The catalytic subunit of protein phosphatase 2A associates with the translation termination factor eRF1

EMBO Journal

Volumn 15, Issue 24, 1996, Pages 7156-7167

  Andjelković, Nataša ^a   Zolnierowicz, Stanislaw ^a,c   Van Hoof, Christine ^b   Goris, Jozef ^b   A hammings, Brian ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

eRF1; Protein phosphatase 2A; Signal transduction; Translational termination

Indexed keywords

PHOSPHOPROTEIN PHOSPHATASE 2A; TRANSLATION TERMINATION FACTOR;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN COS1; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME PURIFICATION; FETUS; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; NONHUMAN; POLYSOME; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RABBIT; RNA TRANSLATION; SKELETAL MUSCLE; TRANSLATION REGULATION;

EID: 0030466725     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb01107.x     Document Type: Article

References (58)

1. Beaudet,A.L. and Caskey,C.T. (1971) Mammalian peptide chain termination. II. Codon specificity and GTPase activity of release factor. Proc. Natl Acad. Sci. USA, 68, 619-624.
2. Breining,P. and Piepersberg,W. (1986) Yeast omnipotent suppressor SUP1 (SUP45): nucleotide sequence of the wild-type and a mutant gene. Nucleic Acids Res., 14, 5098-5107.
3. Coghlan,V.M., Perrino,B.A., Howard,M., Langeberg,L.K., Hicks,J.B., Gallatin,W.M. and Scott,J.D. (1995) Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. Science, 267, 708-777.
4. Dobrowsky,R.T., Kamibayashi,C., Mumby,M.C. and Hannun,Y.A. (1993) Ceramide activates heterotrimeric protein phosphatase 2A. J. Biol. Chem., 268, 15523-15530.
5. Dunphy,W.G. and Kumagai,A. (1991) The cdc25 protein contains an intrinsic phosphatase activity. Cell, 67, 189-196.
6. Ellis,L., Clauser,E., Morgan,D.O., Edery,M., Roth,R.A. and Rulter,W.J. (1986) Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose. Cell, 45, 721-732.
7. Feinberg,A.P. and Vogelstein,B. (1983) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem., 132, 6-13.
8. Fields,S. and Song,O. (1989) A novel genetic system to detect protein-protein interactions. Nature, 340, 345-346.
9. Foulkes,J.G., Ernst,V. and Levin,D.H. (1983) Separation and identification of type 1 and type 2 protein phosphatases from rabbit reticulocyte lysates. J. Biol. Chem., 258, 1439-1443.
10. Frolova,L. et al. (1994) A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor. Nature, 372, 701-703.
11. Grenett,H.E., Bounelis,P. and Fuller,G.M. (1992) Identification of a human cDNA with high homology to yeast omnipotent suppressor 45. Gene, 110, 239-243.
12. Harlow,E. and Lane,D. (1988) Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
13. Healy,A.M., Zolnierowicz,S., Stapleton,A.E., Goebl,M., DePaoli-Roach,A.A. and Pringle,J.R. (1991) CDC55, a Saccharomyces cerevisiae gene involved in cellular morphogenesis: identification, characterization, and homology to the B subunit of mammalian type 2A protein phosphatase. Mol. Cell. Biol., 11, 5767-5780.
14. Hemmings,B.A., Adams-Pearson,C., Maurer,F., Milller,P., Goris,J., Merlevede,W., Hofsteenge,J. and Stone,S.R. (1990) α- and β-forms of the 65 kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure. Biochemistry, 29, 3166-3173.
15. Hendrix,P., Mayer-Jaekel,R.E., Cron,P., Goris,J., Hofsteenge,J., Merlevede,W. and Hemmings,B.A. (1993a) Structure and expression of a 72 kDa regulatory subunit of protein phosphatase 2A. J. Biol. Chem., 268, 15267-15276.
16. Hendrix,P., Turowski,P., Mayer-Jaekel,R.E., Goris,J., Hofsteenge,J., Merlevede,W. and Hemmings,B.A. (1993b) Analysis of subunit isoforms in protein phosphatase 2A holoenzymes from rabbit and Xenopus. J. Biol. Chem., 268, 7330-7337.
17. Hershey,J.W.B. (1989) Protein phosphorylation controls translation rates. J. Biol. Chem., 264, 20823-20826.
18. Hoshino,S.-I., Miyazava,H., Enomoto,T., Hanaoka,F., Kikuchi,Y., Kikuchi,A. and Ui,M. (1989) A human homologue of the yeast GST1 gene codes for a GTP-binding protein and is expressed in a proliferation-dependent manner in mammalian cells. EMBO J., 8, 3807-3814.
19. Hubbard,M. and Cohen,P. (1993) On target with a new mechanism for the regulation of protein phosphorylation. Trends Biochem. Sci., 81, 172-177.
20. Kamibayashi,C. and Mumby,M.C. (1995) Control of protein phosphatase 2A by multiple families of regulatory subunits. Adv. Protein Phosphatases, 9, 195-210.
21. Kemp,B.E., Bylund,D.B., Huang,T.-S. and Krebs,E.G. (1975) Substrate specificity of the cyclic AMP-dependent protein kinase. Proc. Natl Acad. Sci. USA, 72, 3448-3452.
22. Khew-Goodall,Y., Mayer,R.E., Maurer,F., Stone,S.R. and Hemmings,B.A. (1991) Structure and transcriptional regulation of protein phosphatase 2A catalytic subunit genes. Biochemistry, 30, 89-97.
23. Kleinberger,T. and Shenk,T. (1993) Adenovirus E4orf4 protein binds to protein phosphatase 2A. and the complex down regulates E1A-enhanced junB transcription. J. Virol., 67, 7556-7560.
24. Kushnirov,V.V., Ter-Avanesyan,M.D., Telkov,M.V., Surguchov,A.P., Smirnov,V.N. and Inge-Vechtomov,S.G. (1988) Nucleotide sequence of the SUP2 (SUP35) gene of Saccharomyces cerevisiae. Gene, 66, 45-54.
25. 2-ceramide. J. Biol. Chem., 270, 12808-12813.
26. Mayer,R.E., Hendrix,P., Cron,P., Matthies,R., Stone,S.R., Goris,J., Merlevede,W., Hofsteenge,J. and Hemmings,B.A. (1991) Structure of the 55 kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal specific isoform. Biochemistry, 30, 3589-3597.
27. Mayer-Jaekel,R.E. and Hemmings,B.A. (1994) Protein phosphatase 2A - a 'ménage à trois'. Trends Cell Biol., 4, 287-291.
28. cdc2. J. Cell Sci., 107, 2609-2616.
29. Mochly-Rosen,D. (1995) Localization of protein kinases by anchoring proteins: a theme in signal transduction. Science, 268, 247-251.
30. Mumby,M.C. and Walter,G. (1993) Protein serine/threonine phosphatases: structure, regulation and functions in cell growth. Physiol. Rev., 73, 673-699.
31. Nurse,P. and Thuriaux,P. (1984) Temperature sensitive allosuppressor mutants of the fission yeast S.pombe influence cell cycle control over mitosis. Mol. Gen. Genet., 196, 332-338.
32. Paushkin,S.V., Kushnirov,V.V., Smirnov,V.N. and Ter-Avanesyan,M.D. (1996) Propagation of the yeast prion-like [psi +] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor. EMBO J., 15, 3127-3134.
33. Pallas,D.C., Shahrik,L.K., Martin,B.L., Jaspers,S., Miller,T.B., Brautigan,D.L. and Roberts,T.M. (1990) Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell, 60, 167-176.
34. Pearson,W.R. and Lipman,D.J. (1988) Improved tools for biological sequence comparisons. Proc. Natl Acad. Sci. USA, 85, 2444-2448.
35. Quigley,F.R. (1994) The EMBL data bank, Release 37.
36. Ruediger,R., Hentz,M., Fait,J., Mumby,M. and Walter,G. (1994) Molecular model of the A subunit of protein phosphatase 2A: interaction with other subunits and tumor antigens. J. Virol., 68, 123-129.
37. Sambrook,J., Fritsch,E.F. and Maniatis,T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
38. Sarkar,D., Erlichman,J. and Rubin,C.S. (1984) Identification of a calmodulin-binding protein that co-purifies with the regulatory subunit of brain protein kinase II. J. Biol. Chem., 259, 9840-9846.
39. Seed,B. and Aruffo,A. (1987) Molecular cloning of the CD2 antigen. the T-cell erythrocyte receptor, by a rapid immunoselection procedure. Proc Natl Acad. Sci. USA, 84, 3365-3369.
40. Shacter,E. (1984) Organic extraction of Pi with isobutanol/toluene. Anal. Biochem., 138, 416-420.
41. Sontag,E., Fedorov,S., Kamibayashi,C., Robbins,D., Cobb,M. and Mumby,M. (1994) The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the MAP kinase pathway and induces cell proliferation. Cell, 75, 887-897.
42. Spedding,G. (1990) Isolation and analysis of ribosomes from prokaryotes, eukaryotes, and organelles. In Spedding,G. (ed.), Ribosomes and Protein Synthesis. A Practical Approach. IRL Press at Oxford University Press, pp. 1-29.
43. Stansfield,I. and Tuite,M.F. (1994) Polypeptide chain termination in Saccharomyces cerevisiae. Curr. Genet., 25, 385-395.
44. Stansfield,I., Grant,C.M., Akhmaloka, and Tuite,M.F. (1992) Ribosomal association of the yeast SAL4 (SUP45) gene product: implications for its role in translation fidelity and termination. Mol. Microbiol., 6, 3469-3478.
45. Stansfield,I. et al. (1995) The products of the SUP45 (eRF1) and SUP35 genes interact to mediate translation termination in Saccharomyces cerevisiae. EMBO J., 14, 4365-4373.
46. Strubin,M., Newell,J.W. and Matthias,P. (1995) OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell, 80, 497-506.
47. Tassan,J.P., Le Guellec,K., Kress,M., Faure,M., Camonis,J., Jacquet,M. and Philippe,M. (1993) In Xenopus laevis, the product of a developmentally regulated mRNA is structurally and functionally homologous to a Saccharomyces cerevisiae protein involved in translation fidelity. Mol. Cell. Biol., 13, 2815-2821.
48. Tate,W.P. and Caskey,C.T. (1990) Termination of protein synthesis. In Spedding,G. (ed.), Ribosomes and Protein Synthesis. A Practical Approach. IRL Press at Oxford University Press, pp. 81-100.
49. Tehrani,M.A., Mumby,M.C. and Kamibayashi,C. (1996) Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle. J. Biol. Chem., 271, 5164-5170
50. Tuite,M. and Stansfield,I. (1994) Knowing when to stop. Nature, 372, 614-615.
51. 2 from rabbit skeletal muscle. Eur. J. Biochem., 148, 253-263.
52. Turowski,P., Fernandez,A., Favre,B., Lamb,N.J.C. and Hemmings,B.A. (1995) Differential methylation and altered conformation of cytoplasmic and nuclear forms of protein phosphatase 2A during cell cycle progression. J. Cell Biol., 129, 397-410.
53. Vincent,A., Newman,G. and Liebman,S. (1994) The yeast translational allosuppressor, SAL6: a new member of the PP1-like phosphatase family with a long serine-rich N-terminal extension. Genetics, 138, 597-607.
54. Waelkens,E., Goris,J. and Merlevede,W. (1987) Purification and properties of polycation-stimulated phosphorylase phosphatase from rabbit skeletal muscle. J. Biol. Chem., 262, 1049-1059.
55. Wera,S. and Hemmings,B.A. (1995) Serine/threonine protein phosphatases. Biochem. J., 311, 17-29.
56. Zhouravleva,G., Frolova,L., Le Goff,X., Le Guellec,R., Inge-Vechtomov,S., Kisselev,L. and Philippe,M. (1995) Termination of translation in eukaryotes is governed by two interacting polypeptide chain release factors, eRF1 and eRF3. EMBO J., 14, 4065-4072.
57. Zolnierowicz,S., Csortos,C., Bondor,J., Verin,A., Mumby,M.C. and DePaoli-Roach,A.A. (1994) Diversity in the regulatory B-subunits of protein phosphatase 2A: identification of a novel isoform highly expressed in brain. Biochemistry, 33, 11858-11867.
58. 0 defines a novel multimember family of regulatory subunits. Biochem. J., 317, 187-194.