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Volumn 2, Issue 4, 2005, Pages 447-456
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Utilization of a common pathway for the synthesis of high affinity macrocyclic Grb2 SH2 domain-binding peptide mimetics that differ in the configuration at one ring junction
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Author keywords
[No Author keywords available]
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Indexed keywords
(9H FLUOREN 9 YL)METHYL[1 [[[3 AMINO 1 [[[2 [(5 METHYL 1H INDOL 1 YL)METHYL]PENT 4 EN 1 YL]AMINO]CARBONYL] 3 OXOPROPYL]AMINO]CARBONYL]CYCLOHEXYL]CARBAMATE;
2 [(5 METHYL 1H INDOL 1 YL)METHYL]PENT 4 ENENITRILE;
2 [(5 METHYL 1H INDOLYL)METHYL]PENT 4 ENAMINE;
2 [18 (2 AMINO 2 OXOETHYL) 14 [(5 METHYL 1H INDOL 1 YL)METHYL] 8,17,20 TRIOXO 10[4 (PHOSPHONOMETHYL)PHENYL] 7,16,19 TRIAZASPIRO[5.14]ICOS 11 EN 9 YL]ACETIC ACID;
2 [[(AMINOCYCLOHEXYL)CARBONYL]AMINO] N1 [2 [(5 METHYL 1H INDOL 1 YL)METHYL]PENT 4 EN 1 YL]BUTANEDIAMIDE;
ANTINEOPLASTIC AGENT;
GROWTH FACTOR RECEPTOR BOUND PROTEIN 2;
MACROCYCLIC COMPOUND;
TERT BUTYL 3 [[[1 [[[ 3 AMINO 1 [[[ 2 [(5 METHYL 1H INDOL 1 YL)METHYL]PENT 4 EN 1 YL]AMINO]CARBONYL] 3 OXOPROPYL]AMINO]CARBONYL]CYCLOHEXYL]AMINO]CARBONYL] 4 [4 [[DI(TERT BUTOXY)PHOSPHORYL]METHYL]PHENYL]HEX 5 ENOATE;
TERT BUTYL[18 (2 AMINO 2 OXOETHYL) 10 [4 [[DI(TERT BUTOXY)PHOSPHORYL]METHYL]PHENYL] 14 [(5 METHYL 1H INDOL 1 YL)METHYL] 8,17,20 TRIOXO 7,16,19 TRIAZASPIRO[5.14]ICOS 11 EN 9 YL]ACETATE;
TETRAPEPTIDE;
UNCLASSIFIED DRUG;
ARTICLE;
BINDING AFFINITY;
BIOASSAY;
DRUG PROTEIN BINDING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
LIGAND BINDING;
MOLECULAR DYNAMICS;
PROTEIN DOMAIN;
STEREOCHEMISTRY;
STRUCTURE ANALYSIS;
SURFACE PLASMON RESONANCE;
GRB2 ADAPTOR PROTEIN;
MACROCYCLIC COMPOUNDS;
MOLECULAR STRUCTURE;
PEPTIDES;
PROTEIN STRUCTURE, TERTIARY;
SRC HOMOLOGY DOMAINS;
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EID: 18844430300
PISSN: 16121872
EISSN: 16121880
Source Type: Journal
DOI: 10.1002/cbdv.200590024 Document Type: Article |
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Times cited : (6)
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References (14)
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