A population approach to study the influence of nevirapine administration on lopinavir pharmacokinetics in HIV-1 infected patients

European Journal of Clinical Pharmacology

Volumn 61, Issue 2, 2005, Pages 153-156

  Dailly, Eric ^a   Reliquet, Véronique ^a   Raffi, François ^a   Jolliet, Pascale ^a  

^a HÔTEL DIEU   (France)

Author keywords

Interaction; Lopinavir; Nevirapine; Pharmacokinetics

Indexed keywords

LOPINAVIR PLUS RITONAVIR; NEVIRAPINE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ADULT; ARTICLE; DRUG BLOOD LEVEL; DRUG CLEARANCE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PRIORITY JOURNAL;

ADULT; ANTI-HIV AGENTS; BAYES THEOREM; DRUG INTERACTIONS; FEMALE; HIV INFECTIONS; HUMANS; MALE; NEVIRAPINE; PYRIMIDINONES; REVERSE TRANSCRIPTASE INHIBITORS;

EID: 18744374174     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-005-0900-2     Document Type: Article

References (8)

1. Benson CA, Deeks SG, Brun SC, Gulick RM, Eron JJ, Kessler HA et al (2002) Safety and antiviral activity at 48 weeks of lopinavir/ritonavir plus nevirapine and 2 nucleoside reverse-transcriptase inhibitors in human immunodeficiency virus type 1-infected protease inhibitor-experienced patients. J Infect Dis185:599-607
2. Solas C, Poizot-Martin I, Drogoul MP, Ravaux I, Dhiver C, Lafeuillade A et al (2004) Therapeutic drug monitoring of lopinavir/ritonavir given alone or with a non-nucleoside reverse transcriptase inhibitor. Br J Clin Pharmacol 57:436-440
3. Cvetkovic RS, Goa KL (2003) Lopinavir/ritonavir: a review of its use in the management of HIV infection. Drugs 63:769-802
4. Smith PF, DiCenzo R, Morse GD (2001) Clinical pharmacokinetics of non-nucleoside reverse transcriptase inhibitors. Clin Pharmacokinet 40:893-905
5. Dailly E, Raffi F, Jolliet P (2004) Determination of atazanavir and other antiretroviral drugs (indinavir, amprenavir, nelfinavir and its active metabolite M8, saquinavir, ritonavir, lopinavir, nevirapine and efavirenz) plasma levels by high performance liquid chromatography with UV detection. J Chromatogr B Biomed Sci Appl 813:353-358
6. Urien S (1994) Micropharm population (MP2) - an interactive and user-friendly interfaced program for population pharmacokinetics. In: Proceedings of the second meeting of the population approach group in Europe (PAGE), 13-14 June 1994, Greenford, London, UK
7. Sheiner LB, Rosenberg B, Melmon KL (1972) Modelling of individual pharmacokinetics for computer-aided drug dosage. Comput Biomed Res 5:411-459
8. Delfraissy JF (2004) In: Médecine-sciences flammarion (ed), Prise en charge des personnes infectées par le VIH. Recommandations du groupe d'experts, Paris, p. 127.