Low plasma concentrations of retinol and α-tocopherol in hematopoietic stem cell transplant recipients: The effect of mucositis and the risk of infection

American Journal of Clinical Nutrition

Volumn 76, Issue 6, 2002, Pages 1358-1366

  High, Kevin P ^a   Legault, Claudine ^a   Sinclair, Jane A ^a   Cruz, Julia ^a   Hill, Kevin ^a   Hurd, David D ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Hematopoietic stem cell transplantation; Herpes zoster; Infection; Mucositis; Retinol; Tocopherol

Indexed keywords

ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; BUSULFAN; CARBOPLATIN; CARMUSTINE; CYCLOPHOSPHAMIDE; ETOPOSIDE; RETINOL; THIOTEPA;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HERPES ZOSTER; HIGH RISK POPULATION; HUMAN; IMMUNITY; INFECTION; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; NEUTROPENIA; RISK FACTOR; SURVIVAL RATE; VITAMIN BLOOD LEVEL; VITAMIN DEFICIENCY;

HERPES; HERPES ZOSTER;

EID: 18744404524     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/76.6.1358     Document Type: Article

References (52)

1. Armitage JO. Bone marrow transplantation. N Engl J Med 1994;330:827-38.
2. Meyers JD. Infection in bone marrow transplant recipients. Am J Med 1986;81:27-38.
3. Meyers JD. Infection in recipients of bone marrow transplants. Curr Clin Top Infect Dis 1987;6:261-92.
4. Clemens MR, Ladner C, Ehninger G, et al. Plasma vitamin E and beta-carotene concentrations during radiochemotherapy preceding bone marrow transplantation. Am J Clin Nutr 1990;51:216-9.
5. Dürken M, Agbenu J, Finckh B, et al. Deteriorating free radical-trapping capacity and antioxidant status in plasma during bone marrow transplantation. Bone Marrow Transpl 1995;15:757-62.
6. Jonas CR, Puckett AB, Jones DP, et al. Plasma antioxidant status after high-dose chemotherapy: A randomized trial of parenteral nutrition in bone marrow transplantation patients. Am J Clin Nutr 2000;72:181-9.
7. Clemens MR. Vitamins and therapy of malignancies. Ther Umsch 1994;51:483-8 (in German).
8. Clemens MR, Muller-Ladner CI, Gey KF. Vitamins during high dose chemo- and radiotherapy. Z Ernahrungswiss 1992;31:110-20 (in German).
9. Lum LG. The kinetics of immune reconstitution after human marrow transplantation. Blood 1987;69:369-80.
10. Deeg HJ. Graft-versus-host disease: Host and donor views. Semin Hematol 1993;30:110-7.
11. Sonis ST, Oster G, Fuchs H, et al. Oral mucositis and the clinical and economic outcomes of hematopoietic stem-cell transplantation. J Clin Oncol 2001;19:2201-5.
12. Rosenethal D, Lancillotti F, Darwiche N, Sinha R, DeLuca LM. Regulation of epithelial differentiation by retinoids. In: Blumhoff R, ed. Vitamin A in Health and Disease. New York: Marcel Dekker. 1994:425-50.
13. Semba RD. Vitamin A, immunity, and infection. Clin Infect Dis 1994;19:489-99.
14. Blomhoff HK. Role of retinoids in normal hematopoiesis and the immune system. In: B lumhoff R, ed. Vitamin A in Health and Disease. New York: Marcel Dekker, 1994:451-84.
15. Semba RD. The role of vitamin A and related retinoids in immune function. Nutr Rev 1998;56:S38-48.
16. Eckhoff C, Nau H. Identification and quantitation of all-trans- and 13-cis-retinoic acid and 13-cis-4-oxoretinoic acid in human plasma. J Lipid Res 1990:31:1445-54.
17. Kardinaal AF, van Brants HA, van dB, Van SJ, Hermus RJ. Relations between antioxidant vitamins in adipose tissue, plasma, and diet. Am J Epidemiol 1995;141:440-50.
18. Tangney CC, Shekelle RB, Raynor W, Gale M. Betz EP. Intra- and interindividual variation in measurements of beta-carotene, retinol, and tocopherols in diet and plasma. Am J Clin Nutr 1987;45:764-9.
19. Eilers J, Berger AM, Petersen MC. Development, testing, and application of the oral assessment guide. Oncol Nurs Forum 1988;15:325-30.
20. Kenny SA. Effect of two oral care protocols on the incidence of stomatitis in hematology patients. Cancer Nurs 1990;13:345-53.
21. Armstrong TS. Stomatitis in the bone marrow transplant patient. An overview and proposed oral care protocol. Cancer Nurs 1994;17:403-10.
22. Hughes WT, Pizzo PA, Wade JC, Armstrong D, Webb CD, Yunis E. Evaluation of new anti-infective drugs for the treatment of febrile episodes in neutropenic patients. Clin Infect Dis 1992;15:S206-15.
23. Feldman S. Varicella zoster infections in bone marrow transplants. Recent Results Cancer Res 1993;132:175-84.
24. Rowe JM, Ciobanu N, Ascensao J, et al. Recommended guidelines for the management of autologous and allogeneic bone marrow transplantation. A report from the Eastern Cooperative Oncology Group (ECOG). Ann Intern Med 1994;120:143-58.
25. Offidani M, Corvatta L, Olivieri A, et al. A predictive model of varicella-zoster virus infection after autologous peripheral blood progenitor cell transplantation. Clin Infect Dis 2001;32:1414-22.
26. Barton T, Collis T, Stadtmauer, Schuster MG. Infectious complications the year after autologous bone marrow transplantation or peripheral stem cell transplantation for treatment of breast cancer. Clin Infect Dis 2001;32:391-5.
27. Laird NM, Ware JH. Random effects models for longitudinal data. Biometrics 1982;38:963-74.
28. Blomhoff R. Overview of vitamin A metabolism and function. In: Blumhoff R, ed. Vitamin A in Health and Disease. New York: Marcel Dekker. 1994:1-36.
29. Stephensen CB, Alvarez JO, Kohatsu J, Hardmeier R, Kennedy JIJ, Gammon RB Jr. Vitamin A is excreted in the urine during acute infection. Am J Clin Nutr 1994;60:388-92.
30. Szebeni A, Negyesi G. Vitamin A serum levels in burned patients. Orv Hetil 1979;120:2413-5 (in Hungarian).
31. Chapman KM, Prabhudesai M, Erdman JW Jr. Vitamin A status of alcoholics upon admission and after two weeks of hospitalization. J Am Coll Nutr 1993;12:77-83.
32. Boles JM, Garre MA, Youinou PY, et al. Nutritional status in intensive care patients: Evaluation in 84 unselected patients. Crit Care Med 1983;11:87-90.
33. Cohen BE, Gill G, Cullen PR, Morris PJ. Reversal of postoperative immunosuppression in man by vitamin A. Surg Gynecol Obstet 1979;149:658-62.
34. Stephensen CB, Gildengorin G. Serum retinol, the acute phase response, and the apparent misclassification of vitamin A status in the third National Health and Nutrition Examination Survey. Am J Clin Nutr 2000;72:1170-8.
35. Ross AC. Addressing research questions with national survey data the relation of vitamin A status to infection and inflammation. Am J Clin Nutr 2000;72:1069-70.
36. Butler JC, Havens PL, Sowell AL, et al. Measles severity and serum retinol (vitamin A) concentration among children in the United States. Pediatrics 1993;91:1176-81.
37. Coutsoudis A, Kiepiela P, Coovadia HM, Broughton M. Vitamin A supplementation enhances specific IgG antibody levels and total lymphocyte numbers while improving morbidity in measles. Pediatr Infect Dis J 1992;11:203-9.
38. Hussey GD, Klein M. A randomized, controlled trial of vitamin A in children with severe measles. N Engl J Med 1990;323:160-4.
39. Hussey GD, Klein M. Measles-induced vitamin A deficiency. Ann N Y Acad Sci 1992;669:188-94.
40. Arrieta AC, Zaleska M, Stutman HR, Marks MI. Vitamin A levels in children with measles in Long Beach, California. J Pediatr 1992;121:75-8.
41. Frieden RT, Sowell AL, Henning KJ, Huff DL, Gunn RA. Vitamin A levels and severity of measles: New York City. Am J Dis Child 1992;146:182-6.
42. Rhodes J, Oliver S. Retinoids as regulators of macrophage function. Immunology 1980;40:467-72.
43. Rumore MM. Vitamin A as an immunomodulating agent. Clin Pharm 1993;12:506-14.
44. Hatchigian EA, Santos JI, Broitman SA, Vitale JJ. Vitamin A supplementation improves macrophage function and bacterial clearance during experimental salmonella infection. Proc Soc Exp Biol Med 1989;191:47-54.
45. Hiemenz JW, Greene JN. Special considerations for the patient undergoing allogeneic or autologous bone marrow transplantation. Hematol Oncol Clin North Am 1993;7:961-1002.
46. Rowbottom AW, Riches PG, Downie C, Hobbs JR. Monitoring cytokine production in peripheral blood during acute graft-versus-host disease following allogeneic bone marrow transplantation. Bone Marrow Transpl 1993;12:635-41.
47. Ferrara JL. Cytokines other than growth factors in bone marrow transplantation. Curr Opin Oncol 1994;6:127-34.
48. Campos FA, Flores H, Underwood BA. Effect of an infection on vitamin A status of children as measured by the relative dose response (RDR). Am J Clin Nutr 1987;46:91-4.
49. Neuzil KM, Gruber WC, Chytil F, Stahlman MT, Graham BS. Safety and pharmacokinetics of vitamin A therapy for infants with respiratory syncytial virus infections. Antimicrob Agents Chemother 1995;39:1191-3.
50. Bresee JS, Fischer M, Dowell SF, et al. Vitamin A therapy for children with respiratory syncytial virus infection: A multicenter trial in the United States. Pediatr Infect Dis J 1996;15:777-82.
51. Kawasaki Y, Hosoya M, Katayose M, Suzuki H. The efficacy of oral vitamin A supplementation for measles and respiratory syncytyial virus (RSV) infection. Kansenshogaku Zasshi 1999;73:104-9 (in Japanese).
52. Quinlan KP, Hayani KC. Vitamin A and respiratory syncytial virus infection. Serum levels and supplementation trial. Arch Pediatr Adolesc Med 1996;150:25-30.