The delayed dissolution of paracetamol products in the canine fed stomach can be predicted in vitro but it does not affect the onset of plasma levels

International Journal of Pharmaceutics

Volumn 296, Issue 1-2, 2005, Pages 87-93

  Kalantzi, Lida ^a   Polentarutti, Britta ^b   Albery, Tamsin ^b   Laitmer, Dimitris ^a,d   Abrahamsson, Bertil ^b   Dressman, Jennifer ^c   Reppas, Christos ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b ASTRAZENECA R AND D   (Sweden)

^c GOETHE UNIVERSITY   (Germany)

^d FAMAR SA   (Greece)

Author keywords

Absorption; Acetaminophen; Disintegration; Dissolution; Dogs; Paracetamol

Indexed keywords

PARACETAMOL;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORONAVIRUS; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG SOLUBILITY; FEEDING; FOOD; HYDRODYNAMICS; IN VITRO STUDY; IN VIVO STUDY; MALE; MILK; NONHUMAN; PREDICTION; PRIORITY JOURNAL; SIMULATION; STOMACH; TABLET;

ACETAMINOPHEN; ANIMALS; DOGS; FASTING; FOOD-DRUG INTERACTIONS; GASTRIC EMPTYING; GASTROINTESTINAL CONTENTS; MALE; MILK; PREDICTIVE VALUE OF TESTS; SOLUBILITY; TIME FACTORS;

EID: 18844397260     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2005.02.028     Document Type: Article

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