메뉴 건너뛰기




Volumn 26, Issue 5, 2005, Pages 581-586

Inhibitory of idoxifene on hepatic fibrosis in rats

Author keywords

Fibrosis; Hepatic stellate cell; Idoxifene; Liver; Oxidative stress

Indexed keywords

BROXURIDINE; COLLAGEN; COPPER ZINC SUPEROXIDE DISMUTASE; DIMETHYLNITROSAMINE; GLUTATHIONE PEROXIDASE; IDOXIFENE; NITRILOTRIACETATE IRON; SELECTIVE ESTROGEN RECEPTOR MODULATOR; ANTIOXIDANT; COLLAGEN TYPE 1; DRUG DERIVATIVE; PYRROLIDINO-4-IODOTAMOXIFEN; SUPEROXIDE DISMUTASE; TAMOXIFEN;

EID: 18744395529     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2005.00082.x     Document Type: Article
Times cited : (10)

References (27)
  • 1
    • 0033053455 scopus 로고    scopus 로고
    • Suppressive effects of estradiol on dimethylnitrosamine-induced fibrosis of the liver in rats
    • Yasuda M, Shimizu I, Shiba M, Ito S. Suppressive effects of estradiol on dimethylnitrosamine-induced fibrosis of the liver in rats. Hepatology 1999; 29: 719-27.
    • (1999) Hepatology , vol.29 , pp. 719-727
    • Yasuda, M.1    Shimizu, I.2    Shiba, M.3    Ito, S.4
  • 2
    • 0032923588 scopus 로고    scopus 로고
    • Effects of Sho-saiko-to, a Japanese herbal madicine, on hepatic fibrosis in rats
    • Shimizu I, Ma YR, Mizobuchi Y, Liu F, Miura T, Nakai Y, et al. Effects of Sho-saiko-to, a Japanese herbal madicine, on hepatic fibrosis in rats. Hepatology 1999; 29: 149-60.
    • (1999) Hepatology , vol.29 , pp. 149-160
    • Shimizu, I.1    Ma, Y.R.2    Mizobuchi, Y.3    Liu, F.4    Miura, T.5    Nakai, Y.6
  • 3
    • 0033179380 scopus 로고    scopus 로고
    • Idoxifene antagonizes estradiol-dependent MCF-7 breast cancer xenograft growth through sustained induction of apoptosis
    • Johnston SR, Boeddinghaus IM, Riddler S, Haynes BP, Hardcastle IR, Rowlands M, et al. Idoxifene antagonizes estradiol-dependent MCF-7 breast cancer xenograft growth through sustained induction of apoptosis. Cancer Res 1999; 59: 3646-51.
    • (1999) Cancer Res , vol.59 , pp. 3646-3651
    • Johnston, S.R.1    Boeddinghaus, I.M.2    Riddler, S.3    Haynes, B.P.4    Hardcastle, I.R.5    Rowlands, M.6
  • 5
    • 0034780364 scopus 로고    scopus 로고
    • Reduction of oxidative stress and ATI receptor expression by the selective oestrogen receptor modulator idoxifene
    • Baumer AT, Wassmann S, Ahlbory K, Strehlow K, Muller C, Sauer H, et al. Reduction of oxidative stress and ATI receptor expression by the selective oestrogen receptor modulator idoxifene. Br J Pharmacol 2001; 134: 579-84.
    • (2001) Br J Pharmacol , vol.134 , pp. 579-584
    • Baumer, A.T.1    Wassmann, S.2    Ahlbory, K.3    Strehlow, K.4    Muller, C.5    Sauer, H.6
  • 6
    • 0034960272 scopus 로고    scopus 로고
    • Effects of idoxifene and estradiol on NF-kappaB activation in cultured rat hepatocytes undergoing oxidative stress
    • Omoya T, Shimizu I, Zhou Y, Okamura Y, Inoue H, Lu G, et al. Effects of idoxifene and estradiol on NF-kappaB activation in cultured rat hepatocytes undergoing oxidative stress. Liver 2001; 21: 183-91.
    • (2001) Liver , vol.21 , pp. 183-191
    • Omoya, T.1    Shimizu, I.2    Zhou, Y.3    Okamura, Y.4    Inoue, H.5    Lu, G.6
  • 7
    • 0033869778 scopus 로고    scopus 로고
    • Pathogenesis of liver fibrosis: Role of oxidative stress
    • Poli G. Pathogenesis of liver fibrosis: role of oxidative stress. Mol Aspects Med 2000; 21: 49-98.
    • (2000) Mol Aspects Med , vol.21 , pp. 49-98
    • Poli, G.1
  • 8
    • 0034723290 scopus 로고    scopus 로고
    • Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
    • Friedman SL. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 2000; 275: 2247-50.
    • (2000) J Biol Chem , vol.275 , pp. 2247-2250
    • Friedman, S.L.1
  • 10
    • 0032146551 scopus 로고    scopus 로고
    • Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
    • Iredale JP, Benyon RC, Pickering J, McCullen M, Northrop M, Pawley S, et al. Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest 1998; 102: 538-49.
    • (1998) J Clin Invest , vol.102 , pp. 538-549
    • Iredale, J.P.1    Benyon, R.C.2    Pickering, J.3    McCullen, M.4    Northrop, M.5    Pawley, S.6
  • 11
    • 0025976222 scopus 로고
    • Hepatocyte growth factor in ascites from patiens with cirrhosis
    • Shimizu I, Ichihara A, Nakamura T. Hepatocyte growth factor in ascites from patiens with cirrhosis. J Biochem 1991; 109: 14-8.
    • (1991) J Biochem , vol.109 , pp. 14-18
    • Shimizu, I.1    Ichihara, A.2    Nakamura, T.3
  • 12
    • 0025290814 scopus 로고
    • Kinetic evaluation of free malondialdehyde and enzyme leakage as indices of iron damage in rat hepatocyte cultures
    • Morel I, Lescoat G, Cillard J, Pasdeloup N, Brissot P, Cillard P. Kinetic evaluation of free malondialdehyde and enzyme leakage as indices of iron damage in rat hepatocyte cultures. Biochem Pharmacol 1990; 39: 1647-55.
    • (1990) Biochem Pharmacol , vol.39 , pp. 1647-1655
    • Morel, I.1    Lescoat, G.2    Cillard, J.3    Pasdeloup, N.4    Brissot, P.5    Cillard, P.6
  • 14
    • 18744396025 scopus 로고    scopus 로고
    • Effects of blocking transforming growth factor signaling on culture-activated rat hepatic stellate cells
    • Zhou YJ, Yin DM, Chen HS, Zhu HX, Wan X. Effects of blocking transforming growth factor signaling on culture-activated rat hepatic stellate cells. Chin J Hepatol 2003; 11: 282-4.
    • (2003) Chin J Hepatol , vol.11 , pp. 282-284
    • Zhou, Y.J.1    Yin, D.M.2    Chen, H.S.3    Zhu, H.X.4    Wan, X.5
  • 15
    • 0028838193 scopus 로고
    • Activation of hepatic stellate cells by TGF α and collagen type I mediated by oxidative stress through c-myb expression
    • Lee KS, Buck M, Houglum K, Chojkier M. Activation of hepatic stellate cells by TGF α and collagen type I mediated by oxidative stress through c-myb expression. J Clin Invest 1995; 96: 2461-6.
    • (1995) J Clin Invest , vol.96 , pp. 2461-2466
    • Lee, K.S.1    Buck, M.2    Houglum, K.3    Chojkier, M.4
  • 17
    • 0033028453 scopus 로고    scopus 로고
    • Leukocytes as modulators of stellate cell activation
    • Maher JJ. Leukocytes as modulators of stellate cell activation. Alcohol Clin Exp Res 1999; 23: 917-21.
    • (1999) Alcohol Clin Exp Res , vol.23 , pp. 917-921
    • Maher, J.J.1
  • 19
    • 0034830886 scopus 로고    scopus 로고
    • Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
    • Wright MC, Issa R, Smart DE, Trim N, Murray GI, Primrose JN, et al. Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats. Gastroenterology 2001; 121: 685-98.
    • (2001) Gastroenterology , vol.121 , pp. 685-698
    • Wright, M.C.1    Issa, R.2    Smart, D.E.3    Trim, N.4    Murray, G.I.5    Primrose, J.N.6
  • 20
    • 0036775096 scopus 로고    scopus 로고
    • Induction and regulation of hepatocyte apoptosis by oxidative stress
    • Czaja MJ. Induction and regulation of hepatocyte apoptosis by oxidative stress. Antioxid Redox Signal 2002; 4: 759-67.
    • (2002) Antioxid Redox Signal , vol.4 , pp. 759-767
    • Czaja, M.J.1
  • 22
    • 0036788277 scopus 로고    scopus 로고
    • Fas enhances fibrogenesis in the bile duct ligated mouse: A link between apoptosis and fibrosis
    • Canbay A, Higuchi H, Bronk SF, Taniai M, Sebo TJ, et al. Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis. Gastroenterology 2002; 123: 1323-30.
    • (2002) Gastroenterology , vol.123 , pp. 1323-1330
    • Canbay, A.1    Higuchi, H.2    Bronk, S.F.3    Taniai, M.4    Sebo, T.J.5
  • 23
    • 0035966059 scopus 로고    scopus 로고
    • Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway
    • Faouzi S, Burckhardt BE, Hanson JC, Campe CB, Schrum LW, Rippe RA, et al. Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kappa B-independent, caspase-3-dependent pathway. J Biol Chem 2001; 276: 49077-82.
    • (2001) J Biol Chem , vol.276 , pp. 49077-49082
    • Faouzi, S.1    Burckhardt, B.E.2    Hanson, J.C.3    Campe, C.B.4    Schrum, L.W.5    Rippe, R.A.6
  • 24
    • 18744362680 scopus 로고    scopus 로고
    • Antiapoptotic mechanisms of idoxifene on cultured rat hepatocytes undergoing oxidative stress
    • Zhou YJ, Chen HS, Sha BX. Antiapoptotic mechanisms of idoxifene on cultured rat hepatocytes undergoing oxidative stress. Chin Pharm J 2005; 40: 278-81.
    • (2005) Chin Pharm J , vol.40 , pp. 278-281
    • Zhou, Y.J.1    Chen, H.S.2    Sha, B.X.3
  • 26
    • 0033818343 scopus 로고    scopus 로고
    • Selective oestrogen receptor modulators
    • Burger HG. Selective oestrogen receptor modulators. Horm Res 2000; 53 Suppl 3: 25-9.
    • (2000) Horm Res , vol.53 , Issue.SUPPL. , pp. 25-29
    • Burger, H.G.1
  • 27
    • 1442351143 scopus 로고    scopus 로고
    • Coregulator function: A key to understanding tissue specificity of selective receptor modulators
    • Smith CL, O'Malley BW. Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev 2004; 25: 45-71.
    • (2004) Endocr Rev , vol.25 , pp. 45-71
    • Smith, C.L.1    O'Malley, B.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.