Increased activity of lysosomal enzymes in the peritoneal fluid of patients with gynecologic cancers and pelvic inflammatory disease

Journal of Cancer Research and Clinical Oncology

Volumn 131, Issue 6, 2005, Pages 371-376

  Beratis, N G ^a   Kaperonis, A ^a   Eliopoulou, M I ^a   Kourounis, G ^a   Tzingounis, V A ^a  

^a UNIVERSITY OF PATRAS   (Greece)

Author keywords

Benign ovarian cyst; Endometrial carcinoma; Lysosomal enzymes; Ovarian cancer; Pelvic inflammatory disease

Indexed keywords

ALPHA MANNOSIDASE; BETA GALACTOSIDASE; BETA GLUCURONIDASE; HYMECROMONE; LYSOSOME ENZYME;

ARTICLE; BENIGN TUMOR; CANCER CELL; CANCER STAGING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; FEMALE; GYNECOLOGIC CANCER; HUMAN; OVARY CYST; PELVIC INFLAMMATORY DISEASE; PERITONEAL FLUID; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ADENOCARCINOMA; ADENOCARCINOMA, CLEAR CELL; ADENOCARCINOMA, MUCINOUS; ALPHA-MANNOSIDASE; ASCITIC FLUID; BETA-GALACTOSIDASE; CASE-CONTROL STUDIES; CYSTADENOCARCINOMA, SEROUS; ENDOMETRIAL NEOPLASMS; FEMALE; GLUCURONIDASE; HUMANS; HYMECROMONE; LYSOSOMES; NEOPLASMS; OVARIAN CYSTS; OVARIAN NEOPLASMS; PELVIC INFLAMMATORY DISEASE;

EID: 18744369076     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-004-0649-5     Document Type: Article

References (15)

1. Beratis NG, Mavrommatis T, Hatiris I, Kavaliotis J, Tsagaropoulou-Stiga H, Syrogiannopoulos GA (1997) Increased activity of lysosomal acid hydrolases in the cell-free cerebrospinal fluid of bacterial meningitis. Pediatr Res 41:235-241
2. Beratis NG, Georgien G, Eliopoulou M (2002) Increased activity of lysosomal enzymes in the peritoneal fluid of bacterial peritonitis. Pediatrics 109:E44
3. Beratis NG, Eliopoulou MI, Syrogiannopoulos GA (2003) β-Glucuronidase in the diagnosis of bacterial meningitis and responce to treatment. Acta Paediatr 92:1272-1276
4. Berchem G, Glondu M, Gleizes M, Brouillet JP, Vignon F, Garcia M, Liaudet-Coopman E (2002) Cathepsin-D affects multiple tumor progression steps in vivo: proliferation, angiogenesis and apoptosis. Oncogene 21:5951-5955
5. Erickson AH, Blobel G (1979) Early events in the biosynthesis of the lysosomal enzyme cathepsin D. J Biol Chem 254:11771-11774
6. International Federation of Gynecology and Obstetrics (1991) Annual report on the results of treatment in gynecological cancer. Int J Gynecol Obstet: 36[Supp]:132-240
7. Kornfeld S (1986) Trafficking of lysosomal enzymes in normal and disease states. J Clin Invest 77:1-6
8. Lösch A, Schindl M, Kohlberger P, Lahodny J, Breitenecker G, Horvat R, Birner P (2004) Cathepsin D in ovarian cancer: prognostic value and correlation with p53 expression and microvessel density. Gynecol Oncol. 92:545-552.
9. Mathieu M, Rochefort H, Barenton B, Prébois C, Vignon F (1990) Interactions of cathepsin-D and insulin-like growth factor-II (IGF-II) on the IGF-II/mannose-6-phosphate receptor in human breast cancer cells and possible consequences on mitogenic activity of IGF-II. Mol Endocrinol 4:1327-1335
10. Mikkelsen T, Yan PS, Ho KL, Sameni M, Sloane BF, Rosenblum ML (1995) Immunolocalization of cathepsin B in human glioma: implications for tumor invasion and angiogenesis. J Neurosurg 83:285-290
11. Proia RL, Neufeld EF (1982) Synthesis of β-hexosaminidase in cell-free translation and in intact fibroblasts: an insoluble precursor α chain in a rare form of Tay-Sachs disease. Proc Natl Acad Sci USA 79:6360-6364
12. Rosenfeld MG, Kreibich G, Popov D, Kato K, Sabatini DD (1982) Biosynthesis of lysosomal hydrolyses: their synthesis in bound polysomes and the role of co- and post-translational processing in determining their subcellular distribution. J Cell Biol 93:135-143
13. Vetvicka V, Vetvickova J, Hilgert I, Voburka Z, Fusek M (1997) Analysis of the interaction of procathepsin D activation peptide with breast cancer cells. Int J Cancer 73:403-409
14. Vlacha V, Eliopoulou M, Haidas S, Beratis NG (2004) Correlation of cerebrospinal fluid β-glucuronidase activity with plasma methotrexate concentrations in leukemic children receiving high dose methotrexate. Pediatr Blood Cancer 42:350-356
15. Vladutiu GD, Rattazzi M (1979) Excretion-reuptake route of β-hexosaminidase in normal and I-cell disease cultured fibroblasts. J Clin Invest 63:595-601