Serum levels of macrophage-derived protein MRP-8/14 are elevated in active multiple sclerosis

Neuroscience Letters

Volumn 247, Issue 2-3, 1998, Pages 195-197

  Bogumil, T ^a   Rieckmann, P ^b   Kubuschok, B ^a,c   Felgenhauer, K ^a   Bruck W ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

Immunology; Inflammation; Macrophages; MRP 8; MRP 8 14; Multiple Sclerosis

Indexed keywords

CALGRANULIN;

ADULT; ARTICLE; CLINICAL ARTICLE; DEMYELINATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MACROPHAGE ACTIVATION; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION;

ACUTE DISEASE; ANTIGENS, DIFFERENTIATION; AUTOIMMUNE DISEASES; BIOLOGICAL MARKERS; CALCIUM-BINDING PROTEINS; CALGRANULIN A; CHRONIC DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LEUKOCYTE L1 ANTIGEN COMPLEX; MACROPHAGE ACTIVATION; MEMBRANE GLYCOPROTEINS; MULTIPLE SCLEROSIS; NEURAL CELL ADHESION MOLECULES; RECURRENCE;

EID: 18744433945     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00263-8     Document Type: Article

References (20)

1. Adachi N. Beta-2-microglobulin levels in the cerebrospinal fluid: their value as a disease marker. A review of the recent literature. Eur. Neurol. 31:1991;181-185.
2. 2-microglobulin is related to neurologic impairment in multiple sclerosis. Acta Neurol. Scand. 78:1988;72-75.
3. Burmeister G., Gallacchi G. A selective method for determining MRP8 and MRP14 homocomplexes by sandwich ELISA for the discrimination of active and non-active osteoarthritis from rheumatoid arthritis in sera and synovial fluids. Inflammopharmacol. 3:1995;221-230.
4. Brück W., Porada Ph., Poser S., Rieckmann P., Hanefeld F., Kretzschmar H.A., Lassmann H. Monocyte/macrophage differentiation in early multiple sclerosis lesions. Ann. Neurol. 38:1995;788-798.
5. Dijkstra C.D., de Groot C.J.A., Huitinga I. The role of macrophages in demyelination. J. Neuroimmunol. 40:1992;183-188.
6. Drulovic J., Mostarica-Stojkovic M., Levic Z., Stojsavljevic N., Pravica V., Mesaroš Š. Interleukin-12 and tumor necrosis factor-α levels in cerebrospinal fluid of multiple sclerosis patients. J. Neurol. Sci. 147:1997;145-150.
7. Giovannoni G., Lai M., Kidd D., Thorpe W., Miller D.H., Thompson A.J., Keir G., Feldmann M., Thompson E.J. Daily urinary neopterin excretion as an immunological marker of disease activity in multiple sclerosis. Brain. 120:1997;1-13.
8. 2+-binding proteins of neutrophils and monocytes. J. Leukoc. Biol. 53:1993;197-204.
9. Lackmann M., Cornish C.J., Simpson R.J., Moritz R.L., Geczy C.L. Purification and structural analysis of a murine chemotactic cytokine (CP-10) with sequence homology to S100 proteins. J. Biol. Chem. 267:1992;7499-7504.
10. Lucchinetti C.F., Brück W., Rodriguez M., Lassmann H. Distinct patterns of multiple sclerosis pathology indicates heterogeneity in pathogenesis. Brain Pathol. 6:1996;259-274.
11. Lügering N., Stoll R., Kucharzik T., Schmid K.W., Rohlmann G., Burmeister G., Sorg C., Domschke W. Immunohistochemical distribution and serum levels of the Ca2+-binding proteins MRP8, MRP14 and their heterodimeric form MRP8/14 in Crohn's disease. Digestion. 56:1995;406-414.
12. Mahnke K., Bhardwaj R., Sorg C. Heterodimers of the calcium-binding proteins MRP8 and MRP14 are expressed on the surface of human monocytes upon adherence to fibronectin and collagen. Relation to TNF-alpha, IL-6, and superoxide production. J. Leukoc. Biol. 57:1995;63-71.
13. Martino G., Consiglio A., Franciotta D.M., Corti A., Filippi M., Vandenbroeck K., Sciacca F.L., Comi G., Grimaldi L.M.E. Tumor necrosis factor (and its receptors in relapsing-remitting multiple sclerosis. J. Neurol. Sci. 152:1997;51-61.
14. Nicoletti F., Patti F., Cocuzza C., Zaccone P., Nicoletti A., Di Marco R., Reggio A. Elevated serum levels of interleukin-12 in chronic progressive multiple sclerosis. J. Neuroimmunol. 70:1996;87-90.
15. Poser C.M., Paty D.W., Scheinberg L., McDonald I., Davis F.A., Ebers G.C., Johnson K.P., Sibley W.A., Silberberg D.H., Tourtellotte W.W. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann. Neurol. 13:1983;227-231.
16. Rammes A., Roth J., Goebeler M., Klempt M., Hartmann M., Sorg C. Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathway. J. Biol. Chem. 272:1997;9496-9502.
17. Rentzos M., Nikolaou C., Rombos A., Voumvourakis K., Segditsa I., Papageorgiou C. Tumor necrosis factor alpha is elevated in serum and cerebrospinal fluid in multiple sclerosis and inflammatory neuropathies. J. Neurol. 243:1996;165-170.
18. Shaw C.E., Dunbar P.R., Macaulay H.A., Neale T.J. Measurement of immune markers in the serum and cerebrospinal fluid of multiple sclerosis patients during clinical remission. J. Neurol. 242:1995;53-58.
19. Spuler S., Yousry T., Scheller A., Voltz R., Holler E., Hartmann M., Wick M., Hohlfeld R. Multiple sclerosis: prospective analysis of TNF-alpha and 55 kDa TNF receptor in CSF and serum in correlation with clinical and MRI activity. J. Neuroimmunol. 66:1996;57-64.
20. Sriram S., Rodriguez M. Indictment of the microglia as the villain in multiple sclerosis. Neurology. 48:1997;464-470.