Growth inhibition and apoptosis induction of human melanoma cells by ω-hydroxy fatty acids

Anti-Cancer Drugs

Volumn 16, Issue 5, 2005, Pages 543-549

  Abe, Akihisa ^a   Sugiyama, Kanji ^b  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

^b MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

Author keywords

hydroxy fatty acids; Apoptosis; Caspases; Melanoma

Indexed keywords

ARACHIDIC ACID; CASPASE 3; DICARBOXYLIC ACID; DNA FRAGMENT; EICOSANEDIOIC ACID; FATTY ALCOHOL; HYDROXY FATTY ACID; HYDROXYL GROUP; MYRISTIC ACID; MYRISTOYL ALCOHOL; OMEGA HYDROXY FATTY ACID; OMEGA HYDROXYEICOSANOIC ACID; OMEGA HYDROXYMYRISTIC ACID; OMEGA HYDROXYPALMITIC ACID; OMEGA HYDROXYSTEARIC ACID; PALMITIC ACID; PALMITOYL ALCOHOL; STEARIC ACID; STEAROYL ALCOHOL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOSE TIME EFFECT RELATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION;

APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS; HUMANS; MELANOMA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 18844389570     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-200506000-00010     Document Type: Article

References (39)

1. Grossman D, Altieri C. Drug resistance in melanoma: mechanism, apoptosis, and new potential therapeutic targets. Cancer Metastasis Rev 2001; 20: 3-11.
2. Soengas MS, Lowe SW. Apoptosis and melanoma chemoresistance. Oncogene 2003; 22:3138-3151.
3. Rodriguez-Vincente J, Vincente-Ortega V, Canteras-Jordana M. The effects of different antineoplastic agents and of pretreatment by modulators on three melanoma lines. Cancer 1998; 82:495-502.
4. Rodriguez-Vincente J, Vincente-Ortega V, Canteras-Jordana M. Azelaic acid has sensitizing effect in the chemotherapeutic treatment of several melanoma cell lines. Pigment Cell Res 1996; 9:317-325.
5. Guerry 4th D, Synnest VM, Elder DE, Shults D. Lessons from tumor progression: the invasive radial growth phase of melanoma is common, incapable of metastasis, and indolent. J Invest Dermatol 1993; 100:3423-3453.
6. Pawlik TM, Veron K, Sondak K. Malignant melanoma. Current state of primary and adjuvant treatment. Crit Rev Oncol/Hematol 2003; 45:245-264.
7. Gadjeva V. Structure-based design of nitrosoureas containing tyrosine derivatives as potential antimelanoma agents. Eur J Med Chem 2002; 37:295-300.
8. Pak BJ, Lee J, Thai BL, Fuchs SY, Shaked Y, Ronai Z, et al. Radiation resistance of human melanoma analyzed by retroviral insertional mutagenesis reveals a possible role for dopachrome tautomerase. Oncogene 2004; 23:30-38.
9. Hsu S, Lewis J, Singh B, Schoenlein P, Osaki T, Athar M, et al. Green tea polyphenol targets the mitochondria in tumor cells inducing caspase 3-dependent apoptosis. Anticancer Res 2003; 23:1533-1540.
10. Yokoyama M, Noguchi M, Nakao Y, Peter A, Iwasawa T. Tea polyphenol, (-)-epigallocatechin gallate effects on growth, apoptosis, and teromerase activity in cervical cell lines. Gynecol Oncol 2004; 92:197-204.
11. 1 arrest and apoptosis in human Jurkat T cells by pentagalloylglucose through inhibiting proteasome activity and elevating p27Kip1, p21 Cip1/WAF1, and Bax proteins. J Biol Chem 2004; 279:13496-13505.
12. Shen SC, Chen YC, Hsu FL, Lee WR. Differential apoptosis-inducing effect of quercetin and its glycosides in human promyeloleukemic HL-60 cells by alternative activation of the caspase 3 cascade. J Cell Biochem 2003; 89:1044-1055.
13. Martin E, Rimbach GH, Gibson GR, Rastall RA. Pectin and pectic-oligosaccharides induce apoptosis in in vitro human colonic adenocarcinoma cells. Anticancer Res 2003; 23:341-346.
14. Abe A, Yamada H, Yamane M, Sugawara I. The ω-hydroxy palmitic acid induced apoptosis in human lung carcinoma cell lines H596 and A549. J Biochem Mol Biol Biophys 2002; 6:37-43.
15. Eglinton G, Hunneman H. Gas chromatographic-mass spectrometric studies of long chain hydroxy acids. Phytochemistry 1968; 7: 313-322.
16. Kolattukudy PE, Walton TJ. The biochemistry of plant cuticular lipids. Prog Chem Fat Lipids 1973; 8;121-175.
17. Kolattukudy PE. Polyesters in higher plants. Adv Biochem Eng/Biotechnol 2001; 71:1-49.
18. K of rat kidney cortex microsomes. Further studies on its interaction with fatty acids. Arch Biochem Biophys. 1973; 158:597-604.
19. Ishiyama M, Miyazono Y, Sasamoto K, Ohkura Y, Ueno K. A highly water-soluble disulfonated tetrazolium salt as a chromogenic indicator for NADH as well as cell viability. Talanta 1997; 44:1299-1305.
20. Gurtu V, Kain SR, Zhang G. Fluorometric and colorimetric detection of caspase activity associated with apoptosis. Anal Biochem 1997; 251: 98-102.
21. Datta R, Kojima H, Banach D, Bump NJ, Talanian RV, Alnemri ES, et al. Activation of a CrmA-insensitive, p35-sensitive pathway in ionizing radiation-induced apoptosis. J Biol Chem 1997; 272:1965-1969.
22. Arends MJ, Morris RG, Wyllie AH. Apoptosis: the role of endonuclease. Am J Pathl 1990; 136:593-608.
23. Corcoran GB, Fix L, Jones DP, Moslen MT, Nicotera P, Oberhammer FA, et al. Apoptosis: molecular control point in toxicology. Toxicol Appl Pharmacol 1994; 128:169-181.
24. Thornberry NA, Lazebnik Y. Caspases: enemies within. Science 1998; 281:1312-1316.
25. Markely KS. Monohydroxyalkanoic acids. In: Markley KS (editor): Fatty Acids, 2nd edn. Part I. Malabar, FL: Krieger; 1983, pp. 65-83.
26. Cave Jr WT. Dietary n-3 (ω-3) polyunsaturated fatty acid effects on animal tumorigenesis. FASEB J 1990; 5:2160-2166.
27. Begin ME, Ells G, Horrobin DF. Polyunsaturated fatty acid-induced cytotoxicity against tumor cells and its relationship to lipid peroxidation. J Natl Cancer Inst 1988; 80:188-194.
28. Das UN. Gamma-linoleic acid, arachidonic acid, and eicosapentaenoic acid as potential anticancer drugs. Nutrition 1990; 6:429-434.
29. Begin ME, Ells G, Das UN, Horrobin DF. Differential killing of human carcinoma cells supplemented with n-3 and n-6 polyunsaturated fatty acids. J Natl Cancer Inst 1986; 77:1053-1062.
30. Esterbauer H. Cytotoxicity and genotoxicity of lipid-oxidation products. Am J Clin Nutr 1993; 57:7793-7863.
31. Grune T, Siems WG, Zollner H, Esterbauer H. Metabolism of 4-hydroxynonenal, a cytotoxic lipid peroxidation product, in Ehrlich mouse ascites cells at different proliferation stages. Cancer Res 1994; 54: 5231-5235.
32. Standstrom PA, Tebby PW, Van Cleave S, Buttke TM. Lipid hydroperoxides induce apoptosis in T cells displaying a HIV-associated glutathione peroxide deficiency. J Biol Chem 1994; 269:798-801.
33. Standstrom PA, Pardi D, Tebby PW, Dudek RW, Terrian DM, Folks TM, et al. Lipid hydroperoxide-induced apoptosis: lack of inhibition by Bcl-2 over-expression. FEBS Lett 1995; 365:66-70.
34. Aoshima H, Satoh T, Sakai N, Yamada M, Enokiko Y, Ikeuchi T, et al. Generation of free radicals during lipid hydroperoxide-triggered apoptosis in PC12h cells. Biochim Biophys Acta 1997; 1345:35-42.
35. Ji C, Rouzer CA, Marnett LJ, Pietenpol JA. Induction of cell cycle arrest by the endogenous product of lipid peroxidation, molondialdehyde. Carcinogenesis 1998; 19:1275-1283.
36. Paumen MB, Ishida Y, Muramatsu M, Yamamoto M, Honjo T. Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis. J Biol Chem 1997; 272:3324-3329.
37. Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1998; 391:43-50.
38. Liu X, Zou H, Slayghter C, Wang X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 1997; 89:175-184.
39. Sakahira H, Enari M, Nagata S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 1998; 391: 96-99.