Evidence for the involvement of spinal cord α1 adrenoceptors in nitrous oxide-induced antinociceptive effects in fischer rats

Anesthesiology

Volumn 97, Issue 6, 2002, Pages 1458-1465

  Orii, Ryo ^b   Ohashi, Yoko ^b   Guo, Tianzhi ^b   Nelson, Laura E ^b   Hashimoto, Toshikazu ^b   Maze, Mervyn ^b   Fujinaga, Masahiko ^a  

^a CHELSEA AND WESTMINSTER HOSPITAL   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; METHYSERGIDE; NALOXONE; NITROUS OXIDE; OPIATE ANTAGONIST; PRAZOSIN; PROTEIN C FOS; SEROTONIN ANTAGONIST; TROPISETRON; YOHIMBINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; GABAERGIC SYSTEM; IMMUNOHISTOCHEMISTRY; INTERNEURON; MALE; NERVE CONDUCTION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN LOCALIZATION; RAT; SPINAL CORD;

ANALGESICS, NON-NARCOTIC; ANIMALS; ATMOSPHERE EXPOSURE CHAMBERS; MALE; NITROUS OXIDE; PAIN; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, INBRED F344; RECEPTORS, ADRENERGIC, ALPHA; SPINAL CORD;

EID: 18744366042     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200212000-00018     Document Type: Article

References (37)

1. Fujinaga M, Maze M: Neurobiology of nitrous oxide induced antinociceptive effects. Mol Neurobiol 2002; 25:167-89
2. Hashimoto T, Maze M, Ohashi Y, Fujinaga M: Nitrous oxide activates GABAergic neurons in the spinal cord in Fischer rats. Anesthesiology 2001; 95:463-9
3. 2 adrenergic receptors in the rat. Anesthesiology 1996; 85:846-52
4. 2-adrenergic agonist dexmedetomidine. Anesthesiology 1998; 88:1634-42
5. Dryden S, Wang Q, Frankish HM, Pickavance L, Williams G: The serotonin (5-HT) antagonist methysergide increases neuropeptide Y (NPY) synthesis and secretion in the hypothalamus of the rat. Brain Res 1995; 699:12-8
6. Consolo S, Bertorelli R, Russi G, Zambelli M, Ladinsky H: Serotonergic facilitation of acetylcholine release in vivo from rat dorsal hippocampus via serotonin 5-HT3 receptors. J Neurochem 1994; 62:2254-61
7. Fender C, Fujinaga M, Maze M: Strain differences in the antinociceptive effect of nitrous oxide on the tail flick test in rats. Anesth Analg 2000; 90:195-9
8. Presley RW, Menétrey D, Levine JD, Basbaum AI: Systemic morphine suppresses noxious stimulus-evoked Fos protein-like immunoreactivity in the rat spinal cord. J Neurosci 1990; 10:323-35
9. 2C adrenoceptor subtypes in mice. Anesthesiology 1999; 90:470-6
10. Baba H, Goldstein PA, Okamoto M. Kohno T, Ataka T, Yoshimura M, Shimoji K: Norepinephrine facilitates inhibitory transmission in substantia gelatinosa of adult rat spinal cord: II. Effects on somatodendritic sits of GABAergic neurons. Anesthesiology 2000; 92:485-92
11. Clark FM, Proudfit HK: The projection of noradrenergic neurons in the A7 catecholamine cell group to the spinal cord in the rat demonstrated by anterograde tracing combined with immunocytochemistry. Brain Res 1991; 547:279-88
12. Sluka KA, Westlund KN: Spinal projections of the locus coeruleus and the nucleus subcoeruleus in the Harlan and the Sasco Sprague-Dawley rat. Brain Res 1992; 579:67-73
13. Clark FM, Proudfit HK: Anatomical evidence for genetic differences in the innervation of the rat spinal cord by noradrenergic locus coeruleus neurons. Brain Res 1992; 591:44-53
14. Ohara A, Zhang P, Inagaki Y, Mashimo T, Yoshiya I: Nitrous oxide analgesia: Existence of acute tolerance and complete antagonism by yohimbine. Anesth Rcsusci 1995; 31:37-9
15. Berkowitz BA, Ngai SH, Finck AD: Nitrous oxide analgesia: Resemblance to opiate action. Science 1976; 194:967-8
16. Berkowitz BA, Finck AD, Ngai SH: Nitrous oxide analgesia: Reversal by naloxone and development of tolerance. JPET 1977; 203:539-47
17. Lawrence D, Livingston A: Opiate-like analgesic activity in general anaesthetics. Br J Pharm 1981; 73:435-42
18. Zuniga J, Joseph S, Knigge K: Nitrous oxide analgesia: Partial antagonism by naloxone and total reversal after periaqueductal gray lesions in the rat. Eur J Pharm 1987; 142:51-60
19. Quock RM, Walczak CK, Henry RJ, Chen DC: Effect of subtype-selective opioid receptor blockers on nitrous oxide antinociception in rats. Pharmacol Res 1990; 22:351-7
20. Hodges BL, Gagnon MJ, Gillespie TR, Breneisen JR, O'Leary DF, Hara S, Quock RM: Antagonism of nitrous oxide antinociception in the rat hot plate test by site-specific mu and epsilon opioid receptor blockage. JPET 1994; 269:596-600
21. Goto T, Marota JJA, Crosby G: Nitrous oxide induces preemptive analgesia in the rat that is antagonized by halothane. Anesthesiology 1994; 80:409-16
22. Levine JD, Gordon NC, Fields HL: Naloxone fails to antagonize nitrous oxide analgesia for clinical pain. Pain 1982; 13:165-9
23. Yagi M, Mashimo T, Kawaguchi T, Yoshiya I: Analgesic and hypnotic effects of subanaesthetic concentrations of xenon in human volunteers: Comparison with nitrous oxide. Br J Anaesth 1995; 74:670-3
24. Zacny JP, Conran A, Pardo H, Coalson DW, Black M, Klock PA, Klaft JM: Effects of naloxone on nitrous oxide actions in healthy volunteers. Pain 1999; 83:411-8
25. Ohara A, Mashimo T, Zhang P, Inagaki Y, Shibuta S, Yoshiya I: A comparative study of the antinociceptive action of xenon and nitrous oxide in rats. Anesth Analg 1997; 85:931-6
26. Fukuhara N, Ishikawa T, Kinoshita H, Xiong L, Nakanishi O: Central noradrenergic mediation of nitrous oxide-induced analgesia in rats. Can J Anaesth 1998; 45:1123-9
27. Gillman MA: Pharmacokinetic differences could explain the lack of reversal of nitrous oxide analgesia by low-dose naloxone. Anesthesiology 1986; 65:449-50
28. Basbaum AL, Fields HL: Endogenous pain control systems: Brainstem spinal pathways and endorphin circuitry. Annu Rev Neurosci 1984; 7:309-38
29. Ohashi Y, Stowell JM, Orii R, Maze M, Fujinaga M: Neural nuclei activated by nitrous oxide in Fischer rats (abstract). Anesthesiology 2001; 95:A-721
30. Mueller JL, Quock RM: Contrasting influences of 5-hydroxytryptamine receptors in nitrous oxide antinociception in mice. Pharmacol Biochem Behav 1992; 41:429-32
31. Lin JS, Sakai K, Jouvet M: Evidence for histaminergic arousal mechanisms in the hypothalamus of cat. Neuropharmacol 1988; 27:111-22
32. Lin JS, Hou Y, Sakai K, Jouvet M: Histaminergic descending inputs to the mesopontine tegmentum and their role in the control of cortical activation and wakefulness in the cat. J Neurosci 1996; 16:1523-37
33. Gallopin T, Fort P, Eggermann E, Cauli B, Luppi PH, Rossier J, Audinat E, Muhlethaler M, Serafin M: Identification of sleep-promoting neurons in vitro. Nature 2000; 404:992-5
34. 2 agonist, is mediated in the locus ceruleus in rats. Anesthesiology 1992; 76:948-52
35. Correa-Sales C, Nacif-Coelho C, Reid K, Maze M: Inhibition of adenylate cyclase in the locus coeruleus mediates the hypnotic response to an alpha 2 agonist in the rat. JPET 1992; 263:1046-9
36. Osborne PB, Vidovic M, Chieng B, Hill CE, Christie MJ: Expression of mRNA and functional alpha(1)-adrenoceptors that suppress the GIRK conductance in adult rat locus coeruleus neurons. Br J Pharm 2002; 135:226-32
37. Sawamura S, Kingery WS, Davies MF, Agashe GS, Clark JD, Kobilka BK, Hashimoto T, Maze M: Antinociceptive action of nitrous oxide is mediated by stimulation of noradrenergic neurons in the brainstem and activation of α2B adrenoceptors. J Neurosci 2000; 20:9242-51