The effects of anaesthesia on cortical stimulation in rats: A functional MRI study

Australasian Physical and Engineering Sciences in Medicine

Volumn 28, Issue 1, 2005, Pages 21-25

  Dashti, M ^a,b   Geso, M ^a   Williams, J ^c  

^a RMIT UNIVERSITY   (Australia)

^b KUWAIT UNIVERSITY   (Kuwait)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Equithesin; fMRI; Isoflurane; Rat brain

Indexed keywords

BRAIN; DRUG PRODUCTS; MAGNETIC RESONANCE IMAGING; NEURAL NETWORKS; SIGNAL PROCESSING;

AIR PUFFS; ANAESTHESIA; FUNCTIONAL MODALITIES; SIGNAL RESPONSE;

BIOMEDICAL ENGINEERING;

ANESTHETIC AGENT; EQUITHESIN; ISOFLURANE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN FUNCTION; CORRELATION ANALYSIS; ELECTROENCEPHALOGRAM; FACE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; MALE; NONHUMAN; RAT; RAT STRAIN; SENSORY CORTEX; SENSORY STIMULATION; SIGNAL DETECTION;

EID: 18744391699     PISSN: 01589938     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03178860     Document Type: Article

References (16)

1. Beckmann, N., Laurent, D., Tigani, B., Panizzutti, R. and Rudin, M., Magnetic resonance imaging in drug discovery: lessons from disease areas, Drug Discov. Today, 9(1): 35-42, 2004.
2. Karlsson, J., Love, R., Clarke, D. and Brudin, P., Effects of anaesthetics and lazaroid U-83836E on survival of transplanted rat dopaminergic neurons, Brain Res., 821: 546-550, 1999.
3. Gaese, B. and Ostwald, J., Anesthesia changes frequency tuning of neurons in the rat primary auditory cortex, J. Neurophysiol., 86: 1062-1066, 2001.
4. Erulkar, S., Rose, J. and Davies, P., Single unit activity in the auditory cortex of the cat, Bull John Hopkins Hosp., 99: 55-86, 1956.
5. Love, R., Branton, R. and Clarke, D., Effects of anaesthetics on survival of rat fetal dopaminergic neurons, Brain Res. Assoc. Abstr., 14: 32, 1997.
6. Heinke, W. and Schwarzbauer, C., Subanesthetic isoflurane affects task-induced brain activation in a highly specific manner, Anesthesiology, 94: 973-81, 2001.
7. Izraeli, R., Wollberg, Z. and Dmi'el, R., Equithesin: a hibernation-inducing drug?, Comp. Biochem. Physiol. C, 103(2): 273-5, 1992.
8. Dunnett, S., Torres, E., Richards, H. and Barker, R., Effects of surgical anaesthesia on the viability of nigral grafts in the rat striatum, Cell Transpl., 7: 567-572, 1998.
9. Patel, P., Drummond, J., Cole, D. and Goskowicz, R., Isoflurane reduces ischemia-induced glutamate release in rats subjected to forebrain ischemia, Anesthesiology, 82: 996-1003, 1995.
10. Zarchin, N., Guggenheimer-Furman, E., Meilin, S., Ornstein, A. and Mayevski, A., Thiopental induced cerebral protection during ischemia in gerbils, Brain Res., 780: 230-236, 1998.
11. Paxinos, G. and Watson, C., The rat brain in stereotaxic coordinates, Academic Press, USA, 1997.
12. Deacon, R. and Rawlins, J., Equithesin without chloral hydrate as an anaesthetic for rats, Psychopharmacology, 124: 288-290, 1996.
13. Schwarting, R. and Huston, J., Short-term effects of ether, equithesin and droperidol/fentanyl on catecholamine and indolamine metabolism in the brain of the rat, Neuropharmacology, 26(5): 457-461, 1987.
14. Seiyama, A., Seki, J., Tanabe, H.C., Ooi, Y., Satomura, Y., Fujisaki, H. and Yanagida, T., Regulation of oxygen transport during brain activation: stimulus-induced hemodynamic responses in human and animal cortices, Dyn. Med., 2(1): 6, 2003.
15. Ances, B., Coupling of changes in cerebral blood flow with neural activity: what must initially dip must come back up, J. Cereb. Blood Flow Metab., 24(1): 1-6, 2004.
16. Lenz, C., Frietsch, T., Futterer, C., Rebel, A., van Ackern, K., Kuschinsky, W. and Waschke, K.F., Local coupling of cerebral blood flow to cerebral glucose metabolism during inhalational anesthesia in rats: desflurane versus isoflurane, Anesthesiology, 91(6): 1720-3, 1999.