Microbial growth tests in anti-neoplastic injectable solutions

Journal of Oncology Pharmacy Practice

Volumn 11, Issue 1, 2005, Pages 7-12

  Paris, Isabelle ^a   Paci, Angelo ^a   Rey, Jean Baptiste ^a   Bourget, Philippe ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; CYTARABINE; ETOPOSIDE; FLUOROURACIL; IFOSFAMIDE;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL GROWTH; BACTERIUM CONTAMINATION; CANDIDA ALBICANS; CONTROLLED STUDY; CULTURE MEDIUM; DRUG CONTAMINATION; DRUG INDUSTRY; DRUG MANUFACTURE; DRUG QUALITY; DRUG STERILITY; DRUG SYNTHESIS; FUNGAL CONTAMINATION; FUNGUS GROWTH; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; HOSPITAL EQUIPMENT; INCUBATION TIME; INSTRUMENT STERILIZATION; MICROBIOLOGICAL EXAMINATION; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL;

ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BACILLUS SUBTILIS; BACTERIA; CANDIDA ALBICANS; CISPLATIN; CYTARABINE; DRUG COMPOUNDING; DRUG CONTAMINATION; DRUG PACKAGING; ETOPOSIDE; FLUOROURACIL; FUNGI; INFUSIONS, INTRAVENOUS; PHARMACEUTICAL SOLUTIONS; STERILIZATION;

EID: 18744392011     PISSN: 10781552     EISSN: None     Source Type: Journal    
DOI: 10.1191/1078155205jp143oa     Document Type: Article

References (21)

1. Paci A, Mercier L, Bourget P. Identification and quantitation of anti-neoplastic compounds in chemotherapeutic infusion bags by use of HPTLC: application to the vinca-alkaloids. J Pharm Biomed Anal 2003; 30: 1603-10.
2. Hamilton-Miller JMT. Antimicrobial activity of 21 anti-neoplastic agents. Br J Cancer 1984; 49: 367-69.
3. Bodet CA, Jorgensen JH, Drutz DJ. Antibacterial activities of anti-neoplastic agents. Antimicrobial Agents Chemother 1985; 28: 437-39.
4. Briceland LL, Fudin J, Johnston KR. Evaluation of microbial growth in select inoculated anti-neoplastic solutions. Hosp Pharm 1990; 25: 338-40, 359.
5. Gaj E, Griffin RE. Evaluation of growth of six microorganisms in fluorouracil, bacteriostatic sodium chloride 0.9% and sodium chloride 0.9% media. Hosp Pharm 1983; 18: 348-49.
6. Gieringer JH, Wenz AF, Just HM, Daschner FD. Effect of 5-fluorouracil, mitoxantrone, methotrexate, and vincristine on the antibacterial activity of ceftriaxone, ceftazidime, cefotiam, piperacillin, and netilmicin. Chemotherapy 1986; 32: 418-24.
7. Holmes CJ, Kubey WY, Love DI. Viability of microorganisms in fluorouracil and cisplatin small-volume injections. Am J Hosp Pharm 1988; 45: 1089-91.
8. Patel K, Craig SB, McBride MG, Palepu NR. Microbial inhibitory properties and stability of topotecan hydrochloride injection. Am J Health Syst Pharm 1998; 55: 1584-87.
9. Kramer I Viability of microorganisms in novel anti-neoplastic and antiviral drug solutions. J Oncol Pharm Practice 1998; 4: 32-37.
10. Kramer I, Wenchel HM. Viability of microorganisms in anti-neoplastic drug solutions. Eur J Hosp Pharm 1991; 1: 14-19.
11. Quebbeman EJ, Hoffman NE, Ausman RK, Hamidd AA. Stability of mitomycin admixtures. Am J Hosp Pharm 1985; 42: 1750-54.
12. Li S, Wang W, Chu J, Zamansky I, Tyle P, Rowlings C. Degradation mechanism and kinetic studies of a novel anticancer agent, AG2034. Int J Pharm 1998; 167: 49-56.
13. Cazin JL, Gosselin P. Implementing a multiple-isolator unit for centralized preparation of cytotoxic drugs in a cancer center pharmacy. Pharm World Sci 1999; 21: 177-83.
14. Anonymous. Biological methods. In European pharmacopeia, 4th edition. 2002; 129: 3372-76.
15. Anonymous. Sterility tests. In The United States pharmacopeia, 22nd rev., and The national formulary, 17th edition. Rockville, MD: The United States Pharmacopeial Convention, 1989: 1483-88.
16. Schmitt E. La présentation unitaire des médicaments: point de vue d'un pharmacien hospitalier. STP Pharm Pratiques 1999; 9: 187-200.
17. Whyte W, Niven L, Bell NDS. Microbial growth in small-volume pharmaceuticals. J Parenter Sci Technol 1989; 43: 208-12.
18. Kinnunen U, Koistinen P, Syrjälä H, Koskela M. Effects of anti-neoplastic agents on the recovery of bacteria and yeasts in an automated blood culture system. Scand J Infect Dis 2000; 32: 63-67.
19. Xu Q, Trissel LA, Martinez JF. Stability of paclitaxel in 5% dextrose injection or 0.9% sodium chloride injection at 4, 22 or 32°C. Am J Hosp Pharm 1994; 51: 3058-60.
20. Akers MJ, Wright GE, Carlson KA. Sterility testing of antimicrobial-containing injectable solutions prepared in the pharmacy. Am J Hosp Pharm 1991; 48: 2414-18.
21. Buchanan EC, Scheinder PJ, Switzky H, Trissel LA. Draft guidelines on quality assurance for pharmacy-prepared sterile products. Am J Hosp Pharm 1992; 49: 407-17.