Growth hormone receptor mRNA expression in non-functioning and somatotroph pituitary adenomas: Implications for growth hormone substitution therapy?

Experimental and Clinical Endocrinology and Diabetes

Volumn 113, Issue 4, 2005, Pages 214-218

  Beuschlein, Felix ^a   Hancke, K ^a   Petrick, M ^a   Gobel H ^a   Honegger, J ^a   Reincke, M ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Growth hormone; Growth hormone receptor; IGF1; IGF1 receptor; Pituitary adenoma

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE RECEPTOR; MESSENGER RNA; SOMATOMEDIN; SOMATOMEDIN RECEPTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GROWTH HORMONE DEFICIENCY; HORMONE SUBSTITUTION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOPHYSIS ADENOMA; MALE; NEUROSURGERY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA EXTRACTION; TRANSSPHENOIDAL SURGERY;

ACROMEGALY; ADENOMA; DNA PRIMERS; GENE EXPRESSION REGULATION, NEOPLASTIC; GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; PITUITARY NEOPLASMS; RECEPTOR, IGF TYPE 1; RECEPTORS, SOMATOTROPIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 18844400563     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-837668     Document Type: Article

References (18)

1. Chan JM et al. Plasma insulin-like growth factor-1 and prostate cancer risk: a prospective study. Science 1998; 279: 563-566
2. Ebersold MJ et al. Long-term results in transsphenoidal removal of nonfunctioning pituitary adenomas. J Neurosurg 1986; 64: 713-719
3. Giustina A, Veldhuis JD. Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human. Endocr Rev 1998; 19: 717-797
4. Hankinson SE et al. Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet 1998; 351: 1393-1396
5. Khandwala HM et al. The effects of insulin-like growth factors on tumorigenesis and neoplastic growth. Endocr Rev 2000; 21: 215-244
6. Kovacs K, Horvath E. Tumors of the pituitary gland. In: Hartmann WH, Sobin LH (eds). Atlas of Tumor Pathology, Second Series, Fascicle 21. Washington, D. C.: Armed Forces Institute of Pathology, 1986
7. Melmed S. Acromegaly and cancer: not a problem? J Clin Endocrinol Metab 2001; 86: 2929-2934
8. Mertani HC et al. Cellular localization of the growth hormone receptor/binding protein in the human anterior pituitary gland. J Clin Endocrinol Metab 1995; 80: 3361-3367
9. Mindermann T, Wilson CB. Age-related and gender-related occurrence of pituitary adenomas. Clin Endocrinol (Oxf) 1994; 41: 359-364
10. Oomizu S et al. Stimulatory effect of insulin-like growth factor I on proliferation of mouse pituitary cells in serum-free culture. J Endocrinol 1998; 157: 53-62
11. Orme SM et al. Mortality and cancer incidence in acromegaly: a retrospective cohort study. United Kingdom Acromegaly Study Group. J Clin Endocrinol Metab 1998; 83: 2730-2734
12. Resnicoff M et al. Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors. Cancer Res 1994; 54: 2218-2222
13. Sassolas G et al. Management of nonfunctioning pituitary adenomas. Acta Endocrinol (Copenh) 1993; 129: 21-26
14. Schwartz J. Intercellular communication in the anterior pituitary. Endocr Rev 2000; 21: 488-513
15. van der Lely AJ et al. Control of tumor size and disease activity during cotreatment with octreotide and the growth hormone receptor antagonist pegvisomant in an acromegalic patient. J Clin Endocrinol Metab 2001; 86: 478-481
16. Yamasaki H et al. Binding and action of insulin-like growth factor I in pituitary tumor cells. Endocrinology 1991; 128: 857-862
17. Yamashita S et al. Insulin-like growth factor 1 regulates growth hormone secretion and messenger ribonucleic acid levels in human pituitary tumor cells. J Clin Endocrinol Metab 1986; 63: 730-735
18. Zhu T et al. Signal transduction via the growth hormone receptor. Cell Signal 2001; 13: 599-616