.W. Rudy, K.C. Lasseter, C.F. Ryan, K.L. Buechel, L.J. Lambrecht Effect of cyclooxygenase-2 inhibition on renal function in elderly persons receiving low-salt diet Ann Intern Med 133 2000 1 9
7. J.I. Schwartz, K. Vandormael, M.P. Malice, R.N. Kalyani, K.C. Lasseter, G.B. Holmes Comparison of rofecoxib, celecoxib, and naproxen on renal function in elderly subjects receiving a normal-salt diet Clin Pharmacol Ther 72 2002 50 61
8. J. Rossat, M. Maillard, J. Nussberger, H.R. Brunner, M. Burnier Renal effects of selective cyclooxygenase-2 inhibition in normotensive salt-depleted subjects Clin Pharmacol Ther 66 1999 76 84
9. F. Catella-Lawson, B. McAdam, B.W. Morrison, S. Kapoor, D. Kujubu, L. Antes Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids J Pharmacol Exp Ther 289 1999 735 741
10. D.W. Cockcroft, M.H. Gault Prediction of creatinine clearance from serum creatinine Nephron 16 1976 31 41
11. A. Arvidsson, A. Hedman Plasma and renal clearance of iohexol--a study on the reproducibility of a method for the glomerular filtration rate Scand J Clin Lab Invest 50 1990 757 761
12. M.D. Murray, P.K. Black, D.D. Kuzmik, K.M. Haag, A.K. Manatunga, M.A. Mullin Acute and chronic effects of nonsteroidal antiinflammatory drugs on glomerular filtration rate in elderly patients Am J Med Sci 310 1995 188 197
13. M.C. Kammerl, R.M. Nusing, F. Schweda, D. Endemann, M. Stubanus, F. Kees Low sodium and furosemide-induced stimulation of the rennin system in man is mediated by cyclooxygenase 2 Clin Pharmacol Ther 70 2001 468 474
14. K. Dilger, C. Herrlinger, J. Peters, H.W. Seyberth, H. Schweer, U. Klotz Effects of celecoxib and diclofenac on blood pressure, renal function and vasoactive prostanoids in young and elderly subjects J Clin Pharmacol 42 2002 985 994
15. A.F.C. Lee, D.G. Kiely, W.J. Coutie, A.D. Struthers The effect of nitric oxide inhibition on the renin response to furosemide Br J Clin Pharmacol 48 1999 355 360
16. M. Depré, E. Ehrich, A. Van Hecken, I. De Lepeleire, A. Dallob, P. Wong Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans Eur J Clin Pharmacol 56 2000 167 174