Cognitive effects of antiepileptic drugs;Efectos cognitivos de los fármacos antiepilépticos

Revista de Neurologia

Volumn 36, Issue 3, 2003, Pages 288-292

  Malagon Valdez J ^a  

^a Clin Atencion Neurodesarrollo   (Mexico)

Author keywords

Anti epileptics; Cognition; Conduct; Epilepsy

Indexed keywords

ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE; CARBAMAZEPINE; CLOBAZAM; CLONAZEPAM; ETIRACETAM; GABAPENTIN; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; TIAGABINE; TOPIRAMATE; VALPROIC ACID; VIGABATRIN; ZONISAMIDE;

AGGRESSION; ANTICONVULSANT THERAPY; BEHAVIOR DISORDER; COGNITION; COGNITIVE DEFECT; CONFERENCE PAPER; CONFUSION; DRUG EFFECT; DRUG MECHANISM; EPILEPSY; HUMAN; IRRITABILITY; METHODOLOGY; NEUROPSYCHOLOGICAL TEST; NEUROTOXICITY; SOMNOLENCE; STANDARD;

EID: 18844476238     PISSN: 02100010     EISSN: None     Source Type: Journal    
DOI: 10.33588/rn.3603.2002156     Document Type: Conference Paper

References (36)

1. Kwan P, Brodie MJ. Neuropsychological effects of epilepsy and antiepileptic drugs. Lancet 2001; 357: 216-22.
2. American Academy of Pediatrics. Committee on Drugs. Behavior and cognitive effects of anticonvulsant therapy. Pediatrics 1985; 76: 644-7.
3. Dodrill CB. Problems in the assessment of cognitive effects of antiepileptic drugs. Epilepsia 1992; 33 (Suppl 6): S29-32.
4. Dodrill CB, Wilensky AJ. Psychological abilities before and after five years of stable antiepileptic drug therapy. Epilepsia 1992; 33: 327-34.
5. Gillham RA, Williams N, Wiedmann KD, Butler E, Larkin JG, Brodie MJ. Concentration-effect relationships with carbamazepine and its epoxide on psychomotor and cognitive function in epileptic patients. J Neurol Neurosurg Psychiatry 1988; 51: 929-33.
6. Voorhies TM. Cognitive and behavioral effects of antiepileptic drugs. Semin Neurol 1988; 8: 35-41.
7. Bourgeois BF. Antiepileptic drugs, learning, and behavior in childhood epilepsy. Epilepsia 1998; 39: 913-21.
8. Williams J, Bates S, Griebel ML, Lange B, Mancias P, Pihoker CM, et al. Does short-term antiepileptic drug treatment in children result in cognitive or behavioral changes? Epilepsia 1998; 39: 1064-9.
9. Drane DL, Meador KJ. Epilepsy, anticonvulsant drugs and cognition. Baillieres Clin Neurol 1996; 5: 877-85.
10. Gillham RA, Williams N, Wiedmann KD, Butler E, Larkin JG, Brodie MJ. Concentration effect relationships with carbamazepine and its epoxide on psychomotor and cognitive function in epileptic patients. J Neurol Neurosurg Psychiatry 1988; 51: 929-33.
11. Brodie MJ, McPhail E, Macphee GJA, Larkin JG, Gray JMB. Psychomotor impairment and anticonvulsant therapy in adult epileptic patients. Euro J Clin Pharmacol 1987; 31: 655-60.
12. Deckers CL, Hekster YA, Keyser A, Meinardi H, Ranier WO. Reappraisal of polytherapy in epilepsy: a critical review of drug load and adverse effects. Epilepsia 1977; 38: 570-75.
13. Camfield CS, Chaplin S, Doyle AB, Schipiro CH, Cummings C, Camfield PR. Side effects of phenobarbital in toddlers. J Pediatr 1979; 95: 361-5.
14. Guillham RA, Williams N, Wiedmann KD, Butler E, Larkin JG, Brodie MJ. Cognitive function in adult epileptic patients established on anticonvulsant monotherapy. Epilepsy Res 1990; 7: 219-25.
15. Kalviainen R, Aikia M, Riekkinen PJ. Cognitive adverse effects of antiepileptic drugs: incidence, mechanisms and therapeutic implications. CNS Drugs 1996; 5: 358-68.
16. Larkin JG, Mckee PJW, Brodie MJ. Rapid tolerance to acute psychomotor impairment with carbamazepine in epileptic patients. Br J Clin Pharmacol 1992; 33: 111-4.
17. Guillham RA, Read CL, Mackee PJW, Larkin JG, Brodie MJ. Cognitive function in adult epileptic patients on long-term sodium valproate. J Epilepsy 1991; 4: 205-10.
18. Bensch J, Bennow G, Ferngren H. A double blind study of clonazepam in the treatment of therapy resistant epilepsy. Dev Med Child Neurol 1977; 19: 335-42.
19. Dichter MA, Brodie MJ. New antiepileptic drugs. N Engl J Med 1996; 334: 1583-90.
20. Smith DB, Mattson RH, Cramer JA, Collins JF, Novelly RA, Craft B. Results of a nationwide Veterans Administration Cooperative Study comparing the efficacy and toxicity of carbamazepine, phenobarbital, phenytoin and primidone. Epilepsia 1987; 28 (Suppl): S50-8.
21. Dodrill CB, Troupin AS. Psychotropic effects of carbamazepine in epilepsy: a double-blind comparison with phenytoin. Neurology 1977; 27: 1023-8.
22. Duncan JS, Shorvon SD, Trimble MR. Effects of removal of phenytoin, carbamazepine and valproate on cognitive function. Epilepsia 1990; 31: 584-91.
23. Martin R, Kuzniecky R, Ho S, Hetherington H, Pan J, Sinclair K, et al. Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults. Neurology 1999; 52: 321-27.
24. Smith D, Baker G, Davies G, Dewey M, Chadwick DW. Outcomes of add-on treatment with lamotrigine in partial epilepsy. Epilepsia 1993; 34: 312-22.
25. Guillham R, Kane K, Briant-Comstock L, Brodie MJ. A double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy with health-related quality of life as an outcome measure. Seizure 2000; 9: 375-79.
26. Wilson EA, Brodie MJ. New antiepileptic drugs. In Brodie MJ, Triman DM, eds. Modern management of epilepsy. London: Bailliere Tindall; 1996.
27. Monaco F. Cognitive effects of vigabatrin: a review. Neurology 1996; 47 (Suppl 1): S6-11.
28. Leach JP, Girvan J, Paul A, Brodie MJ. Gabapentin and cognition: a double blind, dose ranging, placebo controlled study in refractory epilepsy. J Neurol Neurosurg Psychiatry 1997; 62: 372-6.
29. Diamond KR, Pande AC, LaMoreaux L, Pierce MW. Effect of gabapentin on mood and well being in patients with epilepsy. Prog Neuropsychopharmacol Biol Psychiatry 1996; 20: 407-17.
30. Gerber PE, Hamiwka L, Connolly MB, Farrell K. Factors associated with behavioral and cognitive abnormalities in children receiving topiramate. Pediatr Neurol 2000; 22: 200-3.
31. Aldenkamp AP, Baker G, Mulder OG, Chadwick D, Cooper P, Doelman J, et al. A multicenter, randomized clinical study to evaluate the effect on cognitive function of topiramate compared with valproate as add-on therapy to carbamazepine in patients with partial-onset seizures. Epilepsia 2000; 41: 1167-78.
32. Sveinbjornsdottir S, Sander JW, Patsalos PN, Upton D, Thompson PJ, Duncan JS. Neuropsychological effects of tiagabine, a potential new antiepileptic drug. Seizure 1994; 3: 29-35.
33. McKee PJ, Blacklaw J, Forrest G, Gillham RA, Walker SM, Connelly D, et al. A double-blind, placebo-controlled interaction study between oxcarbazepine and carbamazepine, sodium valproate and phenytoin in epileptic patients. Br J Clin Pharmacol 1994; 37: 27-32.
34. Berent S, Sackellares JC, Giordani B, Wagner JG, Donofrio PD, Abou-Kalil B. Zonisamide (CI-912) and cognition: a results from preliminary study. Epilepsia 1987; 28: 1-67.
35. Cramer JA, Arrigo C, van Hammée G, Gauer LJ, Cereghino JJ, for the N132 Study Group. Effect of levetiracetam on epilepsy-related quality of life. Epilepsia 2000; 41: 868-74.
36. American Academy of Pediatrics. Committee on Drugs. Behavioral and cognitive effects of anticonvulsant therapy. Pediatrics 1995; 96: 538-40.