Electrochemotherapy: An emerging drug delivery method for the treatment of cancer

Advanced Drug Delivery Reviews

Volumn 26, Issue 2-3, 1997, Pages 185-197

  Jaroszeski, Mark J ^a   Gilbert, Richard ^b   Heller, Richard ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b University of South Florida   (United States)

Author keywords

Bleomycin; Chemotherapy; Clinical trial; Electropermeabilization; Electroporation

Indexed keywords

CELL MEMBRANES; ELECTRIC FIELD EFFECTS; MOLECULES; ONCOLOGY;

ELECTROCHEMOTHERAPY; ELECTROPERMEABILIZATION; ELECTROPORATION;

CONTROLLED DRUG DELIVERY;

ANTIINFECTIVE AGENT; BLEOMYCIN;

CANCER; DRUG DELIVERY SYSTEM; DRUG TRANSPORT; ELECTROCHEMOTHERAPY; ELECTROPORATION; HUMAN; PRIORITY JOURNAL; REVIEW;

EID: 0031558236     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(97)00034-3     Document Type: Review

References (55)

1. H.G.L. Coster, A quantitative analysis of the voltage-current relationships of fixed charge membranes and the associated property of 'punch-through'. Biophys. J. 5 (1965) 669-686.
2. A.J.H. Sale, W.A. Hamilton, Effects of high electric fields on microorganisms I. killing of bacteria and yeasts. Biochim. Biophys. Acta 148 (1967) 781-788.
3. A.J.H. Sale, W.A. Hamilton, Effects of high electric fields on microorganisms. II. Lysis of erythrocytes and protoplasts. Biochim. Biophys. Acta 163 (1968) 37-43.
4. H.A. Pohl, J.S. Crane, Dielectrophoresis of cells. Biophys. J. 11 (1971) 711-727.
5. J.M. Crowley, Electrical breakdown of bimolecular lipid membranes as an electromechanical instability. Biophys. J. 13 (1973) 711-724.
6. U. Zimmermann, G. Pilwat, F. Friemann, Dielectric breakdown of cell membranes. Biophys. J. 14 (1974) 881-899.
7. R. Benz, U. Zimmermann, The resealing process of lipid bilayers after reversible electrical breakdown. Biochim. Biophys. Acta 640 (1981) 169-178.
8. U. Zimmermann, Electric field-mediated fusion and related electrical phenomena. Biochim. Biophys. Acta 694 (1982) 227-277.
9. L.V. Chernomordik, S.I. Sukharev, S.V. Popov, V.F. Pastushenko, A.V. Sokirko, I.F. Abidor, Y.A. Chizmadzhev, The electrical breakdown of cell and lipid membranes: the similarity of phenomenologies. Biochim. Biophys. Acta 902 (1987) 360-373.
10. J. Teissie, M.P. Rols, Time course of electropermeabilization, in: M.J. Allen, S.F. Cleary, A.E. Sowers, D. Shillady (Eds.), Charge and Field Effects in Biosystems, 3. Birkhauser, Boston, 1992, pp. 285-301.
11. S.K.H. Foung, S. Perkins, Electric field-induced cell fusion and human monoclonal antibodies. J. Immunol. Methods 116 (1989) 117-122.
12. M.M.S. Lo, T.Y. Tsong, M.K. Conrad, S.M. Strittmatter, L.D. Hester, S.H. Snyder, Monoclonal antibody production by receptor-mediated electrically induced cell fusion. Nature 310 (1984) 792-794.
13. J. Teissie, V.P. Knutson, T.Y. Tsong, M.D. Lane, Electric pulse-induced fusion of 3T3 cells in monolayer culture. Science 216 (1982) 537-538.
14. M.J. Jaroszeski, R. Gilbert, P.G. Fallon, R. Heller, Mechanically facilitated cell-cell electrofusion. Biophys. J. 67 (1994) 1574-1581.
15. R. Heller, R.J. Grasso, Transfer of human membrane surface components by incorporating human cells into intact animal tissue by cell-tissue electrofusion in vivo. Biochim. Biophys. Acta 1024 (1990) 185-188.
16. R.J. Grasso, R. Heller, J.C. Cooley, E.M. Haller, Electrofusion of individual animal cells directly to intact corneal epithelial tissue. Biochim. Biophys. Acta. 980 (1989) 9-14.
17. Y. Mouneimne, T. Pierre-Francois, R. Barhoumi, C. Nicolau, Electroinsertion of xeno proteins in red blood cell membranes yields a long lived protein carrier in circulation. Biochim. Biophys Acta 1066 (1991) 83-89.
18. Y. Mouneimne, T. Pierre-Francois, R. Barhoumi, C. Nicolau, Electroinsertion of full length recombinant CD4 into red blood cell membrane. Biochim. Biophys Acta 1027 (1990) 53-58.
19. L.V. Chernomordik, A.V. Sokolov, V.G. Budker, Electrostimulated uptake of DNA by liposomes. Biochim. Biophys. Acta 1024 (1990) 179-183.
20. Q. Zheng, D.C. Chang, High-efficiency gene transfection by in situ electroporation of cultured cells. Biochim. Biophys. Acta 1088 (1991) 104-110.
21. R. Heller, M. Jaroszeski, A. Atkin, D. Moradpour, R. Gilbert, J. Wands, C. Nicolau, In vivo gene electroinjection and expression in rat liver. FEBS Lett. 389 (1996) 225-228.
22. M.R. Prausnitz, B.S. Lau, C.D. Milano, S. Conner, R. Langer, J.C. Weaver, A quantitative study of electroporation showing a plateau in net molecular transport. Biophys. J. 65 (1993) 414-422.
23. M. Hibino, M. Shigemori, M. Itoh, K. Hagayama, K. Kinosita, Membrane conductance of an electroporated cell analyzed by submicrosecond imaging of transmembrane potential. Biophys. J. 59 (1991) 209-220.
24. W. Mehrl, U. Zimmermann, R. Hamp, Evidence for asymmetrical uptake of fluorescent dyes through electropermeabilized membranes of avena mesophyll protoplasts. FEBS Lett. 185 (1985) 89-94.
25. M. Okino, H. Mohri, Effects of a high-voltage electrical impulse and an anticancer drug on in vivo growing tumors. Jpn. J. Cancer Res. 78 (1987) 1319-1321.
26. L.M. Mir, M. Belehradek, C. Domenge, S. Orlowski, J. Poddevin Jr., G. Schwab, B. Luboinnski, C. Paoletti, Electrochemotherapy, a novel antitumor treatment: first clinical trial. CR Acad. Sci. Paris 313 (1991) 613-618.
27. M. Okino, K. Esato, The effects of a single high voltage electrical stimulation with an anticancer drug on in vivo growing malignant tumors. Jpn. J. Surg. 20(2) (1990) 197-204.
28. M. Okino, H. Tomie, H. Kanesada, M. Marumoto, N. Morita, K. Esato, H. Suzuki, Induction of tumor specific selective toxicity in electrical impulse chemotherapy-analysis of dose response curve. Oncologia 24 (1991) 71-79.
29. M. Okino, H. Tomie, H. Kanesada, M. Marumoto, N. Morita, K. Esato, H. Suzuki, Optimal electric conditions in electrical impulse chemotherapy. Jpn. J. Cancer Res. 83 (1992) 1095-1101.
30. H. Kanesada, Anticancer effect of high voltage pulses combined with concentration dependent anticancer drugs on lewis lung carcinoma, in vivo. J. Jpn. Soc. Cancer Ther. 25(11) (1990) 2640-2648.
31. L.M. Mir, H. Banoun, C. Paoletti, Introduction of definite amounts of nonpermeant molecules into living cells after electropermeabilization: direct access to the cytosol. Exp. Cell Res. 175 (1988) 15-25.
32. S. Orlowski, J. Belehradek Jr., C. Paoletti, L.M. Mir, Transient electropermeabilization of cells in culture. Biochem. Pharm. 37(24) (1988) 4727-4733.
33. L.M. Mir, S. Orlowski, J. Belehradek Jr., C. Paoletti, Electrochemotherapy potentiation of antitumour effect of bleomycin by local electric pulses. Eur. J. Cancer 27(1) (1991) 68-72.
34. J. Belehradek Jr., S. Orlowski, B. Poddevin, C. Paoletti, L.M. Mir, Electrochemotherapy of spontaneous mammary tumors in mice. Eur. J. Cancer 27(1) (1991) 73-76.
35. G. Sersa, S. Novakovic, D. Miklavcic, Potentiation of bleomycin antitumor effectiveness by electrotherapy. Cancer Lett. 69 (1993) 81-84.
36. G. Sersa, M. Cemazar, D. Miclavcic, L.M. Mir, Electrochemotherapy: variable anti-tumor effect on different tumor models. Bioelectrochem. Bioenerg. 35 (1994) 23-21.
37. G. Sersa, M. Cemazar, D. Miklavcic, Antitumor effectiveness of electrochemotherapy with cis-diamminedichloroplatinum (II) in mice. Cancer Res. 55 (1995) 3450-3455.
38. R. Heller, M. Jaroszeski, J. Leo-Messina, R. Perrott, N. Van Voorhis, D. Reintgen, R. Gilbert, Treatment of B16 melanoma with the combination of electroporation and chemotherapy. Bioelectrochem. Bioenerg. 36 (1995) 83-87.
39. L.G. Salford, B.R.R. Persson, A. Brun, C.P. Ceber, P.Ch. Kongstad, L.M. Mir, A new brain tumour therapy combining bleomycin with in vivo electropermeabilization. Biochem. Biophys. Res. Commun. 194 (1993) 938-943.
40. R. Heller, M. Jaroszeski, R. Perrott, J. Messina, R. Gilbert, Effective treatment of B16 melanoma by direct delivery of bleomycin using electrochemotherapy, Melanoma Res. 7 (1997) 10-18.
41. M. Cemazar, D. Miklavcic, L. Vodovnik, T. Jarm, R. Zvonimir, B. Stabuc, T. Cufer, G. Sersa, Improved therapeutic effect of electrochemotherapy with cisplatin by intratumoral drug administration and changing of electrode orientation for electropermeabilization on EAT tumor model in mice. Radiol. Oncol. 29 (1995) 121-127.
42. M.J. Jaroszeski, R. Gilbert, R. Perrott, R. Heller, Enhanced effects of multiple treatment electrochemotherapy, Melanoma Res. 6 (1996) 427-433.
43. G. Sersa, M. Cemazar, D. Semrov, D. Miklavcic, Changing electrode orientation improves the efficacy of electrochemtherapy of solid tumors in mice. Bioelectrochem. Bioenerg. 39 (1996) 61-66.
44. R.A. Gilbert, M.J. Jaroszeski, R. Heller, Novel electrode designs for electrochemotherapy, Biochim. Biophys. Acta 1334 (1997) 9-14.
45. M. Belehradek, C. Domenge, B. Luboinnski, S. Orlowski, J. Belehradek, L.M. Mir, Electrochemotherapy, a new antitumor treatment. Cancer 72(12) (1993) 3694-3700.
46. C. Domenge, S. Orlowski, B. Luboinski, T. DeBaere, G. Schwaab, J. Belehradek Jr., L.M. Mir, Antitumor electrochemotherapy. Cancer 77(5) (1996) 956-963.
47. R. Heller, Treatment of cutaneous nodules using electrochemotherapy. J. Florida Med. Assoc. 82 (1995) 147-150.
48. R. Heller, M.J. Jaroszeski, L.F. Glass, J.L. Messina, D.P. Rapaport, R.C. DeConti, N.A. Fenske, R.A. Gilbert, L.M. Mir, D.S. Reintgen, Phase I/II trial for the treatment of cutaneous and subcutaneous tumors using electrochemotherapy. Cancer 77(5) (1996) 964-971.
49. L.F. Glass, M.L. Pepine, N.A. Fenske, M.J. Jaroszeski, D.S. Reintgen, R. Heller, Bleomycin-mediated electrochemotherapy of metastatic melanoma, Archiv. Derm. 132 (1996) 1353-1357.
50. L.F. Glass, N.A. Fenske, M.J. Jaroszeski, R. Perott, D.T. Harvey, D.S. Reintgen, R. Heller, Bleomycin-mediated electrochemotherapy of basal cell carcinoma. J. Am. Acad. Dermatol. 34(1) (1996) 82-86.
51. D.S. Reintgen, M.J. Jaroszeski, R. Heller, Electrochemotherapy, a novel approach to cancer. J. Skin Cancer Found. 13 (1996) 17-19.
52. Z. Rudolf, B. Stabuc, M. Cemazar, D. Miklavcic, L. Vodovnik, G. Sersa, Electrochemotherapy with bleomycin. The first clinical experience in malignant melanoma patients. Radiol. Oncol. 29 (1995) 229-235.
53. M.J. Jaroszeski, R. Gilbert, R. Heller, In vivo antitumor effects of electrochemotherapy in a hepatoma model. Biochim. Biophys. Acta 1334 (1997) 15-18.
54. L.M. Mir, S. Orlowski, B. Poddevin, J. Belehradek Jr., Electrochemotherapy tumor treatment is improved by interleukin-2 stimulation of the host's defenses. Eur. Cytokine Netw. 3(3) (1992) 331-334.
55. L.M. Mir, C. Roth, S. Orlowski, F. Quintin-Colonna, D. Fradelizi, J. Belehradek Jr., P. Kourilsky, Systemic antitumor effects of electrochemotherapy combined with histoincom-patible cell secreting interleukin-2. J. Immunother. 17 (1997) 30-38.