Implications of multimechanism therapy: When to treat?

Neurology

Volumn 64, Issue 10 SUPPL. 2, 2005, Pages

  Burstein, Rami ^a   Jakubowski, Moshe ^b  

^a HARVARD INSTITUTES OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMIGRAINE AGENT; PROSTAGLANDIN SYNTHASE INHIBITOR; SUMATRIPTAN;

ALLODYNIA; BLOOD VESSEL INNERVATION; DRUG EFFECT; DRUG MECHANISM; MIGRAINE; PRIORITY JOURNAL; REVIEW; SENSITIZATION; TREATMENT INDICATION; TRIGEMINAL NERVE;

EID: 18844366603     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.64.10_suppl_2.s16     Document Type: Review

References (36)

1. Ray BS, Wolff HG. Experimental studies on headache. Pain-sensitive structures of the head and their significance in headache. Arch Surg 1940;41:813-856.
2. Penfield W, McNaughton F. Dural headache and innervation of the dura mater. Arch Neurol Psychiatry 1940;44:43-75.
3. Keller JT, Saunders MC, Beduk A, Jollis JG. Innervation of the posterior fossa dura of the cat. Brain Res Bull 1985;14:97-102.
4. Moskowitz MA, Macfarlane R. Neurovascular and molecular mechanisms in migraine headaches. Cerebrovasc Brain Metab Rev 1993;5: 159-177.
5. Andres KH, von During M, Muszynski K, Schmidt RF. Nerve fibers and their terminals of the dura mater encephali of the rat. Anat Embryol (Berl) 1987;175:289-301.
6. Mayberg M, Langer RS, Zervas NT, Moskowitz MA. Perivascular meningeal projections from cat trigeminal ganglia: possible pathway for vascular headaches in man. Science 1981;213:228-230.
7. Uddman R, Edvinsson L, Ekman R, Kingman T, McCulloch J. Innervation of the feline cerebral vasculature by nerve fibers containing calcitonin gene-related peptide: trigeminal origin and co-existence with substance P. Neurosci Lett 1985;62:131-136.
8. Keller JT, Marfurt CP. Peptidergic and serotoninergic innervation of the rat dura mater. J Comp Neurol 1991;309:515-534.
9. Strassman AM, Raymond SA, Burstein R. Sensitization of meningeal sensory neurons and the origin of headaches. Nature 1996;384:560-564.
10. Beck PW, Handwerker HO. Bradykinin and serotonin effects on various types of cutaneous nerve fibers. Pflugers Arch 1974;347:209-222.
11. Davis KD, Meyer RA, Campbell JN. Chemosensitivity and sensitization of nociceptive afferents that innervate the hairy skin of monkey. J Neurophysiol 1993;69:1071-1081.
12. Mizumura K, Sato J, Kumazawa T. Effects of prostaglandins and other putative chemical intermediaries on the activity of canine testicular polymodal receptors studied in vitro. Pflugers Arch 1987;408:565-572.
13. Neugebauer V, Schaible HG, Schmidt RP. Sensitization of articular afferents to mechanical stimuli by bradykinin. Pflugers Arch 1989;415: 330-335.
14. Steen KH, Reeh PW, Anton P, Handwerker HO. Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro. J Neurosci 1992;12:86-95.
15. Armstrong D, Jepson JB, Keele CA, Stewart JW. Pain-producing substances in human inflammatory exudates and plasma. J Physiol (Lond) 1957;135:350-370.
16. Guzman F, Braun C, Lim RKS. Visceral pain and the pseudoaffective response to intra-arterial injection of bradykinin and other algesic agents. Arch Int Pharmacodyn Ther 1962;136:353-384.
17. Hollander W, Michaelson AL, Wilkins RW. Serotonin and antiserotonins. I. Their circulatory respiratory and renal effects in man. Circulation 1957;16:246-255.
18. Sicuteri F. Vasoneuractive substances and their implication in vascular pain. Res Clin Stud Headache 1967;1:6-45.
19. Burstein R, Yamamura H, Malick A, Strassman AM. Chemical stimulation of the intracranial dura induces enhanced responses to facial stimulation in brain stem trigeminal neurons. J Neurophysiol 1998;79: 964-982.
20. Liveing E. On megrim, sick headache. Nijmegen: Arts & Boeve Publishers, 1873.
21. Wolff HG, Tunis MM, Goodell H. Studies on headache; evidence of damage and changes in pain sensitivity in subjects with vascular headaches of the migraine type. Arch Intern Med 1953;92:478-484.
22. Selby G, Lance JW. Observations on 500 cases of migraine and allied vascular headache. J Neurol Neurosurg Psychiatry 1960;23:23-32.
23. Burstein R, Yarnitsky D, Goor-Aryeh I, Ransil BJ, Bajwa ZH. An association between migraine and cutaneous allodynia. Ann Neurol 2000; 47:614-624.
24. Ji RR, Kohno T, Moore KA, Woolf CJ. Central sensitization and LTP: do pain and memory share similar mechanisms? Trends Neurosci 2003;26: 696-705.
25. Burstein R, Jakubowski M. Analgesic triptan action in an animal model of intracranial pain: a race against the development of central sensitization. Ann Neurol 2004;55:27-36.
26. Burstein R, Jakubowski M, Collins B. Defeating migraine pain with triptans: a race against the development of cutaneous allodynia. Ann Neurol 2004;55:19-26.
27. Potrebic S, Ahn AH, Skinner K, Fields HL, Basbaum AI. Peptidergic nociceptors of both trigeminal and dorsal root ganglia express serotonin 1D receptors: implications for the selective antimigraine action of triptans. J Neurosci 2003;23:10988-10997.
28. Levy D, Jakubowski M, Burstein R. Disruption of communication between peripheral and central trigeminovascular neurons by a 5HT 1B/1D receptor agonist: implications for migraine therapy with triptans. Proc Natl Acad Sci USA 2004;101:6710-6715.
29. Ji RR, Woolf CJ. Neuronal plasticity and signal transduction in nociceptive neurons: implications for the initiation and maintenance of pathological pain. Neurobiol Dis 2001;8:1-10.
30. Ji RR, Rupp F. Phosphorylation of transcription factor CREB in rat spinal cord after formalin-induced hyperalgesia: relationship to c-fos induction. J Neurosci 1997;17:1776-1785.
31. Samad TA, Moore KA, Sapirstein A, et al. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 2001;410:471-475.
32. Hunt SP, Pini A, Evan G. Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature 1987;328:632-634.
33. Ji RR, Befort K, Brenner GJ, Woolf CJ. ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity. J Neurosci 2002;22:478-485.
34. Iadarola MJ, Douglass J, Civelli O, Naranjo JR. Differential activation of spinal cord dynorphin and enkephalin neurons during hyperalgesia: evidence using cDNA hybridization. Brain Res 1988;455:205-212.
35. Mannion RJ, Costigan M, Decosterd I, et al. Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity. Proc Natl Acad Sci USA 1999;96:9385-9390.
36. McCarson KE, Krause JE. NK-1 and NK-3 type tachykinin receptor mRNA expression in the rat spinal cord dorsal horn is increased during adjuvant or formalin-induced nociception. J Neurosci 1994;14:712-720.