Pulmonary infections increase exhaled nitric oxide in lung transplant recipients: A longitudinal study

Clinical Transplantation

Volumn 19, Issue 3, 2005, Pages 377-382

  Antus, Balazs ^a   Csiszer, Eszter ^a   Czebe, Krisztina ^a   Horvath, Ildiko ^a  

^a NATIONAL KORANYI INSTITUTE OF PULMONOLOGY   (Hungary)

Author keywords

Exhaled; Infection; Lung transplantation; Nitric oxide

Indexed keywords

ANTIBIOTIC AGENT; COTRIMOXAZOLE; CYCLOSPORIN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NITRIC OXIDE; PREDNISONE; TACROLIMUS;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; BACTERIUM CULTURE; BRONCHOSCOPY; CLINICAL ARTICLE; CLINICAL EXAMINATION; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; ENTEROCOCCUS; EXHALATION; FEMALE; FOLLOW UP; HAEMOPHILUS INFLUENZAE; HUMAN; HUMAN TISSUE; LONGITUDINAL STUDY; LOWER RESPIRATORY TRACT INFECTION; LUNG BIOPSY; LUNG FUNCTION TEST; LUNG GRAFT REJECTION; LUNG INFECTION; LUNG TRANSPLANTATION; MALE; MEASUREMENT; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RADIODIAGNOSIS; RECIPIENT; SCREENING TEST; SENSITIVITY AND SPECIFICITY; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; SYMPTOMATOLOGY; THORAX RADIOGRAPHY; UPPER RESPIRATORY TRACT INFECTION;

ADULT; BIOLOGICAL MARKERS; BREATH TESTS; FEMALE; HUMANS; LONGITUDINAL STUDIES; LUNG TRANSPLANTATION; MALE; NITRIC OXIDE; PNEUMONIA, BACTERIAL; SENSITIVITY AND SPECIFICITY;

EID: 19044376898     PISSN: 09020063     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-0012.2005.00354.x     Document Type: Article

References (22)

1. Speich R, van der Bij W. Epidemiology and management of infections after lung transplantation. Clin Infect Dis 2001: 33: S58.
2. Chaparro C, Maurer JR, Chamberlain D et al. Causes of death in lung transplant recipients. J Heart Lung Transplant 1994: 13: 758.
3. Gaston B, Drazen JM, Loscalzo J, Stamler JS. The biology of NO in the airways. Am J Respir Crit Care Med 1994: 149: 538.
4. Kharitonov SA, Yates D, Barnes PJ. Increased nitric oxide in exhaled air of normal human subjects with upper respiratory tract infections. Eur Respir J 1995: 8: 295.
5. de Gouw HW, Grunberg K, Schot R, Kroes AC, Dick EC, Sterk PJ. Relationship between exhaled nitric oxide and airway hyperresponsiveness following experimental rhinovirus infection in asthmatic subjects. Eur Respir J 1998: 11: 126.
6. Gabbay E, Walters EH, Orsida B et al. Post-lung transplant bronchiolitis obliterans syndrome (BOS) is characterized by increased exhaled nitric oxide levels and epithelial inducible nitric oxide synthase. Am J Respir Crit Care Med 2000: 162: 2182.
7. Fisher AJ, Gabbay E, Small T, Doig S, Dark JH, Corris PA. Cross sectional study of exhaled nitric oxide levels following lung transplantation. Thorax 1998: 53: 454.
8. Silkoff PE, Caramori M, Tremblay L et al. Exhaled nitric oxide in human lung transplantation. A noninvasive marker of acute rejection. Am J Respir Crit Care Med 1998: 157: 1822.
9. Gabbay E, Haydn Walters E, Orsida B et al. In stable lung transplant recipients, exhaled nitric oxide levels positively correlate with airway neutrophilia and bronchial epithelial iNOS. Am J Respir Crit Care Med 1999: 160: 2093.
10. Yousem SA, Berry GJ, Cagle PT et al. Revision of the 1990 working formulation for the classification of pulmonary allograft rejection: lung rejection study group. J Heart Lung Transplant 1996: 15: 1.
11. American Thoracic Society. Standardization of Spirometry, 1994 Update. Am J Respir Crit Care Med 1995: 152: 1107.
12. Huszar E, Vass G, Vizi E et al. Adenosine in exhaled breath condensate in healthy volunteers and in patients with asthma. Eur Respir J 2002: 20: 1393.
13. Sanders SP, Siekierski ES, Rickards SM, Porter JD, Imani F, Proud D. Rhinovirus infection induces expression of type 2 nitric oxide synthase in human respiratory epithelial cells in vitro and in vivo. J Allergy Clin Immunol 2001: 107: 235.
14. Wheeler MA, Smith SD, Garcia-Cardena G, Nathan CF, Weiss RM, Sessa WC. Bacterial infection induces nitric oxide synthase in human neutrophils. J Clin Invest 1997: 99: 110.
15. Ochoa JB, Udekwu AO, Billiar TR et al. Nitrogen oxide levels in patients after trauma and during sepsis. Ann Surg 1991: 214: 621.
16. Adrie C, Monchi M, Dinh-Xuan AT, Dall'Ava-Santucci J, Dhainaut JF, Pinsky MR. Exhaled and nasal nitric oxide as a marker of pneumonia in ventilated patients. Am J Respir Crit Care Med 2001: 163: 1143.
17. Soccal PM, Jani A, Chang S, Leonard CT, Pavlakis M, Doyle RL. Inducible nitric oxide synthase transcription in human lung transplantation. Transplantation 2000: 70: 384.
18. Croed KD. Evidence of antiviral effect of nitric oxide: inhibition of herpes simplex type I replication. J Clin Invest 1993: 91: 2446.
19. Noda S, Tanaka K, Sawamura S et al. Role of nitric oxide synthase type 2 in acute infection with murine cytomegalovirus. J Immunol 2001: 166: 3533.
20. Akaike T, Noguchi Y, Ijiri S et al. Pathogenesis of virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci USA 1996: 93: 2448.
21. Worrall NK, Boasquevizque CH, Botney MD et al. Inhibition of inducible nitric oxide synthase ameliorates functional and histological changes of acute lung allograft rejection. Transplantation 1997: 63: 1095.
22. McDermott CD, Gavita SM, Shennib H, Giaid A. Immunohistochemical localization of nitric oxide synthase and the oxidant peroxynitrite in lung transplant recipients with obliterative bronchiolitis. Transplantation 1997: 64: 270.