Neonatal treatment of rats with diethylstilboestrol (DES) induces stromal-epithelial abnormalities of the vas deferens and cauda epididymis in adulthood following delayed basal cell development

Reproduction

Volumn 129, Issue 5, 2005, Pages 589-601

  Atanassova, Nina ^a   McKinnell, Chris ^b   Fisher, Jane ^b   Sharpe, Richard M ^b  

^a Institute of Experimental Morphology and Anthropology Bulgarian Academy of Sciences   (Bulgaria)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; DIETHYLSTILBESTROL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; FLUTAMIDE; GONADORELIN ANTAGONIST; TESTOSTERONE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AZOOSPERMIA; BASAL CELL; CELL COUNT; CELL DIFFERENTIATION; CELL INFILTRATION; CELL MATURATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; EPIDIDYMIS TAIL; EPITHELIUM CELL; GONAD DEVELOPMENT; IMMUNOCOMPETENT CELL; MALE; MALE GENITAL TRACT MALFORMATION; NEWBORN; NONHUMAN; OLIGOSPERMIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUBERTY; RAT; STROMA CELL; TESTOSTERONE SYNTHESIS; VAS DEFERENS;

ANDROGEN ANTAGONISTS; ANIMALS; ANIMALS, NEWBORN; DIETHYLSTILBESTROL; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDIDYMIS; EPITHELIAL CELLS; ESTROGENS, NON-STEROIDAL; FLUTAMIDE; GONADOTROPIN-RELEASING HORMONE; MALE; RATS; RATS, WISTAR; SEXUAL MATURATION; SPERMATOGENESIS; STROMAL CELLS; TESTOSTERONE; VAS DEFERENS;

ANIMALIA;

EID: 18844447754     PISSN: 14701626     EISSN: None     Source Type: Journal    
DOI: 10.1530/rep.1.00546     Document Type: Article

References (52)

1. Aboseif S, El-Sakka A, Young P & Cunha GR 1999 Mesenchymal reprogramming of adult human epithelial differentiation. Differentiation 65 113-118.
2. Arai Y, Mori T, Suzuki Y & Bern HA 1983 Long-term effects of perinatal exposure to sex steroids and diethylstilbestrol on the reproductive system of male mammals. International Reviews of Cytology 84 235-268.
3. Atanassova N, McKinnell C, Turner KJ, Walker M, Fisher JS, Morley M, Millar MR & Sharpe RM 2000 Comparative effects of neonatal exposure of male rats to potent and weak (environmental) estrogens on spermatogenesis at puberty and the relationship to adult testis size and fertility: evidence for stimulatory effects of low estrogen levels. Endocrinology 141 3898-3907.
4. Atanassova N, McKinnell C, Walker M, Turner KJ, Fisher JS, Morley M, Millar MR, Groome NP & Sharpe RM 1999 Permanent effects of neonatal estrogen exposure in rats on reproductive hormone levels, Sertoli cell number, and the efficiency of spermatogenesis in adulthood. Endocrinology 140 5364-5373.
5. Atanassova N, McKinnell C, Williams K, Turner KJ, Fisher JS, Saunders PT, Millar MR & Sharpe RM 2001 Age-, cell- and region-specific immunoexpression of estrogen receptor alpha (but not estrogen receptor beta) during postnatal development of the epididymis and vas deferens of the rat and disruption of this pattern by neonatal treatment with diethylstilbestrol. Endocrinology 142 874-886.
6. Bianko JJ, Handelsman DJ, Pedersen JS & Risbridger GP 2002 Direct response of the murine prostate glad and seminal vesicle to estradiol. Endocrinology 143 4922-4933.
7. Chang WY, Birch L, Woodham C, Gold L & Prins GS 1999 a Neonatal estrogen exposure alters the TGFβ signaling system in the developing rat prostate and interrupts TGFβ-mediated differentiation of the epithelium. Endocrinology 140 2801-2813.
8. Chang WY, Wilson MJ, Birch L & Prins GS 1999b Neonatal estrogen stimulates proliferation of periductal fibroblasts and alters the extracellular matrix composition in the rat prostate. Endocrinology 140 405-415.
9. Corker CS & Davidson DW 1981 Radioimmunoassay of testosterone in various biological fluids without chromatography. Journal of Steroid Biochemistry 9 319-323.
10. Couse JF & Korach KS 1999 Estrogen receptor null mice: what have we learnt and where will they lead us? Endocrine Reviews 20 358-417.
11. Couse JF, Dixon D, Yates M, Moore AB, Ma L, Maas R & Korach KS 2001 Estrogen receptor-alpha knockout mice exhibit resistance to the developmental effects of neonatal diethylstilbestrol exposure on the female reproductive tract. Developmental Biology 238 224-238.
12. Cunha GR 2001 Evidence that epithelial and mesenchymal estrogen receptor-α mediates effects of estrogen on prostatic epithelium. Developmental Biology 229 432-442.
13. Cunha GR, Hayward SW, Dahiya R & Foster BA 1996 Smooth muscle-epithelial interactions in normal and neoplastic prostatic development. Acta Anatomica 155 63-72.
14. Cunha GR, Wang YZ, Hayward SW & Risbridger GP 2001 Estrogenic effects on prostatic differentiation and carcinogenesis. Reproduction Fertility and Development 13 285-296.
15. Cunha GR, Hayward SW, Wang YZ & Ricke WA 2003 Role of the stromal microenvironment in carcinogenesis of the prostate. International Journal of Cancer 107 1-10.
16. Daniely Y, Liao G, Dixon D, Linnoila RI, Lori A, Randell SH, Oren M & Jetten AM 2004 Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium. American Journal of Physiology and Cell Physiology 287 C171-C181.
17. De Marzo AM, Marchi VL, Epstein JI & Nelson WG 1999 Proliferative inflammatory atrophy of the prostate: implications for prostatic carcinogenesis. American Journal of Pathology 155 1985-1992.
18. Donjacour AA & Cunha GR 1991 Stromal regulation of epithelial function. Cancer Treatment Research 53 335-364.
19. Gilleran IP, Putz O, Dejong M, Dejong S, Birch L, Pu Y, Huang L & Prins GS 2003 The role of prolactin in the prostatic inflammatory response to neonatal estrogen. Endocrinology 144 2046-2054.
20. Hayashi N, Cunha GR & Parker M 1993 Permissive and instructive induction of adult rodent prostatic epithelium by heterotypic urogenital sinus mesenchyme. Epithelial Cell Biology 2 66-78.
21. Hayashi T, Yoshinaga A, Ohno R, Ishii N, Kamata S & Yamada T 2004 Expression of the p63 and Notch signalling systems in rat testes during postnatal development: comparison with their expression levels in the epididymis and vas deferens. Journal of Andrology 25 692-698.
22. Higgins SJ, Young P & Cunha GR 1989 Induction of functional cyto-differentiation in the epithelium of tissue recombinants. II. Instructive induction of Wolffian duct epithelia by neonatal seminal vesicle mesenchyme. Development 106 235-250.
23. Holschbach C & Cooper TG 2002 A possible extratubular origin of epididymal basal cells in mice. Reproduction 123 517-525.
24. Imperato-McGinley J, Sanchez RS, Spencer JR, Yee B & Vaughan ED 1992 Comparison of the effects of the 5α-reductase inhibitor finasteride and the antiandrogen flutamide on prostate and genital differentiation: dose-response studies. Endocrinology 131 1149-1156.
25. Ince TA, Cviko AP, Quade BJ, Yang A, McKeon FD, Mutter GL & Crum CP 2002 p63 coordinates anogenital modeling and epithelial cell differentiation in the developing female urogenital tract. American Journal of Pathology 161 1111-1117.
26. Kurita T, Mills AA & Cunha GR 2004a Role of p63 in diethylstilbestrol-induced cervicovaginal adenosis. Development 131 1639-1649.
27. Kurita T, Medina RT, Mills AA & Cunha GR 2004b Role of p63 and basal cells in the prostate. Development 131 4955-4964.
28. van Leenders GJ, Gage WR, Hicks JL, van Balken B, Aalders TW, Schalken JA & De Marzo AM 2003 Intermediate cells in human prostate epithelium are enriched in proliferative inflammatory atrophy. American Journal of Pathology 162 1529-1537.
29. McKinnell C, Atanassova N, Williams K, Fisher JS, Walker M, Turner KJ, Saunders PTK & Sharpe RM 2001 Suppression of androgen action and the induction of gross abnormalities of the reproductive tract in male rats treated neonatally with diethylstilbestrol. Journal of Andrology 22 323-338.
30. Norton AJ, Jordan S & Yeomans P 1994 Brief, high-temperature heat denaturation (pressure cooking): a simple and effective method of antigen retrieval for routinely processed tissues. Journal of Pathology 173 371-379.
31. Prins GS 1992 Neonatal estrogen exposure induces lobe-specific alteration in adult rat prostate androgen receptor expression. Endocrinology 130 3703-3714.
32. Prins GS & Birch L 1995 The developmental pattern of androgen receptor expression in rat prostate lobes is altered after neonatal exposure to estrogen. Endocrinology 136 1303-1314.
33. Prins GS & Birch L 1997 Neonatal estrogen exposure upregulates estrogen receptor expression in the developing and adult prostate lobes. Endocrinology 138 1801-1809.
34. Prins GS, Marmer M, Woodham C, Chang WY, Kuiper G, Gustafsson JA & Birch L 1998 Estrogen receptor-β messenger ribonucleic acid ontogeny in the prostate of normal and neonatally estroginized rats. Endocrinology 139 874-883.
35. Prins GS, Birch L, Couse JF, Choi I, Katzenellenbogen B & Korach KS 2001a Estrogen imprinting of the developing prostate gland is mediated through stromal estrogen receptor α: Studies with αERKO and βERKO mice. Cancer Research 61 6089-6097.
36. Prins GS, Birch L, Habermann H, Chang WY, Tebeau C, Putz O & Bieberich C 2001b influence of neonatal estrogen on prostate development. Reproduction Fertility and Development 13 241-252.
37. Putzi MJ & De Marzo AM 2000 Morphologic transition between proliferative inflammatory atrophy and high-grade prostatic intraepithelial neoplasia. Urology 56 828-832.
38. Risbridger GP, Wang H, Young P, Kurita T, Wong YZ, Lubahn D, Gustafsson J & Cunha GR 2001a Evidence that epithelial and mesenchymal estrogen receptor-α mediates effects of estrogen on prostatic epithelium. Developmental Biology 229 432-442.
39. Risbridger GP, Wang H, Frydenberg M & Cunha GR 2001b The metaplastic effects of estrogen on mouse prostate epithelium: proliferation of cells with basal cell phenotype. Endocrinology 142 2443-2450.
40. Risbridger GP, Bianko JJ, Ellem SJ & McPherson SJ 2003 Estrogens and prostate cancer. Endocrine-Related Cancer 10 187-191.
41. Rivas A, Fisher JS, McKinnell C, Atanassova N & Sharpe RM 2002 Induction of reproductive tract developmental abnormalities in the male rat by lowering androgen production or action in combination with a low dose of diethylstilbestrol: evidence for importance of the androgen-estrogen balance. Endocrinology 143 4797-4808.
42. Rivas A, McKinnell C, Fisher JS, Atanassova N, Williams K & Sharpe RM 2003 Neonatal co-administration of testosterone with diethylstilbestrol prevents diethylstilbestrol induction of most reproductive tract abnormalities in male rats. Journal of Andrology 24 557-567.
43. Robaire B & Hermo L 1988 Efferent ducts, epididymis and vas deferens: Structure, functions and their regulation. In The Physiology of Reproduction, vol 1, pp 999-1080. Eds E Knobil & JD Neill. New York: Raven Press.
44. Saunders PTK, Millar MR, Williams K, Macpherson S, Harkiss D, Anderson RA, Orr B, Groome NP, Scobie G & Fraser HM 2000 Differential expression of estrogen receptor-alpha and -beta and androgen receptor in the ovaries of marmoset and human. Biology of Reproduction 63 1098-1105.
45. Seiler P, Cooper TG & Nieschlag E 2000 Sperm number and condition affect the number of basal cells and their expression of macrophage antigen in the murine epididymis. International Journal of Andrology 23 65-76.
46. Seiler P, Cooper TG, Yeung CH & Nieschlag E 1999 Regional variation in macrophage antigen expression by murine epididymal basal cells and their regulation by testicular factors. Journal of Andrology 20 738-746.
47. Stoker T, Robinette CL & Cooper RL 1999 Perinatal exposure to estrogenic compounds and the subsequent effects on the prostate of the adult rat: evaluation of inflammation in the ventral and lateral lobes. Reproductive Toxicology 13 463-472.
48. Toppari J, Larsen JC, Christiansen P, Giwercman A, Grandjean P, Guillette LJ Jr, Jégou B, Jensen TK, Jouannet P. Keiding N, Leffers H, McLachlan JA, Meyer O, Müller J, Rajpert-De Meyts E, Scheike T, Sharpe RM, Sumpter JS & Skakkebaek NE 1996 Male reproductive health and environmental xenoestrogens. Environmental Health Perspectives 104 (Suppl 4) 741-803.
49. Westfal MD & Pietenpol JA 2004 p63: molecular complexity in development and cancer. Carcinogenesis 25 857-864.
50. Williams K, Fisher JS, Turner KJ, McKinnell C, Saunders PTK & Sharpe RM 2001 Relationship between expression of sex steroid receptors and structure of the seminal vesicles after neonatal treatment of rats with potent or weak estrogens, tamoxifen, flutamide or a GnRH antagonist. Environmental Health Perspectives 109 1227-1235.
51. Williams K, Saunders PT, Atanassova N, Fisher JS, Turner KJ, Millar MR, McKinnell C & Sharpe RM 2000 Induction of progesterone receptor immunoexpression in stromal tissue throughout the male reproductive tract after neonatal oestrogen treatment of rats. Molecular and Cellular Endocrinology 164 117-131.
52. Woodham C, Birch L & Prins GS 2003 Neonatal estrogens down regulate prostatic androgen receptor levels through a proteosome-mediated protein degradation pathway. Endocrinology 144 4841-4850.