Synthesis, in vitro binding and biodistribution in B16 melanoma-bearing mice of new iodine-125 spermidine benzamide derivatives

Nuclear Medicine and Biology

Volumn 32, Issue 4, 2005, Pages 377-384

  Moreau, Marie France ^b   Papon, Janine ^b   Labarre, Pierre ^b   Moins, Nicole ^a   Borel, Michèle ^b   Bayle, Martine ^b   Bouchon, Bernadette ^b   Madelmont, Jean Claude ^b  

^a INSERM   (France)

^b NONE

Author keywords

Iodine 125 benzamides; Melanin binding; Melanoma radiotherapy; Radioactivity biodistribution; Spermidine benzamide derivatives

Indexed keywords

BENZAMIDE DERIVATIVE; MELANIN; N (2 DIETHYLAMINOETHYL) 4 IODOBENZAMIDE I 123; N [4 (3 DIETHYLAMINOPROPYL)AMINOBUTYL] 4 IODOBENZAMIDE I 125; N [4 (3 DIPROPYLAMINOPROPYL)AMINOBUTYL] 4 IODOBENZAMIDE I 125; N [4 (BENZYL) 4 (3 DIPROPYLAMINOPROPYL)AMINOBUTYL] 4 IODOBENZAMIDE I 125; N [4 (METHYL) 4 (3 DIPROPYLAMINOPROPYL)AMINOBUTYL] 4 IODOBENZAMIDE I 125; RADIOPHARMACEUTICAL AGENT; SPERMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BINDING; DRUG DISTRIBUTION; DRUG UPTAKE; ISOTOPE LABELING; LIVER; LUNG; MALE; MOUSE; NONHUMAN; RADIOACTIVITY;

ANIMALS; BENZAMIDES; BODY BURDEN; CELL LINE, TUMOR; IODINE RADIOISOTOPES; MALE; MELANINS; MELANOMA; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED C57BL; ORGAN SPECIFICITY; PROTEIN BINDING; RADIATION DOSAGE; RADIOMETRY; RADIOPHARMACEUTICALS; SPERMIDINE; TISSUE DISTRIBUTION; TUMOR MARKERS, BIOLOGICAL;

EID: 18844411148     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2005.02.004     Document Type: Article

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