Sequential finite element model of tissue electropermeabilization

IEEE Transactions on Biomedical Engineering

Volumn 52, Issue 5, 2005, Pages 816-827

  Šel, Davorka ^a   Cukjati, David ^a   Batiuskaite, Danute ^b   Slivnik, Tomaž ^a   Mir, Lluis M ^c,d,e   Miklavčič, Damijan ^a,f  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b VYTAUTAS MAGNUS UNIVERSITY   (Lithuania)

^c INSTITUT GUSTAVE ROUSSY   (France)

^d ECOLE NORMALE SUPÉRIEURE   (France)

^e CNRS   (France)

^f Faculty of Electrical Engineering   (Slovenia)

Author keywords

Electro gene transfer; Electrochemotherapy; Electropermeabilization; Modeling; Validation

Indexed keywords

BIOLOGICAL CELLS; ELECTROPERMEABILIZATION; SPECIFIC CONDUCTIVITY; TISSUE PERMEABILIZATION;

CELLS; COMPUTATIONAL METHODS; ELECTRIC CONDUCTIVITY; ELECTRIC FIELD EFFECTS; ELECTRODES; FINITE ELEMENT METHOD; MAGNETIC PERMEABILITY; MEMBRANES;

TISSUE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRIC CONDUCTIVITY; ELECTRIC FIELD; ELECTRIC POTENTIAL; ELECTROCHEMOTHERAPY; ELECTRODE; ELECTROPORATION; FINITE ELEMENT ANALYSIS; GENE TRANSFER; LIVER; MEASUREMENT; MEMBRANE PERMEABILITY; MODEL; NONHUMAN; RABBIT; TISSUE; TISSUE NECROSIS; VALIDATION PROCESS;

ANIMALS; CELL MEMBRANE PERMEABILITY; COMPUTER SIMULATION; ELECTRIC CONDUCTIVITY; ELECTRIC STIMULATION; ELECTROMAGNETIC FIELDS; ELECTROPORATION; FINITE ELEMENT ANALYSIS; LIVER; MODELS, BIOLOGICAL; RABBITS;

EID: 18744415712     PISSN: 00189294     EISSN: None     Source Type: Journal    
DOI: 10.1109/TBME.2005.845212     Document Type: Article

References (46)

1. E. Neumann, S. Kakorin, and K. Toensing, "Fundamentals of electroporative delivery of drugs and genes," Biochim. Biophys. Acta, vol. 48, pp. 3-16, 1999.
2. J. C. Weaver and Y. A. Chizmadzhev, "Theory of electroporation: a review," Bioelectrochem. Bioenerg., vol. 41, pp. 135-160, 1996.
3. R. Heller, M. Jaroszeski, J. Leo-Messina, R. Perrot, N. Van Voorhis, D. Reintgen, and R. Gilbert, "Treatment of B16 mouse melanoma with the combination of electropermeabilization and chemotherapy," Bioelectrochem. Bioenerg., vol. 36, pp. 83-87, 1995.
4. L. M. Mir, S. Orlowski, J. Belehradek Jr., J. Teissies, M. P. Rols, G. Serša, D. Miklavčič, R. Gilbert, and R. Heller, "Biomedical applications of electric pulses with special emphasis on antitumor electrochemotherapy," Bioelectrochem. Bioenerg., vol. 38, pp. 203-207, 1995.
5. M. Jaroszeski, R. Gilbert, and R. Heller, "Electrochemotherapy: an emerging drug delivery method for the treatment of cancer," Adv. Drug Delivery Rev., vol. 26, pp. 185-197, 1997.
6. L. M. Mir, "Therapeutic perspectives of in vivo cell electropermeabilization," Bioelechem., vol. 53, pp. 1-10, 2000.
7. M. Čemažar, C. S. Parkins, D. J. Chaplin, G. M. Tozre, and G. Serša, "Electroporation of human microvascular endothelial cells: evidence for an anti vascular mechanism of electrochemotherapy," Br. J. Cancer, vol. 84, pp. 565-570, 2001.
8. L. M. Mir, M. F. Bureau, J. Gehl, R. Rangara, D. Rouy, J. M. Caillaud, P. Delaere, D. Branellec, B. Schwartz, and D. Scherman, "High-efficiency gene transfer into skeletal muscle mediated by electric pulses," Proc. Nat. Acad. Sci., vol. 96, pp. 4262-4267, 1999.
9. M. P. Rols, C. Delteil, M. Golzio, P. Dumond, S. Cros, and J. Teissie, "In vivo electrically mediated protein and gene transfer in murine melanoma," Nat. Biotechnol., vol. 16, pp. 168-171, 1998.
10. H. Aihara and J. Miyazaki, "Gene transfer into muscle by electroporation in vivo," Nat. Biotechno., vol. 16, pp. 867-870, 1998.
11. S. Satkauskas, M. F. Bureau, M. Puc, A. Mahfoudi, D. Scherman, D. Miklavčič, and L. M. Mir, "Mechanisms of in vivo DNA electrotransfer: respective contributions for cell electropermeabilization and DNA electrophoresis," Mol. Ther., vol. 5, pp. 1-8, 2002.
12. D. Ferber, "Gene therapy: safer and virus-free?," Science, vol. 294, pp. 1638-1642, 2001.
13. M. Puc, T. Kotnik, L. M. Mir, and D. Miklavčič, "Quantitative model of small molecules uptake after in vitro cell electropermeabilization," Bioelectrochemistry, vol. 60, pp. 1-10, 2003.
14. L. M. Mir and S. Orlowski, "Mechanisms of electrochemotherapy," Adv. Drug Delivery Rev., vol. 35, pp. 107-118, 1999.
15. B. Valič, M. Golzio, M. Pavlin, A. Schatz, C. Faurie, B. Gabriel, J. Teissie, M. P. Rols, and D. Miklavčič, "Effect of electric field induced transmembrane potential on spheroidal cells: theory and experiments," Eur. Biophys. J., vol. 32, pp. 519-528, 2003.
16. M. Pavlin and D. Miklavčič, "Effective conductivity of a suspension of permeabilized cells: a theoretical analysis," Biophys. J., vol. 85, pp. 719-729, 2003.
17. D. Miklavčič, K. Beravs, D. Šemrov, M. Čemažar, F. Demšar, and G. Serša, "The importance of electric field distribution for effective in vivo electroporation of tissues," Biophys. J., vol. 74, pp. 2152-2158, 1998.
18. J. Gehl, T. H. Sorensen, K. Nielsen, P. Raskmark, S. L. Nielsen, T. Skorvsgaard, and L. M. Mir, "In vivo electroporation of skeletal muscle: threshold, efficacy and relation to electric field distribution," Biochim. Biophys. Acta, vol. 1428, pp. 233-240, 1999.
19. K. Brandinsky and I. Daskalov, "Electrical field and current distributions in electrochemotherapy," Bioelectrochem. Bioenerg., vol. 48, pp. 201-208, 1999.
20. R. A. Gilbert, M. J. Jaroszeski, and R. Heller, "Novel electrode designs for electrochemotherapy," Biochim. Biophys. Acta, vol. 1334, pp. 9-14, 1997.
21. M. Puc, S. Čorović, K. Flisar, M. Petkovšek, J. Nastran, and D. Miklavčič, "Techniques of signal generation required for electropermeabilization. Survey of electropermeabilization devices," Bioelechem., vol. 64, pp. 113-124, 2004.
22. D. Miklavčič, D. Šemrov, H. Mekid, and L. M. Mir, "A validated model of in vivo electric field distribution in tissue for electrochemotherapy and for DNA electrotransfer for gene therapy," Biochim. Biophys. Acta, vol. 1523, pp. 73-83, 2000.
23. G. A. Hofmann, S. B. Dev, S. Dimmer, and G. S. Nanda, "Electroporation therapy: a new approach for the treatment of head and neck cancer," IEEE Trans. Biomed. Eng, vol. 46, no. 6, pp. 752-759, Jun. 1999.
24. J. Gehl and L. M. Mir, "Determination of optimal parameters for in vivo gene transfer by electroporation, using a rapid in vivo test for cell permeabilization," Biochem. Biophys. Res. Comm., vol. 261, pp. 377-380, 1999.
25. S. B. Dev, D. Dhar, and W. Krassowska, "Electric field of a six-needle array electrode used in drug and DNA delivery in vivo: analytical versus numerical solution," IEEE Trans. Biomed. Eng., vol. 50, no. 11, pp. 1296-1300, Nov. 2003.
26. I. G. Abidor, A. I. Barbul, D. V. Zhelev, I. N. Bandrina, E. M. Osipova, and S. I. Sukharev, "Electrical properties of cell pellets and cell electrofusion in a centrifuge," Biochim. Biophys. Acta, vol. 1152, pp. 207-218, 1993.
27. M. Hibino, H. Itoh, and K. Kinosita Jr, "Time course of cell electroporation as revealed by submicrosecond imaging of transmembrane potential," Biophys. J., vol. 64, pp. 1789-1800, 1993.
28. R. Davalos, B. Rubinsky, and D. M. Otten, "A feasibility study for electrical impedance tomography as a means to monitor tissue electroporation for molecular medicine," IEEE Trans. Biomed. Eng., vol. 49, no. 4, pp. 400-403, Apr. 2002.
29. I. G. Abidor, L. H. Li, and S. W. Hui, "Studies of cell pellets II. Osmotic properties, electroporation and related phenomena: membrane interactions," Biophys. J., vol. 67, pp. 427-435, 1994.
30. D. Šel, S. Mazeres, J. Teissie, and D. Miklavčič, "Finite element modeling of needle electrodes in tissue from the perspective of frequent model computation," IEEE Trans. Biomed. Eng., vol. 50, no. 11, pp. 1-12, Nov. 2003.
31. T. J. C. Faes, H. A. van der Meij, J. C. de Munck, and R. M. Heethaar, "The electric resistivity of human tissues (100 Hz-10 MHz) a meta-analysis of review studies," Physiol. Meas., vol. 20, pp. R1-R10, 1999.
32. L. A. Geddes and L. E. Baker, "Specific resistance of biological material-a compendium of data for the biomedical engineer and physiologist," Med. Biol. Eng., vol. 5, pp. 271-293, 1967.
33. S. Rush, J. A. Abildskov, and R. McFee, "Resistivity of body tissue at low frequencies," Circ. Res., vol. XII, pp. 40-50, 1963.
34. P. Schwan and C. F. Key, "The conductivity of living tissues," Ann. New York Acad. Sci., vol. 65, pp. 1007-1013, 1957.
35. J. Teissie and M. P. Rols, "An experimental evaluation of the critical potential difference inducing cell membrane electropermeabilization, " Biophys. J., vol. 65, pp. 409-413, 1993.
36. E. Neumann and S. Kakorin, "Electrooptics of membrane electroporation and vesicles shape deformation," Curr. Opin. Colloid Interface Sci., vol. 1, pp. 790-799, 1996.
37. D. J. Murray-Smith, "Advances in simulation model validation: theory, software and applications," in Proc. EUROSIM '95, 1995, pp. 75-84.
38. F. A. Duck, Physical Properties of Tissue: A Comprehensive Reference Book. New York: Academic, 1990.
39. D. C. Chang and T. S. Reese, "Changes in membrane structure induced by electroporation as revealed by rapid freezing electron microscopy," Biophys. J., vol. 58, pp. 1-12, 1990.
40. S. J. Marrink, E. Lindahl, O. Edholm, and A. E. Mark, "Simulation of the spontaneous aggregation of phospolipids into bilayers," J. Am. Chem. Soc., vol. 123, pp. 8638-8639, 2001.
41. H. Wolf, M. P. Rols, E. Boldt, E. Neumann, and J. Teissie, "Control by pulse parameters of electric field-mediated gene transfer in mammalian cells," Biophys. J., vol. 66, pp. 524-531, 1994.
42. J. Teissie, N. Eynard, B. Gabriel, and M. P. Rols, " Electropermeabilization of cell membranes," Adv. Drug Delivery Rev., vol. 35, pp. 3-19, 1999.
43. T. Y. Tsong, "Electroporation of cell membranes," Biophys. J., vol. 60, pp. 297-306, 1991.
44. R. Susil, D. Šemrov, and D. Miklavčič, "Electric field induced transmembrane potential depends on cell density and organization," Electro. Magnetobiol., vol. 17, pp. 391-399, 1998.
45. M. Pavlin, N. Pavšelj, and D. Miklavčič, "Dependence of induced transmembrane potential on cell density, arrangement, and cell position inside a cell system," IEEE Trans. Biomed. Eng., vol. 49, no. 6, pp. 605-612, Jun. 2002.
46. K. Kinosita and T. Y. Tsong, "Formation and reseating of pores of controlled sizes in human erythrocyte membrane," Nature, vol. 268, pp. 438-441, 1977.