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Volumn 40, Issue 5, 2005, Pages 494-504
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Synthesis and anticancer activities of amphiphilic 5-fluoro-2′- deoxyuridylic acid prodrugs
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Author keywords
5 Fluoro 2 deoxyuridine derivatives; Amphiphilic heterodinucleoside phosphates; Anticancer prodrugs; Antimetabolites; Liponucleotide
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Indexed keywords
1 O OCTADECYLGLYCERYLYL (3-5') 5 FLUORO 2' DEOXYURIDINE;
3' O ACETYL 5 FLUORO 2' DEOXYURIDINE;
5 FLUORO 2' DEOXYURIDYLYL (3'-5') 5 FLUORO N 4 HEXADECYL 2' DEOXYCYTIDINE;
5 FLUORO N 4 OCTADECYL 2' DEOXYCYTIDYLYL (3'-5') 5 FLUORO 2' DEOXYURIDINE;
5' FLUORO 2' DEOXYURIDINE 5' MONOPHOSPHATE DERIVATIVE;
5' O (4 MONOMETHOXYTRITYL) 5 FLUORO 2' DEOXYURIDINE;
5' O (4 MONOMETHOXYTRITYL) N 4 PALMITOYL 2' DEOXYCYTIDINE 3' HYDROGEN PHOSPHONATE;
ANTINEOPLASTIC AGENT;
FLUOROURACIL DERIVATIVE;
N 4 PALMITOYL 2' DEOXYCYTIDYLYL (3'-5') 3' O ACETYL 5 FLUORO 2' DEOXYURIDINE;
N 4 PALMITOYL 2',3' DIDEOXYCYTIDYLYL (5'-5') 3' O ACETYL 5 FLUORO 2' DEOXYURIDINE;
UNCLASSIFIED DRUG;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
BRAIN CANCER;
BREAST CANCER;
COLON CANCER;
CONTROLLED STUDY;
DERIVATIZATION;
DRUG EFFECT;
DRUG EFFICACY;
DRUG SPECIFICITY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
HUMAN CELL CULTURE;
IN VITRO STUDY;
KIDNEY CANCER;
LEUKEMIA CELL;
LEUKEMIA CELL LINE;
LUNG NON SMALL CELL CANCER;
MELANOMA;
OVARY CANCER;
PROSTATE CANCER;
STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
ANTIMETABOLITES, ANTINEOPLASTIC;
CELL LINE, TUMOR;
DRUG SCREENING ASSAYS, ANTITUMOR;
FLUORODEOXYURIDYLATE;
HUMANS;
MAGNETIC RESONANCE SPECTROSCOPY;
PRODRUGS;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
SURFACE PROPERTIES;
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EID: 18844440985
PISSN: 02235234
EISSN: None
Source Type: Journal
DOI: 10.1016/j.ejmech.2004.12.006 Document Type: Article |
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Times cited : (14)
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References (23)
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